Implantable closed-loop deep brain stimulation system

A deep-brain, implantable technology, applied in the field of implantable closed-loop deep brain stimulation system, can solve problems such as high system complexity, little significance for symptom improvement, and difficult implementation of implantable medical devices, etc., to achieve Effect of reducing side effects and saving battery power

Active Publication Date: 2019-01-04
TSINGHUA UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this approach doesn't do much to improve the patient's symptoms that persist while awake
In addition, an integrated closed-loop deep brain stimulator based on sleep detection needs to integrate an additional body motion sensor to collect feedback signals, which is difficult to fully realize in the body of implantable medical devices
There is also a sleep quality assessment system that needs to use EEG signals (EEG signals do not belong to deep brain electrical signals) or an external polysomnography system to complete the judgment of sleep stages and quality, and the complexity of the system is relatively high.

Method used

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  • Implantable closed-loop deep brain stimulation system
  • Implantable closed-loop deep brain stimulation system
  • Implantable closed-loop deep brain stimulation system

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Embodiment Construction

[0057] Embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the drawings, wherein the same or similar reference numerals represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary only for explaining the present invention and should not be construed as limiting the present invention.

[0058] see figure 1 The closed-loop deep brain stimulator system 100 provided by the first embodiment of the present invention includes a stimulating electrode 1, a pulse generator 2, a signal acquisition module 3, a sleep analysis module 4, a closed-loop control module 5, a signal transmission module 6, a metal casing 7 and In vitro monitoring system8. The stimulating electrode 1, the pulse generator 2, the signal acquisition module 3, the sleep analysis module 4, the closed-loop control module 5, the signal transmission ...

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Abstract

The invention provides a fully implanted closed-loop brain deep simulating system based on brain deep electric signal sleep detection. The system utilizes a brain deep electric stimulator electrode for sensing an electrocardiosignal and a brain deep electric signal at a stimulating target point. The system extracts time domain, frequency domain and complexity analysis characteristics and further realizes detection and judgment on a sleep state by means of a classification algorithm, thereby adjusting the switching state and the output parameter of the stimulator and realizing closed-loop nerve stimulation in the sleep state. The implanted closed-loop brain deep simulating system provided by the invention has advantages of reducing side effects of brain deep electric stimulation and saving electric energy of a battery.

Description

technical field [0001] The invention relates to an implantable medical device, in particular to an implanted closed-loop deep brain stimulation system. Background technique [0002] A deep brain stimulator is an implantable medical device that is mainly used to treat movement disorders and mental disorders. Its indications include Parkinson's disease, dystonia, essential tremor, and obsessive-compulsive disorder. A deep brain stimulator generally includes a pulse generator, extension wires, and stimulating electrodes. [0003] The deep brain stimulator procedure has opened a window into the mysteries of these diseases and the brain. Through clinical records, it is found that patients with Parkinson's disease, dystonia, essential tremor and obsessive-compulsive disorder have significant differences in their corresponding stimulation targets (such as subthalamic nucleus, globus pallidus, ventral intermediate nucleus of thalamus, etc.) neuron firing characteristics. This dis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N1/36A61B5/0402A61B5/0476
CPCA61B5/4809A61N1/36067A61B5/318A61B5/369
Inventor 陈玥郝红伟李路明
Owner TSINGHUA UNIV
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