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Experimental method of Penthorum chinense Pursh on effect of normal sexual functions of male rats

An experimental method and technology for catching yellow grass, applied in the experimental field of the effect of catching yellow grass on the normal sexual function of male rats, can solve the problems of weakening male sexual function and the like

Inactive Publication Date: 2016-08-10
SOUTHWEST MEDICAL UNIVERISTY
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern studies have shown that the various active ingredients in C. chinensis have protective effects on liver damage, and have a certain therapeutic effect on hepatitis A, hepatitis B, and chronic active hepatitis. However, it is rumored that C. chinensis has the side effect of weakening male sexual function.

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  • Experimental method of Penthorum chinense Pursh on effect of normal sexual functions of male rats
  • Experimental method of Penthorum chinense Pursh on effect of normal sexual functions of male rats
  • Experimental method of Penthorum chinense Pursh on effect of normal sexual functions of male rats

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Embodiment Construction

[0025] In order to further understand the content, features, and effects of the present invention, the following embodiments are exemplified and described in detail below with the accompanying drawings.

[0026] See figure 1 :

[0027] Experimental animals, SD rats, weighing 180±20g, male and female, purchased from the Experimental Animal Center of Southwest Medical University, production license number: SCXK (川) 2013-17, use license number: SCXK (川) 2013-065 .

[0028] Experimental environment, the experiment was carried out in the SPF experimental center of Southwest Medical University. The animals were caged (the cage volume was 20cm×39cm×54cm), and 5 animals of the same sex were kept in each cage. The basic feed is the complete pellet feed for experimental mice, and the animals in each group are fed routinely with free drinking water. The bottom bedding of the cage is wood shavings, which shall be disinfected and dried before use; the cage shall be used after disinfection. On...

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Abstract

The invention discloses an experimental method for the influence of C. chinensis on the normal sexual function of male rats. The rats are randomly divided into a blank control group, a positive control group of 15 mg / kg Viagra and three dosage groups of C. kg, 1.0g crude drug / kg, 2.0g crude drug / kg, continuous gavage for 14 days, the test was carried out to determine the effect of C. chinensis on the mating ability of rats, the weight of sexual organs, the erectile function of penis, and the sperm of normal male rats. The research results of the present invention suggest that Viagra may improve the mating ability of male rats, but three doses of C. chinensis were administered orally for 28 days continuously, and the behavior of the animals was as usual, and the general condition was good. The mating ability, sexual organ index, penile erectile function, and sperm survival rate of animals in each experimental group had no obvious promoting or inhibiting effects, and there was no significant difference compared with the blank control group. Therefore, Chahuangcao has no obvious effect on the normal sexual function of male rats, and it is safe for long-term application.

Description

Technical field [0001] The invention belongs to the field of animal experiments, and in particular relates to an experimental method for the influence of Huangcao on the normal sexual function of male rats. Background technique [0002] The scientific name of Penthorum chinense Pursh, also known as water willow and water adenophora, is the aerial part of the genus Root of Saxifragae (saxifraganceae). It is a kind of Miao family medicinal material produced by Gulin in Luzhou, Sichuan. It was first published in "Saving Famine in Materia Medica" in the Ming Dynasty, and now published in "Dictionary of Traditional Chinese Medicine", "National Chinese Herbal Medicine Collection", "Sichuan Traditional Chinese Medicine History", "Hunan Medicine History", "Inner Mongolia Botanical Medicine History", etc. The whole herb is used as medicine in the folks. It is warm in nature, sweet in taste and non-toxic. It has the effects of clearing heat and detoxifying, promoting blood circulation and ...

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Application Information

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IPC IPC(8): A61K49/00
CPCA61K49/0004
Inventor 税丕先刘明华李婷刘中飞孙琴朱烨
Owner SOUTHWEST MEDICAL UNIVERISTY
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