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Medicine composition for treating coronary heart disease and preparation method thereof

A composition and technology for coronary heart disease, applied in drug combinations, pharmaceutical formulas, cardiovascular system diseases, etc., can solve the problems of complex chemical components, weak mechanism research, and single effect of traditional Chinese medicine

Inactive Publication Date: 2015-12-23
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine has a clear mechanism of action in the treatment of coronary heart disease, and the effect is rapid, but the effect is single, and each drug has only one effect or acts on one link
The chemical composition of traditional Chinese medicine is complex, and the mechanism research is still weak

Method used

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  • Medicine composition for treating coronary heart disease and preparation method thereof
  • Medicine composition for treating coronary heart disease and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition for the treatment of coronary heart disease and preparation method thereof

[0039] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of coronary heart disease are:

[0040] 75 parts by weight of snails, 70 parts by weight of snails, 50 parts by weight of delphinium cucurbitacin E, 5.5 parts by weight of cucurbitacin E, 3.5 parts by weight of alistinol B, 2.5 parts by weight of alisatidinol A;

[0041] Preparation:

[0042] (1) According to the ratio of raw materials, take the meshed Vavet and snail powder, mix them evenly, crush them through a 40-mesh sieve, use ethanol with a concentration of 70% by weight as a solvent, and extract by percolation at 35°C. The number of extractions is 3 times, and each extraction is The time is 1.5 hours, and the amount of solvent used each time is 22 times of the total weight of the meshed vavet and snail medicinal materials to obtain...

Embodiment 2

[0045] Embodiment 2: the pharmaceutical composition for the treatment of coronary heart disease and its preparation method

[0046] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of coronary heart disease are:

[0047] 70 parts by weight of snails, 75 parts by weight of snails, 45 parts by weight of delphinium cucurbitacin E, 6 parts by weight of alisatiol B3 parts by weight, and 3 parts by weight of alisatiol A3;

[0048] Preparation:

[0049] (1) According to the ratio of raw materials, take the meshed Vavet and snail powder, mix them evenly, crush them through a 40-mesh sieve, use ethanol with a concentration of 70% by weight as a solvent, and extract by percolation at 35°C. The number of extractions is 3 times, and each extraction is The time is 1.5 hours, and the amount of solvent used each time is 22 times of the total weight of the meshed vavet and snail medicinal materials to obtain the medicinal residue A and...

Embodiment 3

[0052] Embodiment 3: the pharmaceutical composition for the treatment of coronary heart disease and its preparation method

[0053] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of coronary heart disease are:

[0054] 80 parts by weight of Mesh Vave, 65 parts by weight of snails, 55 parts by weight of delphinium, 55 parts by weight of cucurbitacin E5 parts by weight, alisol B4, and 2 parts by weight;

[0055] Preparation:

[0056] (1) According to the ratio of raw materials, take the meshed Vavet and snail powder, mix them evenly, crush them through a 40-mesh sieve, use ethanol with a concentration of 70% by weight as a solvent, and extract by percolation at 35°C. The number of extractions is 3 times, and each extraction is The time is 1.5 hours, and the amount of solvent used each time is 22 times of the total weight of the meshed vavet and snail medicinal materials to obtain the medicinal residue A and the extract,...

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Abstract

The invention discloses a medicine composition for treating coronary heart disease and a preparation method thereof. The medicine composition is prepared by taking lepisorus clathratus, littleleaf lemmaphyllum, herba delphinii, cucurbitacine E, rhizoma alismatis terpene alcohol B and rhizoma alismatis terpene alcohol A as crude drugs and proportioning. The medicine composition can be prepared into various preparations according to a conventional preparation process and has a remarkable curative effect on treating coronary heart disease.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating coronary heart disease and a preparation method thereof. Background technique [0002] Coronary heart disease (Coronary Heart Disease), also known as ischemic heart disease (Ischemic Heart Disease) or coronary heart disease (Coronary Cardiopathy), includes coronary atherosclerosis that narrows and blocks blood vessels and coronary artery spasm, leading to heart disease caused by myocardial ischemia and hypoxia. sick. Angina pectoris (Angina Pectoris) is the most common type of coronary heart disease, which is a clinical syndrome caused by coronary insufficiency, myocardial acute and temporary ischemia and hypoxia. There is no disease name for coronary heart disease in ancient Chinese literature, but similar symptoms have been recorded for a long time. This disease belongs to the categories of "chest pain...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P9/10
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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