A pharmaceutical composition for increasing bone density and its preparation method

A technology for increasing bone density and composition, which is applied in the field of pharmaceutical composition for increasing bone density and its preparation, can solve problems such as increasing bone density, achieve increasing bone density, reduce the activity of tartrate-resistant acid phosphatase, and be easy to digest and absorb Effect

Active Publication Date: 2017-06-06
湖南知达医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Sodium vitamin C phosphate is a derivative of vitamin C. It is a new type of food additive. Vitamin C can be liberated by phosphatase enzymolysis in the body, and the unique physiological functions of vitamin C can be exerted. It can be used to prevent and treat scurvy and relieve white vitiligo. and other diseases, there is currently no relevant research showing that vitamin C phosphate sodium has the effect of increasing bone density

Method used

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  • A pharmaceutical composition for increasing bone density and its preparation method
  • A pharmaceutical composition for increasing bone density and its preparation method
  • A pharmaceutical composition for increasing bone density and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1 Preparation of pharmaceutical composition for increasing bone density and its granules

[0045] The pharmaceutical composition for increasing bone density in Example 1 of the present invention includes the following preparation materials in parts by weight: 3 parts of oyster, 1 part of malt, 2 parts of yam, 1 part of Poria cocos, 2 parts of jujube, 1 part of licorice, 1 part of Gallus gallus domesticus Servings, vitamin D 2 0.0000025 parts, 12 parts calcium gluconate, 20 parts isomalt oligosaccharides, 5 parts citric acid, 45 parts cyclodextrin.

[0046] Preparation of pharmaceutical composition:

[0047] (1) Take malt, yam, Poria, jujube, Gallus gallus domesticus and licorice, dry and pulverize, pass through an 80-mesh sieve, add 8 times the total weight of the medicinal materials and soak for 1 hour, reflux and extract twice, each time for 4 hours. Filter and retain the filter residue, combine the filtrate to obtain a water extract;

[0048] (2) Add 8 times the to...

Embodiment 2

[0053] Example 2 Preparation of pharmaceutical composition for increasing bone density and its granules

[0054] The pharmaceutical composition for increasing bone density in Example 2 of the present invention includes the following preparation materials in parts by weight: 6 parts by weight of oysters, 0.5 parts of malt, 4 parts of Chinese yam, 1 part of Poria cocos, 1 part of jujube, 0.5 parts of licorice, and Gallus gallus 2 Servings, vitamin D 2 0.000001 parts, 15 parts calcium gluconate, 15 parts glucose, 5 parts citric acid, 40 parts starch.

[0055] Refer to Example 1 for the preparation of the pharmaceutical composition.

[0056] Refer to Example 1 for the preparation of granules.

Embodiment 3

[0057] Example 3 Preparation of pharmaceutical composition for increasing bone density and its granules

[0058] The pharmaceutical composition for increasing bone density in Example 3 of the present invention includes the following preparation materials in parts by weight: 2 parts of oyster, 2 parts of malt, 1 part of Chinese yam, 3 parts of Poria cocos, 4 parts of jujube, 2 parts of licorice, 0.5 parts of Gallus gallus domesticus Servings, vitamin D 2 0.000005 parts, 5 parts calcium gluconate, 10 parts white sugar, 5 parts citric acid, 50 parts mannitol.

[0059] Refer to Example 1 for the preparation of the pharmaceutical composition.

[0060] Refer to Example 1 for the preparation of granules.

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Abstract

The invention belongs to the field of health products and in particular relates to a pharmaceutical composition for increasing bone density and a preparation method thereof. The pharmaceutical composition provided by the invention is prepared from the following raw materials in parts by weight: 2-6 parts of oysters, 0.5-2 parts of malt, 1-4 parts of Chinese yams, 1-3 parts of poria cocos, 1-4 parts of Chinese dates, 0.5-2 parts of liquorice, 0.5-2 parts of endothelium corneum gigeriae, 0.000001-0.000005 part of vitamin D2, 5-15 parts of calcium gluconate, 2-5 parts of sodium L-ascorbic-acid-2-phosphate, 1-4 parts of glutathione, 1-4 parts of phellinus igniarius fermented powder and 2-75 parts of auxiliary materials. The pharmaceutical composition provided by the invention has a good calcium supplementing effect, is rich in nutritional ingredients, safe and effective, convenient to take and applicable to being taken by children for a long time and can promote sustainable growth of the bone density.

Description

Technical field [0001] The invention belongs to the field of health products, and specifically relates to a pharmaceutical composition for increasing bone density and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic change in bone mass and bone tissue structure, accompanied by increased bone fragility and easily lead to fractures. It is characterized by the decrease in bone mass per unit volume, the degradation of bone microstructure, the thinning of bone density, and the small bone size. Featured by the decrease in the number of beams, the widening of the bone marrow cavity, the decrease of bone strength, and the susceptibility to fractures, it has gradually become a public health issue of increasing concern in countries around the world. [0003] Bone density is an important indicator for the diagnosis of osteoporosis and is used by the World Health Organization to define the diagnostic criteria for osteoporosis. Bone density refers to the b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61K38/06A61P19/10A61P3/02A61K31/191A61K31/592A61K31/661A61K35/57A61K35/618
CPCA61K31/191A61K31/592A61K31/661A61K35/57A61K35/618A61K36/07A61K36/076A61K36/484A61K36/725A61K36/8945A61K36/8998A61K38/06A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 卞国良李君佩赵振伟
Owner 湖南知达医药科技有限公司
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