Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Green synthesis method for tributyrin for high-content feed

A tributyrin and green synthesis technology, which is applied in the preparation of carboxylic acid esters, chemical instruments and methods, and the preparation of organic compounds, can solve the problems of high price and uneconomical storage of butyryl chloride, and achieve favorable storage , easily decomposed effect

Inactive Publication Date: 2016-07-27
上海旭牧联生物科技有限公司
View PDF4 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, the price of butyryl chloride is high, uneconomical and not easy to store

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Green synthesis method for tributyrin for high-content feed

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) Add 28g (0.3mol) of glycerin and 400g (1.5mol) of butyric acid with a content of 99.5% to a 1000ml four-necked reaction bottle (with electric stirring, thorn-type rectification column and a nitrogen tube inserted into the bottom of the bottle), and then add SO 4 2- / ZrO 2 -TiO 2 Solid superacid catalyst 0.6g, start stirring.

[0034] (2) The oil bath is heated to 100°C, and an appropriate flow rate of nitrogen gas is introduced from the bottom. The water containing butyric acid was distilled into the receiving bottle through the thorn rectification tube and the condenser, and the temperature was slowly raised to 148°C as the water continued to evaporate until there was no distillate. 19 ml of water containing 18.3% butyric acid was distilled off.

[0035] (3) After cooling down to 80°C, continue heating, turn on a small amount of nitrogen and small bubbles will emerge, distill the remaining excess butyric acid under reduced pressure, and collect butyric acid wi...

Embodiment 2

[0038] Process is with embodiment 1, and butyric acid uses the butyric acid 311g that embodiment 1 reclaims and the neobutyric acid of 100g99.5%, and solid superacid catalyst uses the recovery catalyst of embodiment 1. The product was light yellow and transparent, with a yield of 96.4% relative to glycerin, a tributyrin content of 95.6%, and a moisture content of 68ppm.

Embodiment 3

[0040] Process is with embodiment 1, uses SO 4 2- / Fe 2 o 3 -TiO 2 Solid superacid catalyst instead. Obtain light yellow transparent product, relative yield of glycerin is 96.4%, tributyrin content 95.8%, moisture content 72ppm.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of fine chemical synthesis, and particularly relates to a green synthesis method for tributyrin for a high-content feed. According to the method, a super strong acid catalyst is utilized; with nitrogen as a protecting agent and water-carrying agent, the tributyrin is obtained through rectification and reduced pressure distillation; the purity reaches 95% or over; the moisture content is smaller than 100ppm; the super strong acid catalyst can be simply filtered and separated from a product, and does not need alkali washing, washing and drying processes; no wastewater and waste solid are generated; the catalyst can be repeatedly used; the water solution of which the butyric acid content is smaller than or equal to 20% obtained by distillation in the reaction process can be applied to synthesis of a feed additive sodium butyrate; and no less than 80% of butyric acid can be recycled by reduced pressure distillation to return to first-step synthesis.

Description

technical field [0001] The invention belongs to the technical field of fine chemical synthesis, and in particular relates to a green synthesis method of high-content feed tributyrin. Background technique [0002] Glyceryl butyrate is the esterified product of butyric acid and glycerol, which can be used as a feed additive. It can not only solve the problem that butyric acid is difficult to add as an oily liquid, but also overcome the disadvantage of butyric acid having an unpleasant smell. After butyrin enters the animal intestine, it is decomposed into butyric acid and glycerol under the action of intestinal lipase. Butyric acid has the functions of supplying cell energy, promoting the growth and development of epithelial tissue, repairing the intestinal barrier structure, antibacterial and anti-inflammatory, etc. It can protect the intestinal health of animals, promote animal growth and reduce feeding costs. [0003] Compared with glyceryl monobutyrate and glyceryl dibuty...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07C69/30C07C67/08
CPCC07C67/08C07C69/30
Inventor 李恒章邱春明黄亚霖郑根华杨建香
Owner 上海旭牧联生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com