Detector device for blood culture bottle with colorimetric sensor

A technology of colorimetric sensor and blood culture, applied in the field of detector device of blood culture bottle with colorimetric sensor

Active Publication Date: 2018-01-12
BIO MERIEUX INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

These effects will not affect the reading, but will appear as a drift in the response of the system

Method used

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  • Detector device for blood culture bottle with colorimetric sensor
  • Detector device for blood culture bottle with colorimetric sensor
  • Detector device for blood culture bottle with colorimetric sensor

Examples

Experimental program
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Embodiment Construction

[0042] The present invention involves the use of a secondary LED as a light source to compensate for non-emulsion sensor (LES) variations to the optical system. image 3 A block diagram of the optical configuration is shown. This configuration was used to test vial 1 with colorimetric LES 2 contained within vial 1 . The arrangement includes a sensor LED 4, an IR reference LED 10 and a photodetector 5 generating an intensity signal. Both LEDs 4 and 10 are as image 3 Shown at a 45 degree angle relative to the bottom surface of the bottle. By means of a control circuit that selectively and alternately activates the sensor LED and the reference LED ( Figure 7 42) to continuously measure the reflectance of the bottom of the bottle and the LES 2. For example, a sensing or red LED 4 is switched on and the reflected signal is measured by a photodetector 5 . The sensor LED 4 then goes out. The reference LED 10 is then illuminated, and the same photodetector 5 measures the refle...

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PUM

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Abstract

The present invention relates to a detector device for a blood culture bottle with a colorimetric sensor. A detector device for a blood culture bottle containing a colorimetric sensor that is subject to a color change due to a change in pH or CO2 of a sample medium within the blood culture bottle is disclosed. The detector arrangement includes a sensor LED to illuminate the colorimetric sensor, a reference LED to illuminate the colorimetric sensor, a control circuit for selectively and alternately activating the sensor LED and the reference LED, and a photodetector. The photodetector measures reflectance from the colorimetric sensor during selective and alternate illumination of the colorimetric sensor using the sensor LED and the reference LED, and produces an intensity signal. The reference LED is chosen to have an illumination peak wavelength such that the intensity signal from the photodetector illuminated by the reference LED is affected by the color change of the colorimetric sensor.

Description

[0001] This application is a divisional application of the application dated July 19, 2011, the application number is 201180035365.2, and the title of the invention is "Detector device for blood culture bottle with colorimetric sensor". [0002] Cross References to Related Applications [0003] This application claims the benefit of US Provisional Patent Application No. 61 / 400,001, filed July 20, 2010, entitled "Detector Arrangement for BloodCulture Bottles With Colorimetric Sensors." Background technique [0004] Vials for culturing blood for the presence of microorganisms and associated apparatus for analyzing such vials in a non-invasive manner are known in the art and described in the patent literature. See US Pat. The vials and apparatus of the patents listed above were successfully commercialized by the present assignee under the trademark BacT / ALERT. [0005] The bottles described in these blood culture instruments utilize a colorimetric sensor placed in the bottom of...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/34G01N21/78
CPCC12M41/26C12M41/34C12M41/36G01N21/78G01N21/80G01N21/783G01N2021/3181G01N21/3151G01N33/84G01N2201/127
Inventor 布拉德福德·G·克莱
Owner BIO MERIEUX INC
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