ECM1 protein antibody and applications thereof, and kit
A kit and protein technology, applied in the field of biomedicine, can solve the problems of patient infection, patient psychological burden, physiology, pain, etc., and achieve the effect of reliable data, reliable and accurate detection results, high specificity and sensitivity
Inactive Publication Date: 2017-04-26
CHENGDU PUHUA TECH CO LTD
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Problems solved by technology
[0004] At present, the detection of obstructive and non-obstructive azoospermia is mostly performed by testicular puncture; this method is traditional and will bring psychological burden and physical pain to patients, as well as the risk of infection to patients
Method used
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Embodiment 1
[0045] This embodiment provides an ECM1 protein antibody, which can specifically recognize the ECM1 protein, and uses the ECM1 protein as the recognition target of the ECM1 protein antibody. The amino acid sequence of the ECM1 protein is shown in SEQ ID No.1.
Embodiment 2
[0047] This embodiment provides an ECM1 protein detection kit, the ECM1 protein detection kit includes an ECM1 protein antibody, and the amino acid sequence of the ECM1 protein is shown in SEQ ID No.1. The ECM1 protein antibody can react with the ECM1 protein and specifically recognize the ECM1 protein.
Embodiment 3
[0049] This embodiment provides an ECM1 protein detection kit, the ECM1 protein detection kit includes an ECM1 protein antibody, and the amino acid sequence of the ECM1 protein is shown in SEQ ID No.1. The ECM1 protein antibody can react with the ECM1 protein and specifically recognize the ECM1 protein.
[0050] ECM1 protein detection kit also includes ECM1 standard protein.
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Abstract
The invention relates to an ECM1 protein antibody and applications thereof, and a kit, and belongs to the technical field of biomedicine. According to the present invention, the ECM1 protein antibody can specifically bind to ECM1 protein, and has high specificity and high sensitivity; with the application of the ECM1 protein antibody in ECM1 protein detection, the ECM1 protein can be detected specifically and sensitively so as to obtain the reliable and accurate detection result; with the application of the ECM1 protein antibody to prepare the ECM1 protein detection kit, the ECM1 protein can be rapidly and conveniently detected, the ECM1 protein can be quantitatively detected, and the reliable and accurate data can be provided for the follow-up detection and analysis; and with the application of the ECM1 protein antibody to detect the ECM1 protein in the semen, the detection result can be accurately and rapidly obtained.
Description
technical field [0001] The present invention relates to the technical field of biomedicine, and in particular to an ECM1 protein antibody and its application and kit. Background technique [0002] Extracellular matrix protein 1 (ECM1) is a secretory glycoprotein isolated from mouse osteoblast stromal cells in 1994. Extracellular matrix protein 1 is widely present in various tissues and organs, and is associated with many diseases. [0003] Studies in recent years have found that ECM1 has multiple functions. For example, the deletion of ECM1 gene can lead to the occurrence of lipoproteinosis. There are high titers of ECM1 autoantibodies in the serum of patients with lichen sclerosus, and some patients with chronic lichen sclerosus It is prone to be complicated by malignant tumors, mainly squamous cell carcinoma. It is known that the extracellular matrix plays a major role in the occurrence and metastasis of tumors. [0004] At present, the detection of obstructive and non-...
Claims
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IPC IPC(8): G01N33/68G01N21/31C07K16/18
CPCC07K16/18G01N21/31G01N33/68G01N33/6893
Inventor 刘畅王小容许文明
Owner CHENGDU PUHUA TECH CO LTD