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Application of conjugated linoleic acid or derivatives thereof to prepare alcohol metabolism promoter

A technology of conjugated linoleic acid and derivatives, applied in the field of biomedicine, can solve the problems of lack of adequate awareness of physical discomfort and inconspicuous perception of physical reactions, shortening the duration, reducing blood alcohol concentration, and improving dehydrogenase activity. Effect

Inactive Publication Date: 2016-03-16
DALIAN JINZANG COMML & TRADING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Judging from the survey data on drinking status, the drinking control situation of Chinese drinking population is not ideal, the physical reaction caused by excessive drinking is not obvious, and the physical discomfort caused by excessive drinking is not fully aware

Method used

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  • Application of conjugated linoleic acid or derivatives thereof to prepare alcohol metabolism promoter
  • Application of conjugated linoleic acid or derivatives thereof to prepare alcohol metabolism promoter
  • Application of conjugated linoleic acid or derivatives thereof to prepare alcohol metabolism promoter

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] According to the test operation in 5.1, 0.2ml / 10g amount, intragastric administration of 14.5% conjugated linoleic acid solution (5% sodium carboxymethyl cellulose to help dissolve), the dose is 2.7g conjugated linoleic acid / kg body weight .

Embodiment 2

[0044] According to the experimental operation process of 5.1, the amount of 0.2ml / 10g was given to mice with 15% conjugated linoleic acid glyceride solution (5% carboxymethylcellulose sodium to help dissolve), and the dose was 3g conjugated linoleic acid glyceride Esters / kg body weight (equivalent to 2.7g conjugated linoleic acid / kg body weight).

Embodiment 3

[0046] According to the experimental operation process of 5.1, the amount of 0.2ml / 10g was given to mice with 7.5% conjugated linoleic acid glyceride solution (5% carboxymethylcellulose sodium to help dissolve), and the dose was 2g conjugated linoleic acid glyceride Esters / kg body weight (equivalent to 1.9g conjugated linoleic acid / kg body weight).

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Abstract

The invention belongs to the field of biological medicines, and discloses application of conjugated linoleic acid or derivatives thereof to prepare an alcohol metabolism promoter, an alcohol dehydrogenase activity promoter or alcohol-effect dispelling preparations. The invention provides the novel purpose of conjugated linoleic acid or derivatives thereof (especially conjugated linoleic acid glyceride), and animal experiments prove that the conjugated linoleic acid or derivatives thereof possess efficacies of improving liver alcohol dehydrogenase activity, accelerating concentration reduction of alcohol in blood and shortening drunk symptom lasting time.

Description

technical field [0001] The invention belongs to the field of biomedicine and relates to new applications of conjugated linoleic acid or derivatives thereof. More specifically, it relates to the new application of conjugated linoleic acid or its derivatives in the preparation of alcohol metabolism accelerators or anti-alcohol preparations. Background technique [0002] my country's wine culture has a long history, and there is a saying that there is no feast without wine. In 2007, the monitoring data of the National Center for Disease Control and Prevention showed that the drinking rate of men and women rose to 55.6% and 15.0%, and the proportion of excessive drinking among men was 62.7% and that of women was 51.0%. The 2007 Survey Report on People's Healthy Drinking in 25 Provinces of China shows that the primary reason for drinking alcohol in my country is to establish and maintain interpersonal relationships, mainly including communication with friends and customer servic...

Claims

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Application Information

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IPC IPC(8): A61K31/201A61K31/231A61P39/02
CPCA61K31/201A61K31/231
Inventor 王冬莉
Owner DALIAN JINZANG COMML & TRADING CO LTD
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