Mold for preparing microneedle chip and preparation method thereof

A chip and microneedle technology, applied in the direction of microneedles, needles, medical equipment, etc., can solve the problems of complex preparation process, high calcination temperature, high energy consumption, etc., achieve good micro-perfusion effect, simple process method, and operability sex high effect
CN105643839BActive Publication Date: 2018-01-12GUANGZHOU NEWORLD PHARMA CO LTD
3 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GUANGZHOU NEWORLD PHARMA CO LTD
Publication Date
2018-01-12

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a mold for preparing a microneedle chip and a preparation method thereof, belonging to the technical field of transdermal drug delivery preparations. The mold includes: a female mold, on which several cavities arranged to form an array matching the shape of the needle body of the microneedle chip are arranged, each cavity has a pouring inlet and an exhaust port, and the pouring inlet opens on the One side surface of the female mold is located at the needle base end of the cavity, the exhaust port is opened on the other side surface of the female mold and is located at the needle tip of the cavity, and the female mold has a plurality of The surface of the exhaust port forms an exhaust surface; and a gas-permeable film covers the exhaust surface for preventing liquid from penetrating and allowing gas to permeate. The mold can discharge gas while trapping liquid, and has better micro-perfusion effect. When using the mold to prepare microneedle chips, it is unnecessary to perform centrifugation and other processes that are difficult to realize in industrial production, making it possible to industrially produce high-quality microneedle chips.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the technical field of transdermal drug delivery preparations, in particular to a mold for preparing a microneedle chip and a preparation method thereof. Background technique

[0002] Microneedle transdermal drug delivery technology is a new type of transdermal drug delivery method. Its biggest technical advantage is that it can penetrate the natural barrier of the skin, the stratum corneum, to form microscopic pores, thereby accelerating the absorption rate of externally applied drugs. Because the dermis and intradermal nerves are not injured, there is little or no pain. In particular, soluble microneedles have the advantages of good biological adaptability, no risk of needle retention in the body, rapid dissolution, patients can administer the drug themselves, and no cross-infection of needles can cut off the disease transmission route. attention.

[0003] However, due to the small size of the soluble microneedle itself, th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More