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External preparation for treating skin pruritus caused by leukoplakia, scar and tinea and preparation method thereof

A technology for vulvar leukoplakia and external preparations, which is applied in the direction of medical preparations containing active ingredients, skin diseases, pharmaceutical formulas, etc. It can solve the problems of significant side effects, achieve significant curative effect, simple preparation process, and small side effects

Inactive Publication Date: 2018-08-07
李旭红 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many kinds of skin itching caused by leukoplakia, scars and skin ringworm, but most of them are hormone or antibiotic drugs with significant side effects

Method used

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  • External preparation for treating skin pruritus caused by leukoplakia, scar and tinea and preparation method thereof
  • External preparation for treating skin pruritus caused by leukoplakia, scar and tinea and preparation method thereof
  • External preparation for treating skin pruritus caused by leukoplakia, scar and tinea and preparation method thereof

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Embodiment Construction

[0017] The present invention will be further described below in conjunction with specific embodiments, rather than limiting the present invention.

[0018] 1. The synergistic effect of acetic acid and salicylic acid against fungi.

[0019] In vitro bacteriostatic test was used to observe the pathogenicity of acetic acid and salicylic acid on six common pathogens including Trichophyton rubrum, Candida albicans, Epidermophyton flocculus, Trichophyton gypsumiform, Microsporum lanoiformis and Microsporum gypsumiformis The minimum inhibitory concentration method (drug-based method) of fungus: mix the medicine of 10 different concentrations with Sabouraud culture medium, after disinfection, plant six kinds of common pathogenic fungi such as Trichophyton rubrum on the medicine culture medium, in Cultivate and observe in a constant temperature incubator (25-28° C.) for 2 weeks, repeat each drug more than twice, and take the lowest drug dilution concentration at which no secondary fung...

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Abstract

The invention discloses an external preparation for treating skin itch caused by leukoplakia vulvae, scar and skin tinea and a preparation method thereof. The external preparation is prepared from the following components in parts by mass: 4-8 parts of glacial acetic acid, 3-6 parts of salicylic acid, 0.5-2 parts of antioxidant, 10-50 parts of solubilizing and skin penetration enhancer, 5-20 parts of alcohol solubilizer and the balance of distilled water based on 100 parts in total, wherein the pH value is 2.4-3.0. With the itch-relieving and antifungal functions, the external preparation is mainly used for treating the skin itch caused by leukoplakia vulvae, scar and skin tinea and has the advantages of easily available raw materials, easiness and convenience in preparation and application, no hormone or antibiotics, safety without toxin, few side effects, remarkable curative effect and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine for skin diseases and its preparation, and specifically relates to an external preparation for treating skin itching caused by genital leukoplakia, scars and skin ringworm and a preparation method thereof, which is formulated with glacial acetic acid and salicylic acid. Background technique [0002] Leukoplakia is a common skin disease in gynecology. The formation of this disease is mostly related to the dystrophy of the nerves and blood vessels in the deep connective tissue of the vulva, which leads to lesions on the skin covering it. Grooves, often symmetrical, the skin of the ward is thickened like leather, raised with folds, generally without atrophy and adhesion. A scar is the mark left after a sore or wound has healed. Since the scar tissue in the proliferative stage is very sensitive to the physical and chemical factors of the surrounding environment, whenever there is a change in the ou...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/60A61K31/19A61K9/08A61P17/04A61P15/02
CPCA61K9/08A61K31/19A61K31/60A61K2300/00
Inventor 李旭红夏爱斌冯志明
Owner 李旭红
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