Automatic-medicine-carrying long-time transdermal-delivery and sampling device

Abstract

The invention provides an automatic-medicine-carrying long-time transdermal-delivery and sampling device. The automatic-medicine-carrying long-time transdermal-delivery and sampling device comprises a base plate. Microneedles are manufactured on the front face of the base plate. A storage cavity for storing medicine or sampled matter is formed in the back face of the base plate. Delivering channels communicated with the storage cavity and the front face of the base plate are formed in roots of the microneedles. At least one inwards-concave flow guide groove is formed along the surface of each microneedle. The flow guide grooves are communicated with the delivering channels and at least extend from the bottom of the storage cavity in the back face of the base plate downwards to the depth portions, punctured by the microneedles, of the skin. The automatic-medicine-carrying long-time transdermal-delivery and sampling device further comprises a cover plate with which the storage cavity in the back face of the base plate is covered. The cover plate is a flexible cover plate, or the cover plate is a rigid cover plate. A control device for medicine releasing or body fluid / blood sampling is integrated in the cover plate. By means of the automatic-medicine-carrying long-time transdermal-delivery and sampling device, medicine delivering time can be prolonged, and the number of medicine delivering times can be decreased; in addition, the limitation of the low epidermis penetration rate is broken through, and the medicine delivering effect is better.

Description

Technical field [0001] The invention relates to a medical appliance, in particular to a transdermal drug delivery and sampling device. Background technique [0002] At present, the microneedle device has begun to enter the application stage. The microneedle punctures the skin epidermis, and the drug applied on the microneedle is administered through the punctured epidermis. However, the currently used microneedle device has some shortcomings; [0003] One of the disadvantages is that the active drug is smeared on the surface of the microneedle of the microneedle device. The microneedle is only coated with a small amount of drug. When piercing the skin for administration, the duration of the action is not enough, and it cannot be transdermal for a long time. ; [0004] The second disadvantage is that after the microneedle pierces the skin epidermis, the skin epidermis is self-repairing. After a short period of time, the skin epidermis is closed by the fluid channel at the puncture si...

AI Technical Summary

Problems solved by technology

[0003] One of the disadvantages is that the active drug is smeared on the surface of the microneedle of the microneedle device, and the microneedle is only coated with a small amount of drug. When puncturing the skin for administration, the persistence of the effect is not enough, and long-term transdermal administration cannot be performed. ;

[0004] The second disadvantage is that after the microneedle punctures the skin epidermis, due to the self-repair of the skin epidermis, after a short period of time, the fluid channel at the punctured part of the skin epidermis is closed, and the surface-applied drugs cannot be released slowly for a long time

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