Application of bear gall powder in preparation of medicament capable of preventing and treating transhepatic arterial chem otherapy and embolization (TACE) failed back surgery syndrome of primary hepatic carcinoma patients

A technology for primary liver cancer and chemoembolization, applied in the field of medicine, can solve the problems of lack of preventive and therapeutic measures, and achieve the effects of aggravating liver cell damage, improving liver function damage, and promoting liver function recovery.

Inactive Publication Date: 2017-01-04
福建归真堂药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The occurrence of post-embolism syndrome is a multi-factor and multi-link process, but there is still a lack of effective and comprehensive preventive and therapeutic measures for it in clinic

Method used

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  • Application of bear gall powder in preparation of medicament capable of preventing and treating transhepatic arterial chem otherapy and embolization (TACE) failed back surgery syndrome of primary hepatic carcinoma patients
  • Application of bear gall powder in preparation of medicament capable of preventing and treating transhepatic arterial chem otherapy and embolization (TACE) failed back surgery syndrome of primary hepatic carcinoma patients

Examples

Experimental program
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Embodiment 1

[0019] Example 1 Clinical study of bear bile powder in prevention and treatment of syndrome after hepatic arterial chemoembolization in patients with primary liver cancer

[0020] (1) Material method

[0021] 1 clinical data

[0022] Patients with primary liver cancer who were hospitalized in the Department of Traditional Chinese Medicine Oncology of Changhai Hospital from June 2015 to July 2016 were selected, and the diagnostic criteria were based on the clinical diagnostic criteria in the "Primary Liver Cancer Diagnosis and Treatment Standards 2011 Edition" promulgated by the Ministry of Health. A total of 107 patients were included, including 82 males and 25 females, aged 54.9±8.3 years old, who were divided into the control group and the Xiongdan capsule group by random number method. There were 56 cases in the control group, 44 males and 12 females, aged 55.7±8.5 years; 51 cases in the Xiongdan capsule group, 38 males and 13 females, aged 54.1±8.1 years old.

[0023] Di...

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Abstract

The invention relates to new medical application of bear gall powder, namely an application of bear gall powder in preparation of a medicament capable of preventing and treating transhepatic arterial chem otherapy and embolization (TACE) failed back surgery syndrome of primary hepatic carcinoma patients. The invention has the advantages that clinical research indicates that bear gall powder is capable of obviously improving the TACE failed back surgery syndrome of primary hepatic carcinoma patients, reducing the glutamicoxalo acetictransaminase level, protecting the liver function and reducing the inflammatory factor level for the first time, and has the application prospect of preventing and treating transhepatic arterial chem otherapy and embolization (TACE) failed back surgery syndrome of primary hepatic carcinoma patients.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a new medicine application of bear bile powder. Background technique [0002] Transcatheter arterial chemoembolization (TACE) is currently the main method for the treatment of unresectable liver cancer. The common complication caused by TACE is liver injury after ischemia, which is one of the thorny problems in the treatment of liver tumors. The reason for this complication is not only the direct injury caused by the operation itself, but also the body's excessive stress response to trauma, ischemia and hypoxia, which may also be a very important factor that aggravates liver damage. In a sense, this complication is the excessive stress response of the body to trauma, ischemia and hypoxia, etc., resulting in the massive release of various cellular mediators including inflammatory factors, further aggravating liver damage, and even changing the systemic The functions of tissues ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/413A61P29/00A61P1/16
CPCA61K35/413
Inventor 陈志鸿许剑峰凌昌全程彬彬
Owner 福建归真堂药业股份有限公司
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