System for calculating fractional flow reserve and method for setting boundary conditions

Abstract

The invention provides a system for calculating blood flow reserve fraction and a method for setting boundary conditions. The system includes: a vascular tree model generation module, which acquires medical images, executes segmentation and reconstructs the geometric model of the individual vascular tree; a calculation grid generation module, generates a calculation grid for the geometric model, and establishes a CFD model of the vascular tree; a boundary condition setting module , to set the corresponding inlet and outlet boundary conditions for the CFD model of the vascular tree; the attribute setting module, to set the physical properties of the blood and the flow equation; the solver, based on the inlet and outlet boundary conditions, the set physical properties and the flow equation, the blood vessel The CFD model of the tree is solved to obtain the fluid parameters throughout the vascular tree; and the post-processing module is used to post-process the fluid parameters to obtain the blood flow reserve fraction, and the inlet and outlet boundary conditions are individual-specific. The system and method achieve a clinically acceptable calculation time while ensuring the accuracy of the simulation results.

Description

technical field [0001] The present invention relates to systems and methods for computational analysis of human physiology and hemodynamics, and more particularly to a system for simulating and calculating fractional blood flow reserve using computational fluid dynamics (CFD), and computational fluid dynamics (CFD) for vascular trees. CFD) model to set the corresponding inlet boundary conditions and outlet boundary conditions. Background technique [0002] The main cause of coronary heart disease is coronary stenosis caused by arteriosclerosis. Coronary stenosis can cause significant changes in coronary blood flow and other hemodynamics, resulting in relative and absolute myocardial ischemia. Coronary angiography and intravascular ultrasonography are both considered to be the "gold standard" for the diagnosis of coronary heart disease, but they can only evaluate the degree of stenosis by imaging, and how much the stenosis affects the distal blood flow (functional evaluation...

AI Technical Summary

Problems solved by technology

The boundary conditions set based on this assumption or statistics cannot reflect the specificity of individuals, which affects the accuracy of simulation calculations

In addition, in order to automatically and accurately predict the fluid parameters of clinically concerned vascular branches, existing vascular computing systems usually need to perform CFD modeling and calculation of the relevant entire vascular tree (such as the entire vascular tree of the coronary artery), which takes a long time. , and consumes a lot of computing resources, which hinders its clinical promotion

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