117 results about "Calcium borogluconate" patented technology

The invention provides autologous platelet-containing plasma gel and a preparation method and application thereof, and relates to the technical field of biological medicine and tissue engineering.The preparation method comprises the following steps that peripheral venous blood of a patient is extracted and added into a centrifugal tube mixed with a sodium citrate anticoagulant; putting the centrifugal tube into a centrifugal machine for centrifuging, and taking upper-layer plasma; wherein the upper-layer plasma refers to plasma between the upper-layer liquid level and the lower-layer red blood cell layer by 1mm; the centrifugal speed ranges from 1300 r / min to 1700 r / min; the centrifugation time is 3-5 min; under a sterile condition, preparing a calcium gluconate / thrombin mixed solution; and dropping the calcium gluconate / thrombin mixed solution into the upper plasma, mixing, and solidifying to obtain the autologous platelet-containing plasma gel. After one-time centrifugation, upper-layer full-layer plasma is extracted, the volume of the prepared gel is far larger than that of a traditional method, the utilization rate of whole blood platelets and fibrinogen is close to 100%, and regeneration and repair of large-area tissue wounds can be met.

The invention relates to the field of calcium gluconate evaporative crystallization equipment, in particular to a crystallizing tank for calcium gluconate crystallization production and a using method thereof.The crystallizing tank comprises an evaporative crystallization tank body, the evaporative crystallization tank body comprises a tank body, a stirring and uniform heating assembly is arranged on the inner edge of the tank body, and an adaptive adjusting assembly is installed on one side of the stirring and uniform heating assembly; a crystal transfer assembly is arranged at the middle part in the tank body; the stirring and uniform heating assembly is used for stirring the to-be-crystallized solution in the tank body to uniformly disperse heat; the adaptive adjusting assembly is used for adaptively adjusting the stirring and heat uniformizing assembly according to the evaporation progress; according to the crystal stirring device, the situation that the stirring work is easily affected in the later period that the crystals are continuously accumulated at the bottom in the tank body and become high can be avoided, and meanwhile the situation that the crystals are likely to collide with a stirring component along with flowing of a solution, and consequently the crystals are broken can be effectively reduced.

The multi-layer structure platelet-rich plasma preparation tube comprises a vacuum blood collection tube body, a rubber plug is installed at the top end of the vacuum blood collection tube body, and a calcium gluconate solution layer is arranged at the bottom in the vacuum blood collection tube body. A separation gel layer II is arranged on the upper side of the calcium gluconate solution layer in the vacuum blood collection tube body, and a vitamin C solution layer is arranged on the upper side of the separation gel layer II in the vacuum blood collection tube body. The invention has the beneficial effects that through the design of the separation gel layer I and the separation gel layer II, the effective isolation of the vitamin C solution layer and the calcium gluconate solution layer from the ACDA solution layer before centrifugal separation is realized, chemical reaction or degradation is avoided, and a mixture of vitamin C and PRP is conveniently and quickly obtained through centrifugal operation after blood drawing, so that the blood drawing efficiency is improved. The method is used for tissue repair, regeneration and whitening, the operation process is simplified, and the product quality and safety are improved.

The invention relates to the technical field of preparation of cured beef, and discloses low-salt cured beef which comprises main materials and auxiliary materials in parts by mass as preparation raw materials, the main materials comprise fresh yellow cattle meat and compound salt, and the auxiliary materials comprise tea polyphenol, alanine, calcium gluconate and a kelp powder aqueous extract. The formula comprises 100 parts of fresh yellow cattle meat, 5 parts of compound salt, 0.1 part of tea polyphenol, 0.2 part of alanine, 0.5 part of calcium gluconate and 1 part of kelp powder aqueous extract. The method comprises the following steps: putting cleaned beef strips into a microwave oven, mixing 5% of compound salt with tea polyphenol, anthocyanin, rosemary extract, alanine and calcium gluconate in order to improve the pickling efficiency, adding 50 parts of clear water, and uniformly stirring to prepare a pickling solution; and cooling the fried cured beef to room temperature, packaging with a vacuum packaging bag, and carrying out ultrahigh pressure treatment (300MPa, 5 minutes) to replace irradiation, prolong the shelf life and retain the flavor, so that the method has the advantages of traditional flavor, prolonged shelf life, simple production process and the like.

