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Spray for treating or preventing beriberi and preparation method thereof

A technology for sprays and beriberi, applied in the direction of aerosol delivery, medical preparations containing active ingredients, antifungal agents, etc., can solve problems such as difficult to eradicate, recurrent attacks, easy to cause beriberi, etc., achieve preparation and use methods Simple and effective

Active Publication Date: 2015-08-05
张洪坤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Among them, the most common types of athlete’s foot are blister type, blister infection type, and wet fungus type. These types of athlete’s foot are caused by wearing inappropriate shoes; The characteristics of onset and difficult eradication bring great pain and psychological pressure to patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Example 1 : Take 1-2 parts of Chinese herbal medicine Asarum, 3-4 parts of Vitex bark, 1-2 parts of Sophora flavescens, 1-2 parts of Shegan, 3-4 parts of Cortex Phellodendri, 1-3 parts of Forsythia, 5-6 parts of Gallnut , 3-4 parts of Cangzhu, 1-2 parts of Baixianpi, 3-4 parts of Baibu, 1-2 parts of Cnidium, 3-4 parts of Kochia, 1-2 parts of Purslane, 1-2 parts of Xanthium 2 parts, 1-2 parts of Artemisia argyi, 2-3 parts of Angelica dahurica, 3-4 parts of Scutellaria baicalensis, crushed into particles below 350 μm, soaked in an ethanol solution with a concentration 65-85% 5 times the total weight of Chinese medicinal materials and refluxed Extract for 3 days, use a ≤150μm filter to filter the permeate to obtain the filtrate, add the filter residue to an ethanol solution with a concentration of 65-85% that is 3 times the total weight of the Chinese herbal medicine, and repeat the reflux extraction twice and use ≤150μm The permeate is obtained by filter press filtration...

Embodiment 2

[0013] Example 2 : Take 1-2 parts of Chinese herbal medicine Asarum, 3-4 parts of Vitex bark, 1-2 parts of Sophora flavescens, 1-2 parts of Shegan, 3-4 parts of Cortex Phellodendri, 1-3 parts of Forsythia, 5-6 parts of Gallnut , 3-4 parts of Cangzhu, 1-2 parts of Baixianpi, 3-4 parts of Baibu, 1-2 parts of Cnidium, 3-4 parts of Kochia, 1-2 parts of Purslane, 1-2 parts of Xanthium 2 parts, 1-2 parts of Artemisia argyi, 2-3 parts of Angelica dahurica, 3-4 parts of Scutellaria baicalensis, crushed into particles below 350 μm, soaked in an ethanol solution with a concentration of 65-85% 10 times the total weight of Chinese medicinal materials, and refluxed for extraction Take it for 5 days, filter the permeate with a ≤150 μm filter screen to obtain the filtrate, concentrate the filtrate to or prepare a dry matter content of 8%, add 5-7 parts of atropine, 1-3 parts of camphor, and 100 parts by weight of the filtrate. 3-5 parts of borneol and subpackage after fully dissolving.

Embodiment 3

[0014] Example 3 : Take 1-2 parts of Chinese herbal medicine Asarum, 3-4 parts of Vitex bark, 1-2 parts of Sophora flavescens, 1-2 parts of Shegan, 3-4 parts of Cortex Phellodendri, 1-3 parts of Forsythia, 5-6 parts of Gallnut , 3-4 parts of Cangzhu, 1-2 parts of Baixianpi, 3-4 parts of Baibu, 1-2 parts of Cnidium, 3-4 parts of Kochia, 1-2 parts of Purslane, 1-2 parts of Xanthium 2 parts, 1-2 parts of Artemisia argyi, 2-3 parts of Angelica dahurica, 3-4 parts of Scutellaria baicalensis, crushed into 250 μm particles, soaked in 70% ethanol solution of 3 times the total weight of Chinese medicinal materials, refluxed and extracted for 2 days , use a 150μm filter to filter the permeate to obtain the filtrate, add the filter residue to an ethanol solution with a concentration of 65-85% twice the total weight of the Chinese herbal medicine, and then repeat the reflux extraction for 3 times, each time for 1 day, all with 150μm Filter through a filter to get the permeate to obtain ...

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PUM

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Abstract

The invention discloses a spray for treating or preventing beriberi and a preparation method thereof. A medicament is mainly prepared from the following raw materials in parts by weight: 1-2 parts of manchurian wildginger, 3-4 parts of golden larch bark, 1-2 parts of light yellow sophora root, 1-2 parts of blackberrylily rhizome, 3-4 parts of bark of Chinese corktree, 1-3 parts of weeping forsythia capsule, 5-6 parts of Chinese gall, 3-4 parts of rhizome of swordlike atractylodes, 1-2 parts of densefruit pittany root-bark, 3-4 parts of sessile stemona root, 1-2 parts of common cnidium fruit, 3-4 parts of belvedere fruit, 1-2 parts of parslane herb, 1-2 parts of siberian cocklour fruit, 1-2 parts of argy wormwood leaf, 2-3 parts of dahurian angelica root and 3-4 parts of baikal skullcap root. The preparation method of the spray comprises the following steps: taking traditional Chinese medicinal materials, completely soaking into a 65-85% ethanol solution, performing reflux extraction to obtain a filtrate, then adding 5-7 parts of atropine, 1-3 parts of camphor and 3-5 parts of borneol into the filtrate, and fully dissolving. Compared with existing similar medicines, the medicine formula, the preparation method and the application method disclosed by the invention are very simple; and the spray can be sprayed or coated outside an affected part, or can also be sprayed on shoes and socks, is good in use effect, and is particularly suitable for diseases such as foot odor, foot itching, foot blistering and body odor caused by fungi.

Description

technical field [0001] The invention relates to a spray for treating or preventing beriberi and a preparation method thereof. Background technique [0002] Tinea manus, pedis and pruritus are common difficult diseases, especially beriberi, which is a kind of intractable skin disease, divided into blister type, blister infection type, scale type, keratosis type, keratosis thickening type, Rotten type, wet fungus type, sweaty fungus compound beriberi, etc. [0003] Among them, the most common types of athlete’s foot are blister type, blister infection type, and wet fungus type. These types of athlete’s foot are caused by wearing inappropriate shoes; The characteristics of onset and difficult eradication bring great pain and psychological pressure to patients. Contents of the invention [0004] The purpose of the present invention is to provide a spray for treating or preventing athlete's foot and a preparation method thereof. [0005] The medicament of the present inventi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/12A61P17/00A61P31/10A61K35/64A61K31/46
Inventor 张洪坤
Owner 张洪坤
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