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Medicine for treating gingivitis caused by kidney yin deficiency and preparation method of medicine

A technology for gingivitis and medicine, which is applied in the field of pharmaceutical preparations, can solve the problems of gingivitis with many side effects, unsatisfactory clinical curative effect, inconvenient route of administration, etc., and achieve the goal of no side effects, short treatment period and quick onset of action Effect

Inactive Publication Date: 2015-06-17
山东三生新材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, Western medicine treatment of gingivitis has more toxic and side effects, longer course of treatment, inconvenient route of administration, and unsatisfactory clinical curative effect, which causes inconvenience to the lives of patients.

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0072] Wherein, when the dosage form of described medicine is mouthwash, its preparation method comprises the following steps:

[0073] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixture composed of micron-sized particles with a volume average particle size of 0.1-10 μm and nano-sized particles with a volume-average particle size of less than 0.1 μm Powder, the powder yield of the mixed powder is at least 95%;

[0074] In the second step, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixed powder that is 3 to 5 times the mass of the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and put the ethanol solution in Stand still for 24-36 hours under the condition of 5°C-10°C, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, concentrate and dry, and put it into ...

Embodiment 1

[0086] Example 1 Mouthwash

[0087] The preparation process of mouthwash of the present invention is: get Rehmannia glutinosa 120g, Chickweed 230g, Polygonum multiflorum 300g, Scutellaria vine 280g, Mushizi 220g, Aster single head 300g, Dendrobium 250g, Polygonum polycysticum 300g, Polygonatum 260g, Field snail 200g, Lycium barbarum 190g, Eclipta 220g, Ligustrum lucidum 250g, Ligustrum lucidum 180g, Agarwood 200g, Mulberry 260g, Ophiopogon japonicus 300g, Angelica 170g, Buckwheat straw 310g, Codonopsis 300g, Jasmine grass 340g, Ziheche 230g, Cuscuta 300g, 340g of bitter gourd, 230g of Eucommia ulmoides, 150g of pandanus, 240g of cypress kernels, 270g of radish, 320g of ganoderma, 30g of sage, 330g of calamus, 250g of sage, 350g of eleuthero and 200g of chrysanthemum;

[0088] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixed powder composed of micron-sized particles with a volume average particl...

Embodiment 2

[0091] Example 2 Spray

[0092] The production process of the spray of the present invention is as follows: take rehmannia glutinosa 300g, chickweed 200g, Polygonum multiflorum 150g, rice field eel vine 240g, mulberry seed 150g, single-headed aster 280g, dendrobium 220g, Polygonum polycysticum 180g, sealwort 320g, snail 200g , Lycium barbarum 170g, Eclipta 220g, Loropetalum 250g, Ligustrum lucidum 300g, Agarwood 220g, Mulberry 250g, Ophiopogon japonicus 280g, Angelica 240g, Buckwheat straw 310g, Codonopsis 260g, Jasmine 330g, Ziheche 230g, Cuscuta 300g , bitter 310g, eucommia 270g, pandanus 200g, cypress kernel 230g, radish 300g, ganoderma lucidum 340g, capsule 40g, calamus 330g, radix 250g, thorns 340g and velvet 150g;

[0093] The first step is to mix Capsicum officinalis, Acorus calamus, Glycyrrhiza officinalis, Acanthopanax sativa and Deer's dimple, add ethanol with an alcohol concentration of 65% to 5 times the amount of the mixture, and reflux extraction for 3 times, eac...

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Abstract

The invention discloses a medicine for treating gingivitis caused by kidney yin deficiency and a preparation method of the medicine. The medicine is prepared from the following medicinal materials: radix rehmanniae praeparata, stellaria neglecta weihe, polygonum multiflorum, manyflower supplejack stem and leaf, fructus broussonetiae, turbinate aster, dendrobe, polygonum polystachyum, polygonatum kingianum, freshwater snail's operculum, wolfberry fruit, eclipta, loropetalum chinense, glossy privet fruit, agilawood, mulberry, radix ophiopogonis, angelica sinensis, buckwheat straw, codonopsis pilosula, dwarf lilyturf, human placenta, semen cuscutae, physalis angulata, eucommia ulmoides, pandanus tectorius soland, platycladi seed, metaplexis fruit, ganoderma lucidum, chinese elder, acorus tatarinowii, pennycress seed, manyprickle acanthopanax root and deer's thyroid gland. The medicine has the beneficial effects that the medicine has the effect of nourishing kidney yin and is mainly used for treating gingivitis caused by kidney yin deficiency; by virtue of the theory of the traditional Chinese medicine, on the basis of the integer concept, treatment based on syndrome differentiation is carried out by regulating dynamic balance of qi and blood, yin and yang and integral organs of the organism and internal environments of the integral organs; multi-target specific treatment is carried out; and the medicine has the advantages of being fast in acting, high in effective rate, accurate in curative effect, short in treatment course, free of a toxic or side effect and low in proce.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating kidney yin deficiency type gingivitis and a preparation method thereof. Background technique [0002] Gingivitis refers to acute and chronic inflammation that occurs in the gum tissue. Gingiva refers to the oral mucosal epithelium and the underlying connective tissue covering the surface of the alveolar process and the neck of the tooth. Dental plaque is the initiating factor of gingivitis. Gingivitis is commonly manifested as bleeding, redness, swelling, and pain of the gums, which may develop to deep layers and lead to periodontitis. Gingivitis can be caused by bacterial infection, foreign object stimulation and food impaction, etc. Generally, bacterial infection is the most common. [0003] The cause of gingivitis: The main cause of gingivitis is poor oral hygiene, which leads to the deposition of plaque, calculus and soft dirt o...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P1/02A61K35/55A61K35/50
Inventor 陈安威刘少华万凤丽王桦郭延举
Owner 山东三生新材料科技有限公司
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