Capillary bundle flow measurement device and measurement method for nanoemulsion

Abstract

The invention discloses a capillary bundle flow measurement device for nanoemulsion, which includes a sample preparation system, a sample introduction system and a measurement system; the sample preparation system includes a first sample feed pump, a first water storage device, a second sample feed pump, a Two water reservoirs, the first intermediate container, the second intermediate container, the first mixing chamber, the second mixing chamber, the third sampling pump, the fourth sampling pump, the fourth water storage, the fourth intermediate container, mechanical mixer , electromagnetic heating stirrer and magnet; the sampling system includes the sixth sampling pump, the sixth water storage, the sixth intermediate container, the seventh intermediate container, valve one, valve two, fifth sampling pump and multi-way valve 1. The measurement system includes a capillary bundle, a multi-way valve 2, a multi-way valve 3, a pressure sensor 1, a pressure sensor 2, a data acquisition system, a data processing system and a metering container. The invention also provides a method for measuring the capillary bundle flow of the nanoemulsion by using the device, which improves the reproducibility, accuracy and usability of the flow experiment data.

Description

Technical field [0001] The invention relates to the technical field of testing fluid flow in a capillary bundle, in particular to a capillary bundle flow measuring device and a measuring method for nanoemulsion. Background technique [0002] Nanoemulsion refers to a colloidal dispersion system formed by two immiscible liquids, and the droplet size range is generally between 50 and 500 nm. The nanoemulsion has small droplet size and uniform particle size, and the amount of emulsifier is greatly reduced compared with microemulsions. Compared with ordinary emulsions, nanoemulsions have the advantages of uniform dispersion and good stability. Nanoemulsions can be used in many fields such as medicine, catalysis, food, petroleum and cosmetics, and have very good application prospects. [0003] At present, the research on the fluidity of emulsions mainly focuses on the micron-sized emulsion system, and it is the flow in porous media. Ordinary emulsions are prone to stratification, coale...

AI Technical Summary

Problems solved by technology

However, at present, due to the thermodynamic instability of the nanoemulsion particle size, the measurement of the flow law of the nanoemulsion is difficult to repeat and reproduce, which greatly limits the application of the nanoemulsion.

The patent CN201310130666 has produced a polymer-stabilized nanoemulsion through the inverse emulsification method. The method provided is to add the emulsifier and the water phase drop by drop. It takes a long time to prepare the nanoemulsion in this way, and the prolongation of the preparation time is also can lead to changes in the particle size and distribution of nanoparticles

In addition, the transfer between containers during the measurement process of the prepared nanoemulsion will have a shearing effect on the nanoemulsion particles, and the external shear stress also has a great influence on the particle size and other properties of the nanoemulsion, which leads to The inaccuracy and non-reproducibility of the measurement results, which in turn affects the evaluation of the application effect

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