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Cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals and preparation method of cholesterol-lowering and antithrombotic traditional Chinese medicine composition

An anti-thrombotic and hypolipidemic technology, applied in drug combinations, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., can solve problems such as increased blood urea nitrogen, adverse effects on the human body, and impaired liver function.

Inactive Publication Date: 2016-04-20
江苏平光信谊(焦作)中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] At present, there are many kinds of lipid-lowering products on the market, mainly western medicines of statins, which are quick to take effect, but hyperlipidemia is a chronic disease that requires long-term medication, and long-term use of western medicines is likely to cause liver damage. Elevated alanine aminotransferase, elevated urea nitrogen, adverse effects on the human body, and prone to drug dependence

Method used

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  • Cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals and preparation method of cholesterol-lowering and antithrombotic traditional Chinese medicine composition
  • Cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals and preparation method of cholesterol-lowering and antithrombotic traditional Chinese medicine composition
  • Cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals and preparation method of cholesterol-lowering and antithrombotic traditional Chinese medicine composition

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Effect test

Embodiment 1

[0039] A traditional Chinese medicine composition for lowering blood fat, antithrombosis, warming meridians and activating collaterals, the raw materials include 10 parts of Rhizoma Chuanxiong, 8 parts of Safflower, 15 parts of Astragalus, 7 parts of Panax notoginseng, 4 parts of Guizhi, 10 parts of Radix Paeoniae Rubra, and Radix Puerariae by weight. 2 parts, 9 parts of turmeric, 3 parts of woody fragrance, 10 parts of hawthorn, 0.15 parts of borneol, 55 parts of sucrose, and 10 parts of dextrin.

[0040] The preparation method of the above-mentioned traditional Chinese medicine composition for lowering blood fat, antithrombotic, warming meridians and activating collaterals comprises the following steps:

[0041] S1. Preparation of extract: take Chuanxiong, safflower, astragalus, red peony root, kudzu root, cassia twig, turmeric, woody incense, and hawthorn and mix them evenly to obtain a mixture; add water to the mixture, adjust the steam pressure to 0.3MPa, decoct three time...

Embodiment 2

[0045] A traditional Chinese medicine composition for lowering blood fat, antithrombosis, warming meridians and activating collaterals, the raw materials include 15 parts by weight of Rhizoma Chuanxiong, 4 parts of Safflower, 25 parts of Astragalus, 5 parts of Panax notoginseng, 8 parts of Guizhi, 5 parts of Radix Paeoniae Rubra, and Radix Puerariae 5 parts, 3 parts of turmeric, 6 parts of woody fragrance, 3 parts of hawthorn, 0.35 parts of borneol, 25 parts of sucrose, and 35 parts of dextrin.

[0046] The preparation method of the above-mentioned traditional Chinese medicine composition for lowering blood fat, antithrombotic, warming meridians and activating collaterals comprises the following steps:

[0047] S1. Preparation of extract: take Chuanxiong, safflower, astragalus, red peony root, kudzu root, cassia twig, turmeric, woody, hawthorn and mix to obtain a mixture; add water to the mixture, adjust the steam pressure to 0.2MPa, decoct three times, Filter the filtrate, co...

Embodiment 3

[0051] A traditional Chinese medicine composition for lowering blood fat, antithrombosis, warming meridians and activating collaterals, the raw materials include 12 parts by weight of Rhizoma Chuanxiong, 7 parts of Safflower, 16 parts of Radix Astragali, 6 parts of Panax notoginseng, 6 parts of Guizhi, 7 parts of Radix Paeoniae Rubra, Pueraria Radix 4 parts, 7 parts of turmeric, 3 parts of woody fragrance, 7 parts of hawthorn, 0.25 parts of borneol, 50 parts of sucrose, and 15 parts of dextrin.

[0052] The preparation method of the above-mentioned traditional Chinese medicine composition for lowering blood fat, antithrombotic, warming meridians and activating collaterals comprises the following steps:

[0053] S1. Preparation of extract: take Chuanxiong, safflower, astragalus, red peony root, kudzu root, cassia twig, turmeric, woody incense, and hawthorn and mix them evenly to obtain a mixture; add water to the mixture, adjust the steam pressure to 0.28MPa, and decoct three ti...

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Abstract

The invention discloses a cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals. The cholesterol-lowering and antithrombotic traditional Chinese medicine composition is prepared from the following raw materials: ligusticum wallichii, flos carthami, astragalus membranaceus, panax notoginseng, cassia twig, a red peony root, puerarin, curcuma aromatic, costustoot, hawthorn, borneol, cane sugar and dextrin. The invention further discloses a preparation method of the cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals. The method comprises the following steps: (S1) preparing an extract: mixing taken ligusticum wallichii, flos carthami, astragalus membranaceus, red peony root, puerarin, cassia twig, curcuma aromatica, costustoot and hawthorn evenly to obtain a mixture, adding water to the mixture, decocting the mixture for three times, filtering and taking filtrate, merging the filtrate of three times and concentrating the filtrate to obtain the extract, wherein the relative density of the extract is 1.32-1.35g / ml; (S2) preparing dry panax notoginseng powder; and (S3) pelletizing: mixing the borneol, the ethanol, the dextrin, the cane sugar, the extract obtained in the step (S1) and the dry panax notoginseng powder obtained in the step (S2) evenly, preparing a soft material, pelletizing, drying, granulating, and mixing the mixture evenly to obtain the cholesterol-lowering and antithrombotic traditional Chinese medicine composition for warming channels and activating collaterals.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for lowering blood fat, resisting thrombus, warming meridians and activating collaterals and a preparation method thereof. Background technique [0002] Hyperlipidemia is one of the common diseases of middle-aged and elderly people, and it is also a disease that has attracted much attention and seriously affected the normal life of middle-aged and elderly people. General adult fasting serum total cholesterol exceeds 5.72mmol / L, triglyceride exceeds 1.70mmol / L, can be diagnosed as hyperlipidemia, and total cholesterol in the range of 5.2-5.7mmol / L is called marginally elevated. [0003] The clinical manifestations of hyperlipidemia mainly include two aspects: 1. Xanthoma caused by lipid deposition in the dermis; 2. Atherosclerosis caused by lipid deposition in the vascular endothelium, resulting in coronary heart dis...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61K47/36A61P3/06A61P9/10A61K31/045
CPCA61K36/9066A61K9/1652A61K31/045A61K36/236A61K36/258A61K36/285A61K36/286A61K36/481A61K36/488A61K36/54A61K36/65A61K36/71A61K36/734A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 王康林马婕
Owner 江苏平光信谊(焦作)中药有限公司
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