Feed composition and application thereof to preparation of animal feed additive
A technology of composition and derivatives, which is applied in the field of preparation of animal feed additives, can solve the problems of drug residues, use restrictions or prohibitions, and drug resistance that transmits threats to human health.
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Embodiment 1
[0089] Example 1: Study on the inhibitory activity of different butyric acid derivatives against colistin sulfate-sensitive Escherichia coli.
[0090] The in vitro minimum inhibitory concentration (MIC) of different butyric acid derivatives against colistin sulfate-sensitive Escherichia coli was tested by the test tube double dilution method, and the results are shown in Table 1. It can be seen from Table 1 that all test strains are sensitive to colistin sulfate and all test butyric acid derivatives have weak inhibitory activity on test strains (Table 1).
[0091] The in vitro minimum inhibitory concentration (MIC, ppm) of butyric acid derivatives of table 1 to colistin sulfate sensitive Escherichia coli
[0092]
Embodiment 2
[0093] Example 2: Study on the inhibitory activity of different myristic acid derivatives against Clostridium perfringens.
[0094] The in vitro minimal inhibitory concentration (MIC) of virginiamycin and myristic acid derivatives against Clostridium perfringens was tested by the test tube double dilution method, and the results are shown in Table 2. It can be seen from Table 2 that all test strains are sensitive to virginiamycin, and all test myristic acid derivatives have similar inhibitory activity to test strains as virginiamycin.
[0095] The minimum inhibitory concentration (MIC, ppm) of table 2 myristic acid derivatives to Clostridium perfringens in vitro
[0096]
Embodiment 3
[0097] Embodiment 3: the application effect of calcium butyrate and calcium myristate in weaning pig feed
[0098] 180 28-day-old weaned pigs with an average body weight of 7.61kg and Dudu long-term hybrid lean piglets with similar body weight were divided into 9 groups as shown in Table 3, with 20 pigs in each group. After each group added different test additives to the conventional creep feed (without any drug feed additive, zinc oxide and high copper preparations), they had free access to food and water, and the average daily feed intake of the test pigs in each test group within 10 days was counted. (ADF), average daily gain (ADG), feed compensation and diarrhea rate. The results are shown in Table 3. As can be seen from Table 3, calcium butyrate can achieve the effect of feed antibiotic colistin sulfate 20ppm when the dosage of calcium butyrate in the feed is 400ppm, and the control and production performance of the animal diarrhea rate The change of calcium myristate p...
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