The invention discloses a liquid chromatography method for measuring 5-hydroxymethylfurfural in a calcium gluconate and sodium chloride injection. The method comprises the following steps: measuring the calcium gluconate and sodium chloride injection as a test solution; weighing 5-hydroxymethylfurfural, and adding water to dilute the 5-hydroxymethylfurfural to form a reference solution; carrying out continuous sample introduction on the liquid chromatograph by using the reference substance solution to obtain a system applicability solution chromatogram; when the chromatogram of the applicable solution of the system meets the standard, measuring the test solution and the reference solution, respectively injecting the test solution and the reference solution into a liquid chromatograph, and recording the chromatograms; the content of 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection is obtained through a 5-hydroxymethylfurfural content calculation formula. The method has the advantages of strong specificity, high sensitivity, good precision, strong durability and the like, and can quantitatively detect 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection, so that the safety of clinical medication of the calcium gluconate and sodium chloride injection is improved.

The utility model relates to the technical field of glucose production, and discloses a device for mixing calcium gluconate, which comprises a bracket assembly, a stirring box assembly is arranged at the top of the bracket assembly, an adjusting bracket assembly is arranged at the bottom of the bracket assembly, a stirring main body assembly is arranged in the stirring box assembly, and a stirring main body is arranged in the stirring main body assembly. And the bottom of the stirring main body assembly is provided with a convenient discharge storage box assembly. The convenient discharge storage box assembly is mounted on the device, so that after the stirring work of the device is completed, the convenient discharge work can be performed after the stirring work is concentrated in the convenient discharge storage box assembly, and the problem that the internal adhesion condition is unclear during discharge can be avoided through the assembly.

The present invention belongs to the field of preparation of diabetes complication remission agents, and particularly relates to a combined preparation for improving microcirculation of diabetic foot and a preparation method thereof. Starting from platelet-rich plasma, the present invention obtains exosomes containing rich active substances such as growth factors through stimulation with calcium gluconate and the like, and loads protamine nanoparticles to obtain bioactive substances with strong antibacterial ability, which can resist the development process of diabetic foot ulcers. The present invention uses bioactive glass, hydroxyethyl cellulose and the like to stabilize the bioactive substances, prolong the in vitro lifespan of the bioactive substances, and modified carboxymethyl cellulose provides better biodegradation effect. The combined preparation prepared by the present invention has less cytotoxicity, better antibacterial effect, can promote wound healing quickly, and the microcirculation index shows that it can stimulate the change of foot blood flow and improve the condition of foot artery blockage, etc.

The application discloses a crystallization equipment applied to an enzyme method for preparing calcium gluconate, belonging to the technical field of crystallization equipment, which comprises a tank body, a liquid adding opening is arranged on the side wall of the tank body, a cylinder body is arranged in the tank body, a cleaning rod is arranged between the cylinder body and the inner wall of the tank body, the cleaning rod is used for cleaning the inner wall of the tank body and the outer wall of the cylinder body, a plurality of plug-in plates are slidably connected to the inner bottom wall of the cylinder body, and the plurality of plug-in plates are arranged in the solution. The plug-in plates, the inner wall of the tank body and the outer wall of the cylinder body can reduce the nucleation barrier of the solution surface, the melt solution can form crystal nuclei at the locations with unevenness, and the solution can form nuclei locally at a very small cooling degree, so that the crystallization efficiency is accelerated, and the nucleation barrier condition is created for the solute to preferentially nucleate, thereby reducing the nucleation time of the solute.

