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Package of sodium bicarbonate injection

A technology of sodium bicarbonate and injection, which is applied in the field of pharmaceutical packaging, can solve the problems of sodium bicarbonate injection pH value exceeding the limit and short storage period, and achieve the effects of improving long-term storage stability, preventing loss, and overcoming decomposition problems

Active Publication Date: 2016-01-27
SICHUAN KELUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For above problem, the purpose of this invention is to provide a kind of packaging of sodium bicarbonate injection, to solve sodium bicarbonate injection along with the prolongation of time, the pH value of sodium bicarbonate injection exceeds the limit, storage period is short, adds stable safety issues posed by agents

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032]A kind of packing of sodium bicarbonate injection, comprises the polypropylene infusion bottle or upright type polypropylene infusion bag for containing sodium bicarbonate injection, the first barrier outer bag, and the second barrier outer bag, polypropylene infusion bottle or The upright polypropylene infusion bag is set in the second barrier outer bag, the second barrier outer bag is set in the first barrier outer bag, the polypropylene infusion bottle or the upright polypropylene infusion bag is filled with carbon dioxide gas and nitrogen Mixed gas, the volume ratio of carbon dioxide gas and nitrogen in the mixed gas is 1:1, the volume percentage of the mixed gas is 70%, between the polypropylene infusion bottle and the second barrier outer bag or the upright polypropylene infusion bag and the second barrier A mixed gas composed of carbon dioxide and nitrogen is filled between the outer bags. The volume ratio of carbon dioxide gas and nitrogen in the mixed gas is 1:1,...

Embodiment 2

[0039] A kind of packing of sodium bicarbonate injection, comprises the polypropylene infusion bottle or upright polypropylene infusion bag that is used to contain sodium bicarbonate injection first barrier outer bag, and the second barrier outer bag, polypropylene infusion bottle or upright The polypropylene infusion bag is set in the second barrier outer bag, the second barrier outer bag is set in the first barrier outer bag, and the polypropylene infusion bottle or the upright polypropylene infusion bag is filled with a mixture of carbon dioxide and nitrogen. Gas, the volume ratio of carbon dioxide gas and nitrogen in the mixed gas is 3:1, the volume percentage of the mixed gas is 80%, between the polypropylene infusion bottle and the second barrier outer bag or the upright polypropylene infusion bag and the second barrier outer bag The bags are filled with a mixed gas composed of carbon dioxide and nitrogen, the volume ratio of carbon dioxide gas and nitrogen in the mixed g...

Embodiment 3

[0046] A kind of packing of sodium bicarbonate injection, comprises the polypropylene infusion bottle or upright type polypropylene infusion bag for containing sodium bicarbonate injection, the first barrier outer bag, and the second barrier outer bag, polypropylene infusion bottle or The upright polypropylene infusion bag is set in the second barrier outer bag, the second barrier outer bag is set in the first barrier outer bag, the polypropylene infusion bottle or the upright polypropylene infusion bag is filled with carbon dioxide gas and nitrogen Mixed gas, the volume ratio of carbon dioxide gas and nitrogen in the mixed gas is 2:1, the volume percentage of the mixed gas is 90%, between the polypropylene infusion bottle and the second barrier outer bag or the upright polypropylene infusion bag and the second barrier A mixed gas composed of carbon dioxide and nitrogen is filled between the outer bags. The volume ratio of carbon dioxide gas and nitrogen in the mixed gas is 2:1...

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Abstract

The invention discloses a package of a sodium bicarbonate injection. The package comprises a polypropylene infusion bottle or a vertical polypropylene infusion bottle bag used for containing the sodium bicarbonate injection, wherein the polypropylene infusion bottle or the vertical polypropylene infusion bottle bag is arranged in a second blocking outer bag; the second blocking outer bag is arranged in a first blocking outer bag; the polypropylene infusion bottle or the vertical polypropylene infusion bottle bag is filled with mixed gas; a position between the polypropylene infusion bottle or the vertical polypropylene infusion bottle bag and the second blocking outer bag is filled with mixed gas; and a position between the second blocking outer bag and the first blocking outer bag is filled with nitrogen gas. The polypropylene infusion bottle or the vertical polypropylene infusion bottle bag is filled with the mixed gas of carbon dioxide and the nitrogen gas; the mixed gas can completely replace the effect of stabilizing agents in the injection; the side effects due to stabilizing agent addition are avoided; the problem of decomposition of the sodium bicarbonate injection can be effectively solved by the package structure; the greenhouse effect is avoided; and the long-time storage stability of the injection and the medication safety of a patient are improved.

Description

technical field [0001] The invention relates to medicine packaging, in particular to a new packaging structure for sodium bicarbonate injection. Background technique [0002] As a clinical emergency drug, sodium bicarbonate injection is mainly used in the following clinical applications: (1) Treatment of metabolic acidosis: for mild to moderate metabolic acidosis, oral administration is appropriate. Severe metabolic acidosis should be administered intravenously, such as severe kidney disease, circulatory failure, cardiopulmonary resuscitation, extracorporeal circulation, severe primary lactic acidosis, diabetic ketoacidosis, etc. (2) Alkalinizing urine: It is used to prevent uric acid kidney stones, reduce the nephrotoxicity of sulfonamide and other drugs, and prevent hemoglobin from depositing in renal tubules during acute hemolysis. (3) As an antacid, treat symptoms caused by hyperacidity. (4) Intravenous infusion has a non-specific therapeutic effect on certain drug poi...

Claims

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Application Information

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IPC IPC(8): A61J1/10
Inventor 朱麟谭鸿波刘文军雷祥杰罗帅邓茂林吴小愚何颖
Owner SICHUAN KELUN PHARMA CO LTD
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