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Application of oxymatrine injection in antianginal drugs

A technology of oxymatrine and injection, which is applied in the direction of drug combination, drug delivery, subcutaneous injection equipment, etc., can solve the problems of dilating blood vessels, reducing the incidence of myocardial infarction and mortality, and achieve good curative effect

Inactive Publication Date: 2016-02-17
BEIHUA UNIV
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Problems solved by technology

However, its clinical pharmacological effects of anti-angina pectoris, dilating blood vessels, and reducing the incidence of myocardial infarction and mortality have not been reported yet.

Method used

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  • Application of oxymatrine injection in antianginal drugs
  • Application of oxymatrine injection in antianginal drugs
  • Application of oxymatrine injection in antianginal drugs

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Embodiment Construction

[0010] An application of oxymatrine injection anti-angina drugs, characterized in that: oxymatrine injection is an intravenous injection prepared by diluting 2mg / ml oxymatrine with 100ml of 5% glucose; medication.

[0011] An application of oxymatrine injection anti-angina pectoris drug, characterized in that: the sitting position administration means that the height of the seat is adjusted up and down through the lifting mechanism, so that the upper limb forearm of the patient receiving the injection is on the same plane as the heart superior.

[0012] In the clinical trial of the present invention, from June 2010 to June 2014, 120 patients with angina pectoris were selected in the Affiliated Hospital of Jilin Workers Medical University, of which 64 were male and 56 were female, with an average age of 42-70 years. Patients were randomly divided into 12 groups according to their condition, sex and age. 60 cases had a course of 3 days, 46 cases had a course of 5 days, and 14 ...

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Abstract

Application of oxymatrine injection in antianginal drugs is characterized in that the oxymatrine injection is intravenous fluid prepared by diluting oxymatrine 2 mg / ml with 100 ml of 5% glucose; sitting administration is adopted that is referred to: seat height is adjusted through a lifting mechanism such that the forearm of one upper arm of a patient to take injection is on the same plane with the heart. The oxymatrine injection is the intravenous fluid prepared by diluting oxymatrine 2 mg / ml with 100 ml of 5% glucose; the sitting administration is adopted. The curative effect is 10% higher than that of a control group of nitroglycerin and isosorbide dinitrate.

Description

technical field [0001] The invention belongs to the application of traditional Chinese medicine preparations, and relates to the application of an oxymatrine injection antiangina drug. Background technique [0002] Angina pectoris is a common symptom of coronary heart disease, which is caused by rapid and transient ischemia pre-hypoxia of the myocardium. The main manifestations are left chest and retrosternal compression pain or colic, which is a frequently-occurring disease and a common disease of elderly cardiovascular diseases in my country. It seriously affects the quality of life of the elderly in our country in their later years, and is also a factor leading to myocardial infarction and sudden death. Mainly inject chemical drug nitroglycerin, isosorbide dinitrate preparations, Chinese medicine tablets and pills at present, but it is still not ideal enough. [0003] Oxymatrine ( oxymatrine ) also known as matrine and matrine ( matrine ), which is the active ingredi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4375A61K9/08A61M5/00A61P9/10
Inventor 韩在刚张玉明
Owner BEIHUA UNIV
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