Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composite skin wound disinfectant and preparation method thereof

A technology for skin wounds and disinfectants, applied in skin diseases, anti-inflammatory agents, antifungal agents, etc., can solve the problems of poor consumer experience and single function, and achieve the effect of stable properties and fast action speed

Inactive Publication Date: 2017-04-26
QINGDAO CHENLAND MARINE BIOTECH CO LTD
View PDF12 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to develop a composite skin wound disinfectant, which can stop bleeding, relieve pain, and promote wound healing and regeneration while performing efficient sterilization. It is non-irritating to the wound and has high safety performance. The problem of single function and poor consumer experience, the specific content of the invention is as follows

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composite skin wound disinfectant and preparation method thereof
  • Composite skin wound disinfectant and preparation method thereof
  • Composite skin wound disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The recipe is made according to the following proportions:

[0028] Polyhexamethyleneguanidine hydrochloride: 0.1%

[0029] Benzalkonium chloride: 0.1%

[0030] Chitosan quaternary ammonium salt: 0.1%

[0031] Lysozyme: 0.01%

[0032] Agrimony extract: 0.01%

[0033] White and extract: 0.01%

[0034] Catechin Extract: 0.01%

[0035] Purple Pearl Extract: 0.01%

[0036] Collagen peptide: 0.01%

[0037] Allantoin: 0.1%

[0038] Preparation method:

[0039] 1) Weigh all the raw materials required for the disinfectant in proportion, first dissolve polyhexamethyleneguanidine hydrochloride and benzalkonium chloride with an appropriate amount of water, stir to dissolve, and dissolve at a temperature of 50°C, then add biological antibacterial enhancers ( Chitosan quaternary ammonium salt, lysozyme), continue stirring until a clear homogeneous solution;

[0040] 2) Weigh Agrimony, Baiji, Catechin, Auranthus macrophylla, collagen polypeptide, and allantoin in proportion...

Embodiment 2

[0044] The recipe is made according to the following proportions:

[0045] Polyhexamethyleneguanidine hydrochloride: 0.5%

[0046] Benzalkonium chloride: 0.2%

[0047] Chitosan Lactate: 1%

[0048] Lysozyme: 1%

[0049] Agrimony Extract: 2%

[0050] White and extract: 2%

[0051] Catechin Extract: 2%

[0052] Purple Pearl Extract: 2%

[0053] Sea cucumber peptide: 1%

[0054] Allantoin: 0.5%

[0055] Preparation method:

[0056] 1) Weigh all the raw materials required for the disinfectant in proportion, first dissolve polyhexamethyleneguanidine hydrochloride and benzalkonium chloride with an appropriate amount of water, stir to dissolve, and dissolve at a temperature of 60°C, then add biological antibacterial enhancers ( chitosan lactate, lysozyme), continue stirring until a clear homogeneous solution;

[0057] 2) Weigh Agrimony, Baiji, Catechin, Purple Pearl, Sea Cucumber Peptide, Allantoin in proportion, stir and dissolve with an appropriate amount of water, the di...

Embodiment 3

[0061] Embodiment 1 collation of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, Pseudomonas aeruginosa killing test result:

[0062] Table 1: Killing effect on Escherichia coli

[0063]

[0064] Table 2: Killing effect on Staphylococcus aureus

[0065]

[0066] Table 3: Killing effect on Pseudomonas aeruginosa

[0067]

[0068] Table 4: Killing effect on Candida albicans

[0069]

[0070] Note: Negative controls all grew sterile.

[0071] Embodiment 1 is to the field test of skin disinfection

[0072] experimental method:

[0073] 1. Inspection basis: 2.1.2.8 of the Ministry of Health's "Disinfection Technical Specifications" (2002 edition).

[0074] 2. Experimental concentrations of disinfectants: polyhexamethyleneguanidine hydrochloride (0.2%), benzalkonium chloride (0.05%).

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Molecular weightaaaaaaaaaa
Login to View More

Abstract

The invention relates to a skin wound disinfectant which can be used for antibacterial disinfection of various acute and chronic wounds and promotion of the repair and regeneration of damaged tissues. The skin wound disinfectant includes the main components of polyhexamethylen guanidine hydrochloride, benzalkonium chloride, biological antibacterial enhancers (lysozyme, chitosan and a derivative thereof, allantoin and the like), and functional components (hemostatic and analgesic natural plant extraction components hairyvein agrimony, Rhizoma Bletillae, catechu, Callicarpa macrophylla, marine polypeptide extract and the like). The disinfectant has good antibacterial disinfection and hemostatic and analgesic effect, is mild and non-irritation to the skin wounds, promotes quick healing of the wounds, and is safe and environment-friendly. The raw materials of the disinfectant are easy to obtain, the preparation process is simple, the production cost is low, and the cost performance ratio is high.

Description

technical field [0001] The invention relates to the field of disinfectants, and is especially suitable for disinfection of skin wounds. Background technique [0002] Traditional skin disinfectants, according to their composition, are mostly chemical disinfectants, such as quaternary ammonium salts (represented by benzalkonium chloride and benzalkonium bromide), guanidine disinfectants (chlorhexidine, polyhexamethyleneguanidine Representative) and hydrogen peroxide, iodophor, triclosan (triclosan), etc. Some chemical disinfectants have potential safety hazards, but disinfectants prepared from pure biological ingredients cannot guarantee the high efficiency of sterilization. Therefore, the current compound disinfectant of chemical disinfectant and biological antibacterial component is a trend in the field of disinfectant in the future. On the one hand, it ensures the high efficiency of disinfectant sterilization, on the other hand, it reduces the amount of chemical disinfectan...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K38/47A61P31/04A61P31/10A61P7/04A61P29/00A61P17/02A61K38/02A61K38/39A61K31/785A61K31/14A61K31/722A61K36/898A61K31/4166
Inventor 杨毅董刚李乘风
Owner QINGDAO CHENLAND MARINE BIOTECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com