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Applications, as well as preparation method and preparation of vernonia amygdalina extract

A technology of Vernonia almonds and extracts, which are used in health care products, preparation of Vernonia almonds extracts, Vernonia almonds extracts for preventing and treating gout, preparation of medicines for treating hyperuricemia or gout, and application fields in food, It can solve the problems of many side effects, poor compliance, unfavorable long-term medication, etc., and achieve the effects of convenient administration, low cost, and reducing xanthine oxidase activity.

Inactive Publication Date: 2016-09-07
HEBEI LIN YITANG MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are mainly two ways to reduce uric acid clinically: inhibiting uric acid production or increasing uric acid excretion. Drugs such as allopurinol, colchicine, benzbromarone, and probenecid are the most common anti-gout drugs, and their clinical application is increasing. Increased, to a certain extent relieved the local symptoms of gout, but most of them treat the symptoms rather than the root cause, and have more side effects, poor compliance, unfavorable for long-term medication, and the case reports of adverse drug reactions caused are gradually increasing. Currently, it is safe, effective, There are few economical anti-gout drugs, so it is of great significance to find new anti-gout drugs, especially the development of preparations that lower uric acid and xanthine

Method used

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  • Applications, as well as preparation method and preparation of vernonia amygdalina extract
  • Applications, as well as preparation method and preparation of vernonia amygdalina extract
  • Applications, as well as preparation method and preparation of vernonia amygdalina extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Preparation of Vernonia almonds extract.

[0029] In this example, to prepare the extract of Vernonia amygdala, the raw material used is the dried leaves of Vernonia amygdala. First, the dried leaves of Vernonia amygdala are cleaned. Net impurities, foreign matter, insects, mildew and non-medicinal parts, to obtain qualified raw materials.

[0030] The specific preparation method of the extract of Vernonia amygdala in the present embodiment comprises the following process steps:

[0031] Step 1-1) Pulverizing, pulverizing Vernonia almonds into coarse powder, putting the dried leaves of Vernonia almonds into a pulverizer, and pulverizing them into coarse powder with a particle size of 10-30 mesh.

[0032] Step 1-2) ethanol extraction, put the almond vernonia coarse powder in a multifunctional extraction tank, according to the mass ratio of ethanol and almond vernonia coarse powder as 4:1, add ethanol with a volume fraction of 90%, first use ethanol After soaking for 0....

Embodiment 2

[0036] Preparation of Vernonia almonds extract.

[0037] In this example, to prepare the extract of Vernonia amygdala, the raw material used is the dried leaves of Vernonia amygdala. First, the dried leaves of Vernonia amygdala are cleaned. Net impurities, foreign matter, insects, mildew and non-medicinal parts, to obtain qualified raw materials.

[0038] The specific preparation method of the extract of Vernonia amygdala in the present embodiment comprises the following process steps:

[0039] Step 1-1) Pulverizing, pulverizing Vernonia amygdala into a coarse powder, putting the dried leaves of Vernonia amygdala into a pulverizer, and pulverizing it into a coarse powder with a particle size of 20-50 mesh.

[0040] Step 1-2) ethanol extraction, put the almond vernonia coarse powder in a multifunctional extraction tank, according to the mass ratio of ethanol and almond vernonia coarse powder as 8:1, add ethanol with a volume fraction of 70%, first use ethanol After soaking fo...

Embodiment 3

[0044] Preparation of Vernonia almonds extract.

[0045] In this example, to prepare the extract of Vernonia amygdala, the raw material used is the dried leaves of Vernonia amygdala. First, the dried leaves of Vernonia amygdala are cleaned. Net impurities, foreign matter, insects, mildew and non-medicinal parts, to obtain qualified raw materials.

[0046] The specific preparation method of the extract of Vernonia amygdala in the present embodiment comprises the following process steps:

[0047]Step 1-1) Pulverizing, pulverizing Vernonia amygdala into a coarse powder, putting the dried leaves of Vernonia amygdala into a pulverizer, and pulverizing it into a coarse powder with a particle size of 40-60 mesh.

[0048] Step 1-2) ethanol extraction, put the almond vernonia coarse powder in a multifunctional extraction tank, according to the mass ratio of ethanol and almond vernonia coarse powder is 10:1, add ethanol with a volume fraction of 20%, first use ethanol After soaking fo...

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Abstract

The invention discloses applications of vernonia amygdalina extract used for preventing and treating gout, and further discloses a preparation method of the vernonia amygdalina extract, and a preparation containing the vernonia amygdalina extract. The vernonia amygdalina extract provided by the invention has the efficacies of decreasing blood uric acid, and reducing the activity of xanthine oxidase, and has an obvious effect for preventing and treating gout disease.

Description

technical field [0001] The present invention relates to the technical field of natural product extraction, in particular to a preparation method of Vernonia amygdala extract, and the use of Vernonia amygdala extract in the prevention and treatment of gout and in the preparation of medicines, health care products and foods for the treatment of hyperuricemia or gout. in the application. Background technique [0002] Gout is a metabolic disease caused by the body producing too much uric acid or reducing the excretion of uric acid, and the concentration of uric acid in the blood continues to increase, resulting in the deposition of urate crystals in joints and other tissues. sign. Gout has gradually become an important clinical problem that endangers the health of our people, and hyperuricemia is the most important basis and direct cause of gout. [0003] In recent years, research on gout and hyperuricemia at home and abroad has continued to deepen. Research results have shown...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P19/06A23L33/105
CPCA61K36/28A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 林飞武孔增科田春雨李继安刘凤洲
Owner HEBEI LIN YITANG MEDICAL CO LTD
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