Sterilization repairing cleaning agent, preparation method and application thereof

A technology of cleaning agent and silver ion antibacterial agent, applied in the field of medicine, can solve the problems of high irritation, acidity change, discoloration, etc., and achieve the effect of high antibacterial efficiency and stable antibacterial efficiency.

Active Publication Date: 2016-11-16
广州洁康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Not only that, whether the existing formula technology adopts traditional aldehyde acid antibacterial agents (formaldehyde, benzoic acid), chlorine preparations (triclosin, chlorhexidine acetate, chlorine dioxide, hypochlorous acid), or relatively novel Both nano-silver antibacterial agents and colloidal silver antibacterial agents have the defects of unsatisfactory antibacterial effect and poor stability (discoloration, acidity change)
[0006] In addition, in the prior art, cleaning agents used for the vagina and vulva or

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A bactericidal repair cleaning agent, comprising the following components by mass percentage: 0.3% chlorhexidine acetate, 15% surfactant, 3% glycerin, 0.1% citric acid, honeysuckle extract, wild chrysanthemum extract, horse Purslane extract and peppermint extract are each 0.1%, silver ion antibacterial agent is 1%, and the rest is purified water. Among them, the surfactant is composed of APG2000, CAB-35, and 6501 with a mass ratio of 5:3:0.5, that is, alkyl glucoside (APG2000), cocamidopropyl betaine (CAB-35) and The mass ratio of coconut oil fatty acid diethanolamide (6501) is 5:3:0.5.

[0028] The formula of this embodiment 1 (gynecological antibacterial lotion), the bactericidal rate is increased to more than 90% from 70% of the prior art (without adding silver ion antibacterial agent), and the effect of relieving itching and removing peculiar smell is compared to the common one in the prior art Gynecological wash time reduced by 10%, i.e. to 2 minutes.

[0029] Un...

Embodiment 2

[0031] A bactericidal repair cleaning agent, comprising the following components by mass percentage: 0.1% chlorhexidine acetate, 10% surfactant, 5% glycerin, 0.15% citric acid, honeysuckle extract, wild chrysanthemum extract, horse Purslane extract and peppermint extract are each 0.5%, silver ion antibacterial agent is 6%, and the rest is purified water. Among them, the surfactant is composed of APG2000, CAB-35, and 6501 with a mass ratio of 5:3:0.5, that is, alkyl glucoside (APG2000), cocamidopropyl betaine (CAB-35) and The mass ratio of coconut oil fatty acid diethanolamide (6501) is 5:3:0.5.

[0032] Present embodiment 2 formula (sanitary care lotion), chlorhexidine acetate, plant extract, silver ion bactericide act together, and its bactericidal rate increases greatly, has added chlorhexidine acetate, plant extract and silver ion antibacterial agent, Its sterilization rate can reach more than 90%. The antipruritic and odor-removing time is shortened to 90 seconds; what i...

Embodiment 3

[0035]A bactericidal repair cleaning agent, comprising the following components by mass percentage: 8% surfactant, 6% glycerin, 0.25% citric acid, honeysuckle extract, wild chrysanthemum extract, purslane extract, peppermint extract 1% each, silver ion antibacterial agent 10%, and the rest is pure water. Among them, the surfactant is composed of APG2000, CAB-35, and 6501 with a mass ratio of 5:3:0.5, that is, alkyl glucoside (APG2000), cocamidopropyl betaine (CAB-35) and The mass ratio of coconut oil fatty acid diethanolamide (6501) is 5:3:0.5.

[0036] The formula (antipruritic and detoxification lotion) in this example 3 does not add chlorhexidine acetate, only silver ion antibacterial agent and medicinal and edible plant extracts, and the performance of the cleaning agent is better synergistically improved: the sterilization rate reaches 99%. , Multiple irritation tests on mucous membranes and skin show that this lotion is non-irritating, and the time for relieving itching...

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PUM

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Abstract

The invention relates to the technical field of medicine, in particular to a sterilization repairing cleaning agent, a preparation method and application. The cleaning agent is prepared from, by mass, 5-15% of a surface active agent, 3-8% of glycerinum, 0.1-0.3% of citric acid, 0.1-3% of a honeysuckle extract, 0.1-3% of a wild chrysanthemum flower extract, 0.1-3% of a purslane extract, 0.1-3% of a mint extract, 0-0.3% of chlorhexidine acetate and the balance a silver ion antibacterial agent and water, wherein the consumption of the silver ion antibacterial agent enables the concentration of silver ions in the cleaning agent to be 0.25-5 ppm. The surface active agent is alkyl glucoside, coconut oil oleamide propyl dimethylamine ethyl ester and coconut oil fatty oil diethanol amide. The cleaning agent is efficient in sterilization, mild, safe and capable of being placed stably for a long time and has the repairing function of vagina mucosa, skin and scalp.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a sterilizing and repairing cleaning agent, a preparation method and an application thereof. Background technique [0002] Researchers at home and abroad have extensively screened fungicides according to the purpose of sterilization and the characteristics of disinfection objects, but no ideal antibacterial agent has been found so far. Aldehyde and acid antibacterial agents (formaldehyde, benzoic acid) have a wide bactericidal spectrum, but are highly toxic, corrosive, and irritating to the vaginal mucous membrane and skin; chlorine preparations (triclosin, chlorhexidine acetate, dioxide Chlorine, hypochlorous acid) have low effective concentration, fast action speed and stable properties, but are easily affected by organic matter, acid, alkali and other physical and chemical factors, and are also more irritating to vaginal mucosa and skin. [0003] Therefore, inorganic antibac...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/19A61K8/362A61K8/43A61Q5/02A61Q15/00A61Q17/00A61Q19/10A61K36/534A61P15/02A61P17/04A61P31/02A61K31/155A61K33/38
CPCA61K8/19A61K8/362A61K8/43A61K8/97A61K9/0034A61K31/155A61K33/38A61K36/185A61K36/287A61K36/355A61K36/534A61Q5/02A61Q15/00A61Q17/005A61Q19/10A61K2300/00
Inventor 叶符材
Owner 广州洁康医药科技有限公司
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