The present disclosure discloses a composition for hair growth comprising Larix europea wood extract, Camellia sinesis leaf extract, Pisum sativum sprout extract, Curcuma longa (Turmeric) callus conditioned media, Hamamelis virginiana (Witch Hazel), Rosmarinus officinalis Leaf Oil, Glycerin, Glycine, Zinc Chloride, Sodium Metabisulfite, Gluconolactone, Sodium Benzoate, Calcium Gluconate, Tetrasodium ethylenediaminetetraacetic acid (EDTA), Saccharide Isomerate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Propanediol, Biotinoyl Tripeptide- 1, Alpha Glucosyl Hesperidin, Caffeine, Hydrolyzed Pea Protein, Polyalkylene Glycol Mono Butyl Ether, Acrylates / C 10-30 Alkyl Acrylate Crosspolymer, Panthenol, Niacinamide, Arginine, PEG-40 Hydrogenated Castor Oil, Ethylhexylglycerin, Phenoxyethanol, and water is added to the composition until the desired volume is achieved. A method for preparing the composition for hair growth is also provided.

The invention relates to the technical field of biological medicine, and discloses a platelet-rich plasma exosome gel preparation method, which comprises: carrying out exosome separation on a PRP sample by using a high-speed centrifuge; stuffing the exosome precipitate into the shell-sphere structure to prepare core-shell structure particles so as to coat the exosome and form a thermal insulation layer; mixing thrombin and calcium gluconate according to a mass ratio of 10: 1, and adding the mixture into PRP to prepare a gel matrix; adding a photoinitiator, the magnetic coloring particles and the core-shell structure particles into the gel matrix, and uniformly mixing to prepare exosome gel; the invention further discloses application of the composition in repairing diabetic foot wounds. According to the invention, the irreversible influence of temporary environment change on the system can be weakened, meanwhile, the double mechanisms of healing are disclosed, during application, secondary arrangement is carried out by using a magnetic field, the release efficiency of PRP-Exo is improved under the later photo-thermal cooperation effect, and accurate formulation of a long-term treatment strategy is facilitated.

The invention discloses explosion-proof high-temperature-resistant tempered glass and a preparation method thereof, and relates to the field of glass manufacturing. The explosion-proof high-temperature-resistant tempered glass comprises tempered glass, a porous interlayer and a coating, wherein the porous interlayer is obtained by gradually heating a mixed solution obtained by mixing a calcium gluconate solution and tetraethoxysilane according to a mass ratio of 1: (3-5) from room temperature to high temperature and curing; and the coating is obtained by curing slurry at 150-200 DEG C, wherein the slurry is obtained by mixing modified vermiculite containing organic cations and hexafluorosilicate according to the mass ratio of 1: (1-3). According to the invention, a mixed solution composed of calcium gluconate and tetraethoxysilane is gradually heated for toughening treatment to form a more compact silicon dioxide network structure, so that the binding force and high temperature resistance of a porous interlayer and common glass are improved; the hexafluorosilicate can form a compact protective film to delay the transfer of heat to the tempered glass, so that the tempered glass is effectively prevented from being broken due to overheating, and the explosion-proof performance is remarkably improved.

The present application relates to the field of food processing technology, and more particularly to a modified frozen dough with oxidized konjac polysaccharide and a preparation method thereof. The frozen dough comprises the following raw materials in parts by weight: 850-950 parts of flour, 500-600 parts of water, 2.55-9.5 parts of oxidized konjac polysaccharide, 8.5-14.25 parts of calcium gluconate, 0.25-1 part of zinc gluconate, and 8-60 parts of a leavening agent. The leavening agent is yeast or baking powder. In the preparation, the oxidized konjac polysaccharide, calcium gluconate and zinc gluconate are uniformly dispersed in water, and then subjected to high-pressure homogenization and plasma treatment. All the raw materials are put into a dough mixer, mixed at low speed for 1-3 min, and then mixed at high speed for 3-5 min. After mixing, the dough is divided into small doughs, and rolled into small balls. The doughs are wrapped with plastic wrap and quickly frozen. The frozen dough has improved stability, and the deterioration of the specific volume of the food made from the frozen dough is improved.

