Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

3D-printed counter-current chromatography separation column for and chromatographic instrument

A countercurrent chromatography and 3D printing technology, which is applied in the field of countercurrent chromatography separation columns and chromatographs, can solve the problems of limited development of countercurrent chromatographic columns, difficult innovation of pipeline structure, easy damage of pipelines, etc., to increase the interaction of solutions Force and mixing strength, improved distribution efficiency, and improved separation efficiency

Inactive Publication Date: 2016-06-01
SHANDONG ANALYSIS & TEST CENT
View PDF11 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The countercurrent chromatography separation column with this structure is limited by commercial polytetrafluoroethylene tubes, and it is difficult to innovate in the pipeline structure. limit
At the same time, due to the direct friction between the PTFE pipeline and the support during the winding process, the pipeline is easily damaged and leaks. In addition, when the pipeline is relatively long, the volume of the countercurrent chromatographic separation column after winding will be very large. Big

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • 3D-printed counter-current chromatography separation column for and chromatographic instrument
  • 3D-printed counter-current chromatography separation column for and chromatographic instrument
  • 3D-printed counter-current chromatography separation column for and chromatographic instrument

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The structure of the present invention is as figure 2 , image 3 As shown in the figure, the 3D printed countercurrent chromatography separation column has an integrated structure of the pipeline and the support column by 3D printing technology.

[0029] Further, the countercurrent chromatographic separation column 1 is a columnar structure, and a cylindrical protrusion coaxial with the columnar structure is provided at the center of the top and bottom of the columnar structure, and a columnar structure and two cylindrical protrusions are provided along the center of the cylindrical protrusion. The central axis perforation 2 in the center of the shaped protrusion is provided with central axis fixing screw perforations 3, 6, 7, 8, 9 on the sides of the two cylindrical protrusions; the sample inlet 4 is provided on the cylindrical protrusion at the top, There are multiple circles of cylindrical channels 10 used to replace the original pipelines in the columnar structure...

Embodiment 2

[0035] A chromatograph, the countercurrent chromatographic separation column adopts the 3D printed countercurrent chromatographic separation column designed in Example 1.

[0036] Aiming at the technical difficulties existing in conventional countercurrent chromatography separation columns, the present invention develops a countercurrent chromatography separation column based on 3D printing, which can print out tube shapes of any structure through drawing software, and then directly print them through 3D printing technology, and because the tube The road and the supporting column are integrally formed by 3D printing technology, so when the length of the pipeline is as long as that of the prior art, the volume of the separation column of the present invention is obviously smaller than that of the prior art.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a 3D-printed counter-current chromatography separation column and a chromatographic instrument. The counter-current chromatography separation column is of a columnar structure integrally formed based on the 3D printing technology, multiple circles of columnar channels used for conveying samples and communicated end to end are formed in the columnar structure, one end of each columnar channel serves as a sample inlet, the other end of each columnar channel serves as a sample outlet, and burrs are arranged on the inner wall of each columnar channel at intervals. The pipeline of the 3D-printed counter-current chromatography separation column is not likely to leak liquid, and the 3D-printed counter-current chromatography separation column can withstand a wide temperature range in the use process.

Description

technical field [0001] The invention relates to a countercurrent chromatographic separation column used in a chromatograph, and specifically discloses a 3D printed countercurrent chromatographic separation column and a chromatograph. Background technique [0002] Conventional countercurrent chromatography separation columns are composed of polytetrafluoroethylene tubes and pipeline supports, for example: the countercurrent chromatography separation columns disclosed in patents with patent numbers 02250372.2, 89221310.8, 201020002148.6, 201120031345.5, 201220647532.4, which include a pipeline support 1 -1 and the polytetrafluoroethylene pipeline 1-2 wound on the pipeline support body 1-1, and the outer layer of the pipeline is fixed with glue, and a plastic or metal shell is placed on the outermost pipeline friction. The countercurrent chromatography separation column with this structure is limited by commercial polytetrafluoroethylene tubes, and it is difficult to innovate ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/60
CPCG01N30/6052
Inventor 王岱杰王晓高乾善崔莉纪文华井凤
Owner SHANDONG ANALYSIS & TEST CENT
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com