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Pharmaceutical composition for treating diabetic constipation and preparation method thereof

A composition and diabetes technology, applied in the direction of drug combination, pharmaceutical formula, heterocyclic compound active ingredients, etc., can solve the problem of large dosage

Inactive Publication Date: 2016-11-16
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For mice with complete tumor regression, tumor cells were inoculated after 1-6 months, and no tumor grew. The extract was given by intraperitoneal injection, intravenous injection, and gavage, and the growth of tumors could be inhibited at a certain dose. However, the effect of gavage is worse than that of intraperitoneal injection and intravenous injection, and the dosage is also large.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the pharmaceutical composition for the treatment of diabetes constipation and preparation method thereof

[0033] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetes and constipation are: 2800g of safflower, 2300g of lantern flower, 4200g of Polyporus, 1000g of clam grass, 1400g of goat's milk, 66g of cobalt dilinoleate, hyoscyamine hydrobromide 90g;

[0034] Preparation:

[0035] (1) Take safflower, lantern flower, polyporus, clam grass, goat's milk, cobalt dilinoleate, and hyoscyamine hydrobromide according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 38% by weight as a solvent, Warm soaking and extracting at 30°C, the number of extractions is 9 times, each extraction time is 45 hours, and the amount of solvent used each time is 45 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and the extrac...

Embodiment 2

[0038] Embodiment 2: the pharmaceutical composition for the treatment of diabetic constipation and its preparation method

[0039] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetes and constipation are: 2750g of safflower, 2350g of lantern flower, 4150g of polyporus, 1050g of clam grass, 1350g of goat's milk, 72g of cobalt dilinoleate, hyoscyamine hydrobromide 85g;

[0040] Preparation:

[0041] (1) Take safflower, lantern flower, polyporus, clam grass, goat's milk, cobalt dilinoleate, and hyoscyamine hydrobromide according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 38% by weight as a solvent, Warm soaking and extracting at 30°C, the number of extractions is 9 times, each extraction time is 45 hours, and the amount of solvent used each time is 45 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and the extract A ...

Embodiment 3

[0044] Embodiment 3: the pharmaceutical composition for the treatment of diabetes constipation and preparation method thereof

[0045] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating diabetes and constipation are: 2850g of safflower, 2250g of lantern flower, 4250g of polyporus, 950g of clam grass, 1450g of goat's milk, 62g of cobalt dilinoleate, hyoscyamine hydrobromide 95g;

[0046] Preparation:

[0047] (1) Take safflower, lantern flower, polyporus, clam grass, goat's milk, cobalt dilinoleate, and hyoscyamine hydrobromide according to the ratio of raw materials, mix them evenly, and use ethanol with a concentration of 38% by weight as a solvent, Warm soaking and extracting at 30°C, the number of extractions is 9 times, each extraction time is 45 hours, and the amount of solvent used each time is 45 times the total weight of the raw material drug, and filtered to obtain medicinal residue A and extract A, and the ext...

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PUM

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Abstract

The invention discloses a medicine composition for treating diabetes and constipation and a preparation method thereof. Hyoscyamine is the raw material medicine, which is prepared by proportioning, and can be made into various dosage forms according to the conventional preparation process, and has remarkable curative effect in treating diabetes and constipation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating diabetes and constipation and a preparation method thereof. Background technique [0002] Diabetes mellitus is a relatively common chronic disease clinically, which can affect multiple system organs. At present, there are many methods for clinical treatment of diabetic constipation, but there are few methods to completely cure the disease, which only improve the symptoms of patients. Therefore, in-depth exploration of the methods for treating diabetic constipation has important clinical value. [0003] Safflower: [source] is the whole herb of the leguminous plant milk vetch. Collected in spring and summer, washed, used fresh or sun-dried. [Original form] Milk vetch is an annual herb. Stems erect or prostrate, 10-40cm high. Odd-pinnate compound leaves; stipules ovate, with hairs on top; leaflets 7-13,...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61P1/10A61P3/10A61K31/46A61K31/201
CPCA61K36/481A61K31/46A61K33/24A61K36/07A61K36/185A61K36/30A61K36/45A61K2236/333A61K2236/39A61K2236/55
Inventor 庞大坤孔倩倩
Owner JINAN XINGYI MEDICAL TECH
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