Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure

A pleural cavity, breathing work technology, applied in respirator, drug equipment, pressure sensor, etc., can solve problems such as the decline in the popularity of commercial equipment

Active Publication Date: 2016-04-27
KONINKLJIJKE PHILIPS NV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

As a result, routine monitoring of WOB via the Campbell plot has not been accepted as routine clinical practice at the bedside, and the popularity of commercially available devices employing this plot has gradually declined

Method used

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  • Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure
  • Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure
  • Non-invasive estimation of intra-pleural pressure and/or computation of work of breathing based on a non-invasive estimation of intra-pleural pressure

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Experimental program
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Embodiment Construction

[0028] A method for non-invasively determining intrapleural pressure and / or using said non-invasively determined intrapleural pressure and / or other non-invasively determined intrapleural pressure to determine a measure of work of breathing (WOB) in a subject is described below .

[0029] figure 1 A physiological parameter determination device 102 is illustrated in combination with a ventilator 104, which may alternatively be combined with invasive and non-invasive applications. Controller 106 controls ventilator 104 .

[0030] In the illustrated embodiment, device 108 provides an air path from ventilator 104 to the subject or target. In the case of invasive ventilation, the device 108 can be an endotracheal tube, a tracheostomy tube, etc., including a "Y" connector. In the non-invasive case, device 108 can be a nasal mask, full face mask, etc., including any tubing between ventilator 104 and the mask.

[0031] Airway pressure sensor 112 measures pressure at the airway, and...

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Abstract

A method includes obtaining a first physiological parameter indicative of a non-invasively measured airway pressure of a subject, obtaining a second physiological parameter indicative of a non-invasively measured air flow into the lungs of the subject, and estimating a third physiological parameter indicative of an intra-pleural pressure of the subject based on the first and second physiological parameters and generating a signal indicative thereof. An other method includes obtaining a first physiological parameter indicative of a non-invasively estimated intra-pleural pressure of a subject, determining a second physiological parameter indicative of a lung volume of the subject that is based on a third physiological parameter indicative of a non-invasively measured air flow into the lungs of the subject, and determining a work of breathing based on the first and second physiological parameters and generating a signal indicative thereof.

Description

technical field [0001] The following generally relates to determining a physiological state of a subject, and more particularly to estimating a subject's intrapleural pressure based on non-invasively determined parameters and / or calculating a subject's work of breathing measure based on the noninvasively estimated subject's intrapleural pressure. Background technique [0002] Work of breathing (WOB) is defined as the effort exerted by the respiratory muscles to breathe. When a patient is connected to a mechanical ventilator, WOB can be divided into two components: 1) the physiological work of breathing, which is expended against the resistive and elastic pressures of the respiratory system, and 2) the Inner tube and ventilator) imposed work of breathing. The total WOB was calculated with each breath and normalized with respect to tidal volume to give Joules / L. [0003] Real-time measurement of WOB in mechanically ventilated patients can be used to assess whether a patient ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/03A61B5/087A61M16/00A61B5/085
CPCA61B5/037A61B5/038A61B5/085A61B5/087A61B5/4836A61M16/00A61M2016/0027A61M2016/0033A61M2210/105A61M2230/46A61M2230/65A61M16/026A61B5/091A61B5/7278A61B2562/0247
Inventor N·W·什巴特A·阿尔巴内塞S·W·海德N·卡拉莫列赫科斯A·J·塞沃
Owner KONINKLJIJKE PHILIPS NV
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