The invention relates to a high frequency Coriolis mass flowmeter digital signal processing system. The high frequency Coriolis mass flowmeter digital signal processing system comprises a DSP chip, a first signal conditioning module, a second signal conditioning module, a constant flow source, a Pt100 platinum resistor, a first ADC, a second ADC, a third ADC, an analog driver module, an external expansion FLASH module, a PWM output module, a current output module, an external expansion UART module, an HART modulation module, a man-machine interface module, a power down protection module and software. For signal processing of a high frequency Coriolis mass flow sensor, a TMS320C6726 chip with the strong operational capability and the high processing speed is used as a core processor, and the high frequency Coriolis mass flowmeter digital signal processing system is invented. Based on the zero-cross detection algorithm and DTFT algorithm, the high frequency Coriolis mass flowmeter digital signal processing system solves the problem that the algorithm cannot guarantee real-time performance after sampling frequency of high frequency sensor signals is increased.