Feed composition and application thereof to preparation of animal feed additive

A technology of composition and derivatives, which is applied in the field of preparation of animal feed additives, can solve the problems of drug residues, use restrictions or prohibitions, and drug resistance that transmits threats to human health.

Inactive Publication Date: 2016-07-06
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long-term use of high-dose inorganic zinc or inorganic copper feed additives is toxic to animals and inhibits growth; and the abuse of feed antibiotics also leads to the emergence of microbial resistance, drug residues, and the transmission of drug resistance, posing threats to human health
The emergence of these problems has led to the restriction or prohibition of the use of traditional feed additives in animal farming

Method used

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  • Feed composition and application thereof to preparation of animal feed additive
  • Feed composition and application thereof to preparation of animal feed additive
  • Feed composition and application thereof to preparation of animal feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] Example 1: Study on the inhibitory activity of different butyric acid derivatives against colistin sulfate-sensitive Escherichia coli.

[0090] The in vitro minimum inhibitory concentration (MIC) of different butyric acid derivatives against colistin sulfate-sensitive Escherichia coli was tested by the test tube double dilution method, and the results are shown in Table 1. It can be seen from Table 1 that all test strains are sensitive to colistin sulfate and all test butyric acid derivatives have weak inhibitory activity on test strains (Table 1).

[0091] The in vitro minimum inhibitory concentration (MIC, ppm) of butyric acid derivatives of table 1 to colistin sulfate sensitive Escherichia coli

[0092]

Embodiment 2

[0093] Example 2: Study on the inhibitory activity of different myristic acid derivatives against Clostridium perfringens.

[0094] The in vitro minimal inhibitory concentration (MIC) of virginiamycin and myristic acid derivatives against Clostridium perfringens was tested by the test tube double dilution method, and the results are shown in Table 2. It can be seen from Table 2 that all test strains are sensitive to virginiamycin, and all test myristic acid derivatives have similar inhibitory activity to test strains as virginiamycin.

[0095] The minimum inhibitory concentration (MIC, ppm) of table 2 myristic acid derivatives to Clostridium perfringens in vitro

[0096]

Embodiment 3

[0097] Embodiment 3: the application effect of calcium butyrate and calcium myristate in weaning pig feed

[0098] 180 28-day-old weaned pigs with an average body weight of 7.61kg and Dudu long-term hybrid lean piglets with similar body weight were divided into 9 groups as shown in Table 3, with 20 pigs in each group. After each group added different test additives to the conventional creep feed (without any drug feed additive, zinc oxide and high copper preparations), they had free access to food and water, and the average daily feed intake of the test pigs in each test group within 10 days was counted. (ADF), average daily gain (ADG), feed compensation and diarrhea rate. The results are shown in Table 3. As can be seen from Table 3, calcium butyrate can achieve the effect of feed antibiotic colistin sulfate 20ppm when the dosage of calcium butyrate in the feed is 400ppm, and the control and production performance of the animal diarrhea rate The change of calcium myristate p...

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Abstract

The invention provides a feed composition and application thereof to preparation of an animal feed additive. A butyric acid derivative is selected from butyrate or butyric ester, a myristic acid derivative is selected from myristate or myristic ester, and the optimal mass ratio of the butyric acid derivative to the myristic acid derivative is (4-1):1. The feed composition can serve as an animal growth accelerant, particularly can replace traditional animal growth accelerants such as feed antibiotic or a high-dose zincic preparation or copper preparation to be applied to animal breeding industry, is a novel safe animal feed additive, is suitable for livestock, poultry, aquaculture animals and the like and has wide market prospects.

Description

Technical field: [0001] The invention belongs to the field of animal feed additives, in particular to a feed composition containing butyric acid derivatives and myristic acid derivatives and its application in the preparation of animal feed additives. Background technique: [0002] Animal feed is currently a necessary animal basal diet to replace traditional raw agricultural products in animal farming. People often hope that animals can grow healthily and efficiently with the least consumption of feed in the shortest time. In order to achieve this purpose, feed additives with various functions are added to feed during feed processing to prepare functional feed. Among them, feed antibiotics, zinc oxide or copper sulfate are commonly used feed additives in the past to improve animal production performance and prevent animal diseases. However, the long-term use of high-dose inorganic zinc or inorganic copper feed additives is toxic to animals and inhibits growth; and the abus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/105A23K20/24A23K20/22
CPCA23K20/10
Inventor 彭险峰
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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