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Application of dihydromyricetin in cosmetic and speckle-removing products

A technology of dihydromyricetin and products, which is applied in the field of natural medicine application, can solve the problems of low water solubility of dihydromyricetin, oxidation of dihydromyricetin, and weak skin action, so as to promote rapid healing, enhance Bacteriostasis, contact chance reduction effect

Active Publication Date: 2018-08-10
长沙爱扬医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, dihydromyricetin and white polysaccharides are used alone in each product. Since dihydromyricetin is not highly water-soluble and viscous, it is not very effective to apply directly to the skin, and dihydromyricetin is more likely to appear Oxidation and other issues

Method used

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  • Application of dihydromyricetin in cosmetic and speckle-removing products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: the preparation method of Baiji polysaccharide

[0031] Crush 100kg of dry white powder, directly add 200L of petroleum ether and stir for 20min, then let it stand for 1 hour to separate and remove the upper layer solution containing petroleum ether to obtain Precipitation I; add 250L of 80% ethanol aqueous solution to Precipitation I, stir and extract for 70min , let it stand for 60 minutes, and removed the upper layer solution containing ethanol by layers to obtain Precipitation Ⅱ. Add 300L of water to the precipitate II, stir and heat to 80°C, keep warm for 40min, centrifuge at 5000rpm for 20min to obtain the supernatant, and remove the precipitate. Concentrate the supernatant under reduced pressure at 50-65°C to 1 / 25 of its original volume, then add 95% ethanol until the final concentration reaches more than 75%, ethanol precipitation for 10-20h, and filter once with a 0.22μm ceramic membrane to obtain The filter residue is white and polysaccharide pr...

Embodiment 2

[0032] Embodiment 2: the preparation of beauty spot removing product

[0033] Take 200mL of 35°C distilled water and add 8 grams of r-aminobutyric acid. After dissolving, add 10 grams of chitosan, then add 80 grams of white and polysaccharide, and finally add 8 grams of dihydromyricetin, and accelerate the dissolution through ultrasonic treatment. Vacuum-dried to reduce the water content to 20%, to obtain 115 grams of cosmetic and speckle-removing products, which were stored in vacuum packaging for future use. The content of dihydromyricetin detected by HPLC in 1 gram of samples was 6.92%.

Embodiment 1

[0035] Take 200mL of 35°C distilled water and add 80 grams of Baiji polysaccharide. After the Baiji polysaccharide is completely dissolved, add 8 grams of dihydromyricetin. It cannot be completely dissolved under the action of ultrasonic waves. It needs to be heated to 80°C to dissolve and then vacuum dried. Its water content is reduced to 20%, and the obtained product is 104 grams, and adopts vacuum packaging to preserve for future use, takes 1 gram sample and detects that the content of dihydromyricetin is 7.34% by HPLC method.

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Abstract

The invention relates to a composite formula obtained through compatibility of dihydromyricetin and bletilla striata polysaccharide for beautifying and freckle removing. According to the composite formula, 8 g gamma-aminobutyric acid is added to 200 mL distilled water which is 30-35 DEG C, 10 g chitosan is added after dissolution, 80 g bletilla striata polysaccharide is added, finally 8 g dihydromyricetin is added, deoxidation and dissolution acceleration are achieved through ultrasonic treatment, water content is reduced to 25% through vacuum drying, and vacuum packaging is conducted for storage and use. The solubility of dihydromyricetin can be remarkably promoted by gamma-aminobutyric acid and bletilla striata polysaccharide, the film forming feature of the product can be guaranteed by chitosan, and the stability of dihydromyricetin is facilitated.

Description

Technical field: [0001] The invention relates to the application of dihydromyricetin in cosmetic and speckle-removing products, and belongs to the technical field of natural medicine application. Background technique [0002] Bletilla striata, also known as Bletilla striata, also known as Bletilla striata, is a perennial herb belonging to the family Orchidaceae, with a plant height of 18-60cm. Baiji pseudobulb is a commonly used traditional Chinese medicine, which has good effects of stopping bleeding and astringent, reducing swelling and promoting granulation. It is used internally to treat pulmonary tuberculosis hemoptysis, bronchiectasis hemoptysis, gastric ulcer hematemesis, hematuria, and blood in the stool; external use is used to treat traumatic bleeding, burns, and chapped hands and feet. In recent years, the research on the chemical constituents of Bletilla radicis has focused on the bibenzyl, dihydrophenanthrene and biphenanthrene compounds in bulbs. A series of a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/44A61K8/49A61K8/73A61Q17/00A61Q19/00A61Q19/02A61K31/352A61K31/715A61K31/197A61K31/722A61P31/02A61P17/02A61P17/00
CPCA61K8/44A61K8/498A61K8/73A61K8/736A61K31/197A61K31/352A61K31/715A61K31/722A61K2800/782A61Q17/005A61Q19/00A61Q19/02A61K2300/00
Inventor 王婧
Owner 长沙爱扬医药科技有限公司
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