The invention relates to a bagging-free quality-improving and efficiency-improving pesticide for reducing the insect fruit rate of pomes and a spraying method of the bagging-free quality-improving and efficiency-improving pesticide. The quality-improving and efficiency-improving pesticide comprises the following components: 1-100 g / L of pullulan; 0.5 g / L to 2 g / L of EDTA-2NaCa; the nutrient solution is prepared from 0.3 g / L to 5 g / L of L-calcium aspartate, 1 g / L to 3 g / L of D-calcium gluconate, 2 g / L to 4 g / L of sucrose fatty acid ester, 5 g / L to 15 g / L of tea polyphenol, 2 g / L to 6 g / L of gallic acid, 0.5 mg / L to 1.5 mg / L of brassinolide, 2 g / L to 4 g / L of fumed silica, 0.1 g / L to 0.3 g / L of xanthan gum, 1 g / L to 3 g / L of D-sorbitol, 0.1 g / L to 0.5 g / L of an anti-coagulant and water serving as a solvent. After the pesticide is sprayed, the pest prevention and control effect is equal to that of bagging, the cost is reduced by 68%, sunburn and bitter pox diseases are reduced, the chlorophyll SPAD value is increased by 22%, the photosynthetic rate is increased by 18%, and high yield is promoted.

The invention relates to the technical field of biochemical engineering, in particular to calcium gluconate with a spherocrystal structure as well as a preparation method and application of the calcium gluconate. The calcium gluconate product with the spherocrystal structure can be prepared by adding 1.1 wt%-5 wt% of calcium carbonate ethanol water suspension into 5 wt%-20 wt% of gluconic acid ethanol water solution. Due to the unique spherocrystal structure, the calcium gluconate product has the remarkable advantages that the crystal form is regular, and the core performance of high dissolution rate, high bioavailability and good stability is achieved. The successful construction of the advantageous spherocrystal structure is characterized in that the reaction temperature, the reaction raw material input proportion, the concentration, the solvent system (ethanol-water) and the rotating speed are cooperatively regulated and controlled, and the regulation and control mechanism provides reliable technical support for stable formation of the spherocrystal structure. In addition, the preparation process disclosed by the invention is simple to operate, and has the advantages of environmental protection and no generation of pollutants.

The present invention relates to an ultra-high sulfur capacity two-dimensional carbon nanosheet-based room temperature oxidative desulfurization catalyst, its preparation method, and application. The desulfurization catalyst comprises porous carbon nanosheets and sodium carbonate dispersed on the porous carbon nanosheets. The mass ratio of the porous carbon nanosheets to the sodium carbonate is (60-70):(30-40). The preparation method comprises the following steps: calcining calcium gluconate hydrate in an inert atmosphere, pickling, and washing with water to obtain a two-dimensional porous carbon sheet; mixing the two-dimensional porous carbon sheet with a sodium carbonate solution, stirring, and ultrasonically impregnating to obtain a mixed slurry; rapidly freezing the mixed slurry, and then vacuum freeze-drying to obtain an ultra-high sulfur capacity two-dimensional carbon nanosheet-based room temperature oxidative desulfurization catalyst. The catalyst is used for H2S oxidation reaction. Compared with the prior art, the present invention has the advantages of being able to effectively activate oxygen and significantly improve the sulfur penetration capacity of H2S oxidation at room temperature.

An oral care composition is disclosed comprising tetracalcium phosphate and a water-soluble calcium source; wherein the water-soluble calcium source comprises calcium chloride, calcium nitrate, calcium acetate, calcium lactate, calcium formate, calcium malate, calcium propionate, calcium butyrate, calcium bicarbonate, calcium glycerophosphate, calcium gluconate, calcium ascorbate, calcium glycinate or mixtures thereof; and wherein the composition is an aqueous composition and the water content is at least 5% by weight of the composition.

The invention relates to the technical field of substance detection, and particularly discloses an HPLC-ELCD method for simultaneously detecting calcium gluconate, zinc gluconate and lysine hydrochloride and application. According to the HPLC-ELCD method for simultaneously detecting calcium gluconate, zinc gluconate and lysine hydrochloride, a cation exchange chromatographic column is adopted for isocratic elution of a sample to be detected, and a mobile phase is a methanesulfonic acid-oxalic acid solution; the mobile phase is a methanesulfonic acid-oxalic acid solution, the concentration of methanesulfonic acid is 0.002 mol / L to 0.004 mol / L, and the concentration of oxalic acid is 0.12 g / L to 0.18 g / L. The method disclosed by the invention is high in separation efficiency, good in selectivity, high in detection sensitivity and strong in operability.

