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A kind of manufacturing method of degradable tube and degradable bracket

A manufacturing method and pipe technology, which are applied to stents, devices of human tubular structures, blood vessels, etc., can solve the problems of decreased preparation efficiency and performance of degradable stents, unable to meet the length and radial strength at the same time, and improve the preparation efficiency and performance, the effect of meeting the strength

Active Publication Date: 2018-11-13
SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to provide a method for manufacturing a degradable tube and a degradable stent, so as to solve the problem that the degradable tube manufactured by the degradable tube manufacturing method in the prior art cannot meet the requirements of length and radial strength at the same time , leading to the problem of decreased production efficiency and performance of degradable scaffolds

Method used

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  • A kind of manufacturing method of degradable tube and degradable bracket
  • A kind of manufacturing method of degradable tube and degradable bracket
  • A kind of manufacturing method of degradable tube and degradable bracket

Examples

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Embodiment 1

[0049] The original biodegradable tube 2 selected in this embodiment is the original polylactic acid degradable tube, and the outer diameter of the original polylactic acid degradable tube obtained by melting and extruding polylactic acid particles is 1.3 mm. The inner diameter is 0.38mm. Place the original polylactic acid degradable tube in the mold 1 with an inner diameter of 3mm, please structure Figure 2a-2c As shown, the length of the mold 1 here is preferably 150 mm. The mold 1 is divided into two cooling sections 11 and a heating section 10 arranged between the two cooling sections 11, maintaining the temperature of the cooling section 11 of the mold 1 down to below the glass transition temperature of the original polylactic acid degradable tube, Usually 25 ~ 40 ℃. One end of the original polylactic acid degradable tube is closed, and the other end is connected to a high-pressure gas circuit.

[0050] The specific process of preparing the deformed polylactic acid or...

Embodiment 2

[0057] In this embodiment, the selected biodegradable tube 2 is a polylactide-caprolactone original degradable tube in which polylactic acid and polycaprolactone are copolymerized at a ratio of 90:10 to prepare polylactide-caprolactone For the steps of the degradable tube, please refer to the steps in Example 1, but the parameters involved in the steps are different. The outer diameter of the prepared original polylactide-caprolactone degradable tube is 1.75mm, and the inner diameter is 0.6mm. The inner diameter of mold 1 is 4.3mm. The mold 1 is heated to 65° C., and both ends of the original polylactide-caprolactone degradable tube are stretched in the axial direction, and the translation speed of the original polylactide-caprolactone degradable tube is 0.5 mm / s. The amount of translation is 120mm. Wherein, after the original polylactide-caprolactone degradable tube is inflated, the mold 1 is heated to 100° C. for 60 seconds to be shaped. The total length of the prepared po...

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Abstract

The invention provides a manufacture method for a degradable tube and a degradable stent. The method comprises the steps that an original degradable tube disposed in a die is heated to a deformation temperature, and an expansion pressure is applied into the original degradable tube, so that the original degradable tube can expand radially and can then be pressed against the inner surface of the die; and after that, the original degradable tube is moved horizontally along the axial direction of the die. The steps are repeated for once or multiple times according to demands. Through horizontal moving of the original degradable tube, predetermined parts can expand radially, so that the degradable tube with a sufficient length can be obtained; and intensity demands for the degradable tube are met during radial expansion of the original degradable tube, so that the prepared degradable tube can satisfy a length requirement and the intensity demands, and efficiency and performance of preparation of the degradable stent are enhanced.

Description

technical field [0001] The invention relates to the technical field of medical device manufacturing, in particular to a method for manufacturing a degradable tube and a degradable bracket. Background technique [0002] Biodegradable stents are made of degradable polymer materials or metal materials, and can support blood vessels in a short period of time after being implanted in the lesion to achieve blood vessel reconstruction. At present, biodegradable stents have been used in the treatment of vascular stenosis. When treating vascular stenosis, the biodegradable stent needs to have sufficient radial strength to support the vessel wall, and the stent needs to maintain sufficient length to support the stenosis. Especially for long vascular lesions, such as peripheral vascular stenosis. After the treatment is completed, the biodegradable stent will degrade in the human environment into organic substances that can be absorbed and metabolized by the human body. [0003] The d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/07A61F2/82
Inventor 陈树国王雪琴孟娟赵敏罗七一
Owner SHANGHAI MICROPORT MEDICAL (GROUP) CO LTD