CRISPR-Cas systems and methods for altering expression of gene products

A gene product, genome technology, applied in the field of CRISPR-CAS systems and methods for altering the expression of gene products
CN106480080AActive Publication Date: 2017-03-08THE BROAD INST INC +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE BROAD INST INC
Publication Date
2017-03-08

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Abstract

The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system.
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Description

[0001] This application is a divisional application of the national application number 201380072715.1 (PCT / US2013 / 074743) filed on December 12, 2013 entitled "CRISPR-CAS system and method for altering the expression of gene products" .

[0002] Related applications and cited references

[0003] This application claims the title "CRISPR-Cas System and Method for Altering the Expression of a Gene Product (CRISPR-Cas. CAS SYSTEMSAND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS)" US provisional patent application 61 / 842,322 and US patent application 14 / 054,414 priority. Filed on December 12, 2012, January 2, 2013, March 15, 2013, and June 17, 2013, respectively, with Bode Reference No. BI-2011 / 008 / WSGR Docket No. 44063- 701.101, BI-2011 / 008 / WSGR Docket No. 44063-701.102, Broad Reference No. BI-2011 / 008 / VP Docket No. 44790.02.2003, and BI-2011 / 008 / VP Docket No. 44790.03.2003, all titled "Use Priority claims to U.S. Provisional Patent Applications 61 / 736,527, 61 / 748,427, 61 / 791...

Claims

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