The invention provides a method for preparing calcium-based nano particles by a reversed-phase microemulsion method, an organic calcium salt nano material and application of the organic calcium salt nano material as a nano drug, and belongs to the field of biomedical nano materials. The calcium-based nanoparticles can be formed by reacting calcium dodecyl benzene sulfonate with ammonium salt of corresponding ions or a hydroxyl-containing organic matter aqueous solution; the preparation method of the calcium-based nanoparticles has certain universality, and nano-material drugs including calcium succinate, calcium hypophosphite, calcium gluconate, calcium formate, calcium citrate and the like are successfully synthesized. The synthesis method is simple, mild in reaction condition, environment-friendly, high in repeatability, capable of realizing batch preparation and low in raw material cost. When the calcium salt nano-drug such as calcium succinate enters tumor cells through endocytosis, a large number of ions are brought into the cells, and suddenly excessive ions can cause osmotic pressure and homeostasis imbalance in the cells, activate a pyroptosis pathway of the cells and induce death of immunogenic cells.

The invention discloses an anti-inflammatory and detumescence compound traditional Chinese medicine nanogel and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine nanogels. Traditional Chinese medicine effective components with anti-inflammatory and detumescence effects are carried by high-molecular polymers and are dissolved in sodium alginate gel, and respective advantages are fully utilized, so that the anti-inflammatory and detumescence compound traditional Chinese medicine nanogel is prepared. Therefore, safe and effective anti-inflammation and detumescence are achieved, and wound healing is promoted. More specifically, the preparation method comprises the following steps: uniformly mixing effective components which are extracted from traditional Chinese medicines and have anti-inflammatory and detumescence effects with a high-molecular polymer under the ultrasonic action, then adding a sodium alginate solution into the mixture, and dropwise adding a calcium gluconate solution (providing Ca < 2 + >) under a stirring condition; finally, by adjusting ultrasonic time and the proportion of all the components, the optimal experiment condition is determined, and the novel functional compound traditional Chinese medicine nanogel is successfully prepared.

The invention discloses a compound microorganism feed additive for promoting the growth of livestock and poultry. The compound microorganism feed additive comprises microorganism strains, natural plant components and auxiliary materials, the microbial strains comprise 8 to 12 parts of candida utilis, 5 to 9 parts of bacillus licheniformis, 2 to 4 parts of bacillus subtilis, 8 to 12 parts of aspergillus niger, 8 to 12 parts of lactobacillus delbrueckii, 8 to 12 parts of lactobacillus acidophilus, 8 to 12 parts of bifidobacterium and 3 to 7 parts of lactobacillus salivarius; the natural plant components comprise 0.5 to 2 parts of moringa seed powder; the auxiliary materials comprise 20 to 30 parts of cane sugar, 10 to 15 parts of fish meal, 2 to 3 parts of grease, 10 to 20 parts of soybean meal, 5 to 10 parts of pupa powder, 10 to 15 parts of zinc lactate, 1 to 2 parts of calcium gluconate, 3 to 5 parts of calcium carbonate and 2 to 4 parts of paeonol. Microbial strains in the compound microbial feed additive can generate various growth regulatory factors such as vitamins, amino acids and organic acids, so that the growth and development of livestock and poultry are stimulated, and the growth speed is increased.

