Nano antibacterial gel for trauma nursing and preparation method thereof

A nano and trauma technology, applied in antibacterial drugs, medical preparations containing active ingredients, pharmaceutical formulations, etc., can solve problems such as difficulty in screening antibiotics for traumatic infections, drugs that cannot achieve ideal curative effects, and unsatisfactory curative effects. The effect of bioavailability, promoting wound healing, improving absorption and availability

Inactive Publication Date: 2016-04-20
刘婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the widespread use of antibiotics, drug-resistant strains have gradually increased. Traumatic infections are sometimes not caused by a single bacteria. Therefore, it is difficult to screen out effective antibiotics for traumatic infections, resulting in unsatisfactory curative effects and long course of disease.
And existing traditional Chinese medicine care agent can only be used for the lighter person of wound inflammation, if there are serious cases such as ulcer, above-mentioned medicine all can not reach ideal curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A nano antibacterial gel for trauma care, prepared by main materials and auxiliary materials by weight components, the main materials include by weight: 24 parts of thorns, 22 parts of grass pepper, Hemeng 21 parts of leaves, 20 parts of schisandra cotyledons, 20 parts of winter jasmine, 20 parts of ferns, 6 parts of Melaleuca, 5 parts of melon seed lotus, 4 parts of dog seedlings, 3 parts of edelweiss, 2 parts of Dibacao , 1 part of Wukou tree, 1 part of snow lotus, 1 part of rock sugar grass, 1 part of betel oil, 1 part of nano powder of chicken hen feather, 1 part of nano powder of sea moon shell, 0.02 part of crape myrtle leaf extract, 0.01 part of catalpa leaf extract parts; the auxiliary materials include by weight parts: 20 parts of gel matrix, 0.3 parts of surfactant, and 0.1 part of dispersant.

[0040] Wherein, the particle size of the nano-powder of chicken feather feather and the nano-powder of sea moon shell is 1nm, and the drug can be crushed to the nanome...

Embodiment 2

[0048] A nano antibacterial gel for trauma care, prepared by main materials and auxiliary materials by weight components, the main materials include by weight: 37 parts of thorns, 34 parts of grass pepper, Hemeng 33 parts of leaves, 30 parts of schisandra leaves, 28 parts of winter jasmine, 25 parts of fern, 9 parts of Melaleuca, 7.5 parts of melon seed lotus, 5.5 parts of dog seedlings, 4 parts of edelweiss, 3.5 parts of white grass , 3 parts of Wukoushu, 2 parts of snow lotus, 2 parts of rock sugar grass, 1.5 parts of betel oil, 1.5 parts of chicken hen feather nano powder, 1.5 parts of sea moon shell nano powder, 0.04 part of crape myrtle leaf extract, 0.015 part of catalpa leaf extract ; The auxiliary materials include by weight: 27.5 parts of gel matrix, 0.65 parts of surfactant, and 0.25 parts of dispersant.

[0049] Wherein, the particle size of the nano-powder of chicken feather and sea moon shell is 150nm, and the pulverization of the drug to the nano-scale can promot...

Embodiment 3

[0057] A nano antibacterial gel for trauma care, prepared by main materials and auxiliary materials by weight components, the main materials include by weight: 50 parts of thorns, 46 parts of grass pepper, Hemeng 45 parts of leaves, 40 parts of schisandra cotyledons, 36 parts of winter jasmine, 30 parts of fern, 12 parts of Melaleuca, 10 parts of melon seeds, 7 parts of dog seedlings, 5 parts of edelweiss, 5 parts of white grass , 5 parts of Wukou tree, 3 parts of snow lotus, 3 parts of rock sugar grass, 2 parts of betel oil, 2 parts of chicken hen feather nano powder, 2 parts of sea moon shell nano powder, 0.06 part of crape myrtle leaf extract, 0.02 part of catalpa leaf extract parts; the auxiliary materials include by weight parts: 35 parts of gel matrix, 1 part of surfactant, and 0.4 part of dispersant.

[0058] Wherein, the particle size of the said nano-powder of chicken feather and sea moon shell is 300nm, and the pulverization of the medicine to the nanometer level can...

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Abstract

The invention discloses nano antibacterial gel for trauma nursing and a preparation method thereof. The nano antibacterial gel for trauma nursing is prepared from Smilax ferox Wall. Ex Kunth, all-grass of shiny peperomia, leaves of common aeschynomene herb, schisandra glaucescens diels leaves, winter jasmine leaves, Mecodiummicrosorum (V.d.B.) Ching., the bark of cajeput, Crotalaria yunnanensis Franch., calystegia hederacea, edelweiss, viola diffusa, Tarenna attenuata (Voigt) Hutch., lanatechead saussurea herb with flowers, sweet broomwort herb, betel leaf oil, chicken's tail feather nano powder, Placuna placenta (Linnaeus) shell nano powder, crape myrtle leaf extract and catalpa leaf extract. The nano antibacterial gel is a nano antibacterial gel preparation prepared through the advanced pharmaceutical preparation technology according to the theory of traditional Chinese medicine in combination with clinical experience through reasonable selection and compatibility of Chinese herbal medicine ingredients, the effects of resisting bacteria and diminishing inflammation, dispelling wind and eliminating dampness and restraining sores and promoting tissue regeneration are achieved, wound inflection is effectively avoided, and wound healing is promoted. The medicine is processed to be in a nanoscale, the absorption and utilization rate of the medicine is increased, and the medicine effect is enhanced. The nano antibacterial gel is a pure traditional Chinese medicine preparation, and is free of side effects and high in safety.

Description

technical field [0001] The invention relates to the technical field of nursing medication, in particular to a nano antibacterial gel for wound care and a preparation method thereof. Background technique [0002] Whether it is at work or in life, trauma will inevitably occur. Many people lack the common sense of wound care, resulting in wound infection, fever and other symptoms, which is not conducive to wound healing. If the patient's wound has typical symptoms of wound infection such as redness and swelling, generally speaking, for wound infection in this case, use normal saline to repeatedly clean the wound to remove foreign matter from the wound, and apply povidone iodine to the wound for anti-inflammation. At the same time, some anti-inflammatory drugs can be taken orally as adjuvant treatment. However, for some severe purulent wound infections, in addition to the above cleaning work for the wound, it is also necessary to remove foreign matter and necrotic tissue in th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/90A61K9/06A61P31/04A61P17/02A61K35/618
CPCA61K36/90A61K9/0014A61K9/06A61K35/57A61K35/618A61K36/12A61K36/185A61K36/28A61K36/285A61K36/35A61K36/39A61K36/48A61K36/61A61K36/63A61K36/67A61K36/74A61K36/80A61K36/86A61K36/896A61K47/38A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 刘婷
Owner 刘婷
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