Externally-used medicine composition for treating chloasma

Abstract

The invention discloses externally-used medicine composition for treating chloasma. The composition is prepared from traditional Chinese medicines in parts by weight with a water extraction method as follows: 30-42 parts of salvia chinensis benth, 11-20 parts of calyx seu fructus physalis, 30-42 parts of herba hyperici japonica, 30-42 parts of cissus hexangularis, 11-20 parts of tribulus terrestris, 11-20 parts of mulberry leaves, 6-12 parts of herba artemisiae anomalae, 11-20 parts of silene adenantha, 11-20 parts of eriobotrya japonica thumb and 9-15 parts of dandelion. The externally-used medicine composition has the effects of blood vessel warming and clearing, skin activation, stasis elimination, blood nourishment, freckle removal and skin moisturizing, can effectively expand peripheral vessels, improve microcirculation of the face and soften cutin and has a certain inhibition function on hyperpigmentation.

Description

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an external pharmaceutical composition for treating chloasma. Background technique

[0002] Melasma, commonly known as liver spots and butterfly spots, is a common facial pigmentation disease. It is a kind of yellowish brown or coffee stains of different sizes that occur around the cheeks, forehead, nose and lips. Its incidence is increasing year by year, mostly in young women, seriously affecting their life and work.

[0003] Chloasma belongs to the category of "dark spots" and "face dust" in traditional Chinese medicine. Traditional Chinese medicine believes that its etiology and pathogenesis are related to wind evil, phlegm retention, and disharmony between qi and blood. Qi stagnation due to liver depression, stagnation of Qi and blood, and stagnation of phlegm and dampness will lead to poor circulation of Qi and blood, unable to nourish the ...

Examples

Embodiment 1

[0015] The preparation of embodiment 1 Chinese medicine extract powder

[0016] Weigh Shijianchuan 0.35kg, brocade lantern 0.15kg, Tianjihuang 0.35kg, hexagonal rattan 0.35kg, Tribulus terrestris 0.15kg, mulberry leaf 0.15kg, Liu Jinu 0.09kg, black petunia 0.15kg, loquat leaf 0.15kg and Dandelion 0.12kg, then add purified water with 12 times the total weight of medicinal materials, heat and decoct for 2 hours, filter, and collect the filtrate; add purified water with 10 times the weight of medicinal materials to the medicinal residues and decoct for 1.5 hours, filter, collect the filtrate, and The two filtrates are combined, concentrated to a semi-solid extract, freeze-dried, crushed and passed through a 120-mesh sieve to obtain a medicinal powder.

Embodiment 2

[0017] Example 2 Study on the curative effect of Chinese medicine facial mask on patients with chloasma

[0018] Fifty-two patients diagnosed with female chloasma were randomly divided into 26 cases in the treatment group, including 29 to 52 years old, with an average age of (47.9±6.2) years and an average disease duration of (6.4±3.7) years; 26 cases in the control group, of which Aged 30 to 52 years old, mean (48.2±5.8) years old, mean disease duration (7.1±3.5) years. According to the statistics, there was no statistically significant difference between the two groups in terms of age, course of disease, and severity scores, and they were comparable.

[0019] Treatment group: Take 3g of medicinal powder (prepared according to the prescription process of Example 1) in a container, add a small amount of pure water to make a thick paste, add a little honey, mix well, apply a mask, apply for 30 minutes, wash off, once every other day. Control group: use 2% hydroquinone cream (t...

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to an external pharmaceutical composition for treating chloasma. Background technique

[0002] Melasma, commonly known as liver spots and butterfly spots, is a common facial pigmentation disease. It is a kind of yellowish brown or coffee stains of different sizes that occur around the cheeks, forehead, nose and lips. Its incidence is increasing year by year, mostly in young women, seriously affecting their life and work.

[0003] Chloasma belongs to the category of "dark spots" and "face dust" in traditional Chinese medicine. Traditional Chinese medicine believes that its etiology and pathogenesis are related to wind evil, phlegm retention, and disharmony between qi and blood. Qi stagnation due to liver depression, stagnation of Qi and blood, and stagnation of phlegm and dampness will lead to poor circulation of Qi and blood, unable to nourish the ...

Examples

Embodiment 1

[0015] The preparation of embodiment 1 Chinese medicine extract powder

[0016] Weigh Shijianchuan 0.35kg, brocade lantern 0.15kg, Tianjihuang 0.35kg, hexagonal rattan 0.35kg, Tribulus terrestris 0.15kg, mulberry leaf 0.15kg, Liu Jinu 0.09kg, black petunia 0.15kg, loquat leaf 0.15kg and Dandelion 0.12kg, then add purified water with 12 times the total weight of medicinal materials, heat and decoct for 2 hours, filter, and collect the filtrate; add purified water with 10 times the weight of medicinal materials to the medicinal residues and decoct for 1.5 hours, filter, collect the filtrate, and The two filtrates are combined, concentrated to a semi-solid extract, freeze-dried, crushed and passed through a 120-mesh sieve to obtain a medicinal powder.

Embodiment 2

[0017] Example 2 Study on the curative effect of Chinese medicine facial mask on patients with chloasma

[0018] Fifty-two patients diagnosed with female chloasma were randomly divided into 26 cases in the treatment group, including 29 to 52 years old, with an average age of (47.9±6.2) years and an average disease duration of (6.4±3.7) years; 26 cases in the control group, of which Aged 30 to 52 years old, mean (48.2±5.8) years old, mean disease duration (7.1±3.5) years. According to the statistics, there was no statistically significant difference between the two groups in terms of age, course of disease, and severity scores, and they were comparable.

[0019] Treatment group: Take 3g of medicinal powder (prepared according to the prescription process of Example 1) in a container, add a small amount of pure water to make a thick paste, add a little honey, mix well, apply a mask, apply for 30 minutes, wash off, once every other day. Control group: use 2% hydroquinone cream (t...