The invention discloses a composite hydrogel grouting material and a preparation method and application thereof, and belongs to the technical field of hydrogel grouting materials, the composite hydrogel grouting material is a two-component system, and the two-component system comprises a component A and a component B; the component A and the component B are mixed to form an ionic covalent bi-crosslinking system, that is, calcium lactate / calcium gluconate in the component B and sodium alginate in the component A are rapidly subjected to ionic crosslinking, initial setting within 15-38 seconds is achieved, and it is ensured that slurry is rapidly formed after being injected into a flowing water channel and cannot be washed away by water flow; meanwhile, acrylamide and N, N '-methylene bisacrylamide form covalent crosslinking under the action of an initiator-accelerant, so that the structural stability of the gel is improved. The contradiction that the existing single cross-linked hydrogel is fast in gelation and low in strength and high in strength and slow in gelation is broken, and efficient leaking stoppage can be realized in a flowing water environment with the flow velocity of 0.1-1.0 m / s.

The utility model relates to the technical field of medicine production, and discloses a calcium glucarate mixing device with a quantitative blanking function, which comprises a mixing reaction main body mechanism, the mixing reaction main body mechanism comprises a mixing reaction bin body, and the mixing reaction bin body is provided with a stirring and mixing mechanism and a quantitative blanking mechanism in a matching way. According to the quantitative blanking device, the combined quantitative blanking structure design is adopted, the quantitative blanking device comprises the metering pump and the proportional valve for quantitative blanking, the observation hopper is arranged between the proportional valve and the metering pump, and the metering pump can accurately extract and convey a certain amount of materials to the observation hopper according to set parameters, so that the quantitative blanking is realized. Quantitative materials conveyed by the metering pump can be observed through the observation hopper, the quantitative valve can control the flow and the discharging amount of the materials according to the preset opening degree and time, combined quantitative discharging work is carried out through the two-stage quantitative discharging structure, and the matching degree of the discharging amount of the materials and a set value after long-time use is guaranteed.

The invention relates to a washing and drying two-in-one washing agent special for a dish-washing machine, and belongs to the technical field of daily chemicals, and the washing and drying two-in-one washing agent comprises the following components by mass: 4-10% of a low-foaming surfactant; 10-40% of an enzyme-loaded compound; 2-30% of a chelating agent; 5-30% of an alkaline auxiliary agent; 0.1 to 5.0 percent of an auxiliary agent; and the balance of filler. Carboxymethyl cellulose and nano cellulose crystals are used as raw materials to be crosslinked with calcium gluconate to form a crosslinked network, an enzyme-polyethyleneimine compound is loaded in the crosslinked network, and the surface of the formed porous composite aerogel is coated with a hydroxypropyl methyl cellulose membrane, so that the retention rate of enzyme activity is remarkably improved, and the enzyme activity is improved. And reduction of the washing effect caused by rapid enzyme inactivation in the high-temperature washing process of the dish-washing machine is avoided. The low-foam surfactant, the enzyme-loaded compound, the chelating agent and other main components are added in the formula of the detergent, so that the detergent has low-foam, quick-drying and excellent stain removal and scale resistance effects.

The invention provides a method for determining a dissolution curve of a calcium gluconate tablet, which adopts ion chromatography (IC) chromatography for determination and takes an electrical conductivity detector as a detector. A cation exchange column is used as a chromatographic column; and a methanesulfonic acid solution is used as a leacheate. According to the method, quantification can be carried out through calcium detection, the method has the characteristics of high operability and low interference, and support is provided for evaluation and research on the consistency of the calcium gluconate tablets.

The application provides a kind of calcium gluconate co-catalytic production equipment and method, it is related to gluconate production equipment technical field.The device reaction chamber, reaction rotating cylinder, air pump, circulating flow guide pipe, injection pipe, driving device and circulating pump;Reaction rotating cylinder is set in reaction chamber, and reaction rotating cylinder is rotatably connected with driving device;Reaction rotating cylinder is rotatably connected with the top of reaction chamber;The top of reaction chamber is provided with suction port;Air pump is communicated with suction port;Circulating flow guide pipe's flow guide inlet is communicated with reaction chamber;The flow inlet of circulating flow guide pipe is connected with circulating pump;Injection pipe's injection inlet is connected with the flow outlet of circulating pump;Injection pipe's injection outlet corresponds with liquid inlet;Gas inlet is formed in the side wall of reaction chamber.The device can efficiently improve the contact effect of oxygen and solution, and effectively utilize the oxygen generated by reaction to achieve the effect of improving oxygen utilization rate.

The invention discloses a method for detecting oxalate in calcium gluconate and sodium chloride injection, and relates to the technical field of drug analysis and detection. The detection method comprises the following steps: S1, preparing a test solution and a reference solution; s2, adding hydrochloric acid and high-purity zinc into the test solution, standing for 4-6 minutes, adding a phenylhydrazine hydrochloride solution into the test solution, heating until boiling, immediately cooling, and adding hydrochloric acid and a potassium ferricyanide solution to obtain a first mixed solution; adding hydrochloric acid and high-purity zinc into the reference substance solution, standing for 4-6 minutes, adding a phenylhydrazine hydrochloride solution into the reference substance solution, heating until boiling, immediately cooling, and adding a hydrochloric acid solution serving as a potassium ferricyanide solution to obtain a second mixed solution; and judging whether the content of oxalate in the test solution exceeds the standard or not by comparing the color depth of the first mixed solution and the color depth of the second mixed solution. Oxalates in the calcium gluconate and sodium chloride injection can be visually and rapidly detected through colorimetry, specificity and durability are good, and operation is easy and convenient.

To provide a composition for oral cavity containing an enzyme, excellent in stability of the enzyme, and capable of improving harsh taste.SOLUTION: The composition for the oral cavity comprises (A) sodium fluoride, (B) one or more kinds selected from the group consisting of calcium chloride, calcium gluconate, calcium lactate and calcium pantothenate, (C) one or more kinds selected from the group consisting of condensed phosphoric acids and their alkali metal salts and (D) an enzyme.SELECTED DRAWING: None

The utility model relates to the technical field of calcium glucarate production, and discloses a precipitation device convenient for internal cleaning and used for calcium glucarate production, which comprises a tank body, a driving motor, a cross rod, a rubber scraper blade and a vibration motor, a top plate is fixed to the top in the tank body through bolts, a driving motor is installed on the top of the top plate through an installation frame, an output shaft, located in the tank body, of the driving motor is connected with a vertical rod through a connecting sleeve, connecting plates are welded to the two sides of the vertical rod at equal intervals, and side plates are fixed to one ends of the connecting plates through bolts. Rubber scrapers are fixed to the sides, away from the connecting plates, of the side plates through bolts. According to the device, D-gluconate after reaction in the tank body is vibrated through the vibration motor and the spring, the precipitation speed of the D-gluconate is increased, the rubber scraper on one side of the side plate is driven by the driving motor to clean and scrape the inner side of the tank body, the purpose of cleaning the interior of the tank body is achieved, and the device is suitable for being widely popularized and used.

The invention discloses a method for detecting glucuronic acid in a calcium gluconate bulk drug. The method has high system applicability, has incomparable advantages in specificity, quantitation limit, detection limit, linear range, repeatability and durability, and has high precision.

The invention discloses a method for detecting the content of aluminum in a calcium gluconate and sodium chloride injection, which comprises the following steps of: heating and concentrating 200ml of calcium gluconate and sodium chloride injection, and carrying out pre-treatment of ignition ashing or wet digestion or microwave digestion on concentrate; then taking the pretreated sample and a 1% 3-amino-5-hydroxypyrazole derivative agent solution, and carrying out a derivative reaction in an aqueous solution system containing an acetic acid-ammonium acetate buffer solution (pH 4.5) for about 15 minutes; finally, a ZORBAXEclipse Plus (C18) (250 * 4.6 mm, 5 [mu] m) chromatographic column is used, a mixed solution of methanol and a 0.1% formic acid aqueous solution containing 10 mM ammonium acetate (40: 60) is used as a mobile phase, and a high performance chromatography-ultraviolet detection method is carried out under the detection wavelength of 254 nm. The detection method has the advantages of high sensitivity, almost no detection interference, good accuracy, stable formed aluminum derivative, no high-toxicity reagent in the test process, short analysis time and the like, and can effectively overcome the defects in the prior art. The aluminum in the calcium gluconate and sodium chloride injection can be effectively controlled, and the quality of the calcium gluconate and sodium chloride injection is well ensured.