Mixed probiotic tablets and low-temperature coating preparation method thereof

A technology of probiotic tablets and inoculants, applied in the directions of bacteria, lactobacilli, bifidobacteria, etc. used in food preparation, can solve the problems of easy loss of probiotic activity, improve the digestion and absorption rate of the body, and improve the structure. ability, prevention of tumor growth and efficacy in type 2 diabetes

Inactive Publication Date: 2017-05-24
BEIJING SCITOP BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The technical problem solved by the present invention is to overcome the defect that the probiotic body activity of the mixed probiotic tablet in the above-mentioned prior art is susceptible to loss during the preparation process and during the shelf life of the product, and at the same time increase the added value of the mixed probiotic tablet, im...

Method used

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  • Mixed probiotic tablets and low-temperature coating preparation method thereof
  • Mixed probiotic tablets and low-temperature coating preparation method thereof
  • Mixed probiotic tablets and low-temperature coating preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: the fermentation preparation method of Sizhong microbial agent

[0041] The fermentation preparation of Lactobacillus acidophilus KT-A1 inoculum, Lactobacillus casei inoculum, Bifidobacterium animalis subsp. V9 inoculum and Lactobacillus plantarum P-8 inoculum comprises the following steps:

[0042] Take a ring of activated Lactobacillus acidophilus KT-A1, Lactobacillus casei Zhang, Bifidobacterium animalis subsp. V9 and Lactobacillus plantarum P-8 respectively, and inoculate them into MRS medium respectively. Cultivate for 18 hours at the same temperature at 37°C and at the same rotating speed of 100rpm to obtain the primary seed solution; transfer the cultivated primary seed solution to the MRS medium again according to the inoculum size of 3% (v / v) for secondary activation. After the activation time of 18h, the secondary seed liquid was obtained; the secondary seed liquid was respectively inserted into the 5L fermenter of the 3L fermenter culture medium...

Embodiment 2

[0049] Embodiment 2: the preparation of mixed probiotic tablet

[0050] A mixed probiotic tablet, mainly prepared from the following raw materials in parts by weight: 2 parts of Lactobacillus acidophilus KT-A1 bacterial agent, 2 parts of Lactobacillus casei bacterial agent, 2 parts of Bifidobacterium animalis subsp. plantarum P-8 microbial agent 2 parts, galacto-oligosaccharide 10 parts, glucose 10 parts, microcrystalline cellulose 10 parts, soluble soybean polysaccharide 0.1 part.

[0051] Another object of the present invention is to provide the preparation method of the low-temperature coating technology of the above-mentioned mixed probiotic tablet, comprising the following steps:

[0052] Raw material mixing: Lactobacillus acidophilus KT-A1 bacterial agent, Lactobacillus casei bacterial agent, Bifidobacterium animalis subsp. The cellulose is compounded and mixed according to the proportion, and the three-dimensional multi-directional motion mixer is used to fully mix und...

Embodiment 3

[0056] Embodiment 3; Preparation of mixed probiotic tablet

[0057] A mixed probiotic tablet, mainly prepared from the following raw materials in parts by weight: 7 parts of Lactobacillus acidophilus KT-A1 bacterial agent, 7 parts of Lactobacillus casei bacterial agent, 7 parts of Bifidobacterium animalis subsp. plantarum P-8 bacterial agent 7 parts, galacto-oligosaccharide 40 parts, glucose 30 parts, microcrystalline cellulose 30 parts, 0.7 part of soluble soybean polysaccharide.

[0058] Another object of the present invention is to provide the preparation method of the low-temperature coating technology of the above-mentioned mixed probiotic tablet, comprising the following steps:

[0059] Raw material mixing: Lactobacillus acidophilus KT-A1 bacterial agent, Lactobacillus casei bacterial agent, Bifidobacterium animalis subsp. The cellulose is compounded and mixed according to the proportion, and the probiotic mixture is obtained by using a three-dimensional multi-direction...

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Abstract

The invention discloses mixed probiotic tablets and a low-temperature coating preparation method thereof and belongs to the field of probiotic tablets. The mixed probiotic tablets are prepared from 2-7 parts of a lactobacillus acidophilus KT-A1 agent, 2-7 parts of a lactobacillus casei Zhang agent, 2-7 parts of a bifidobacterium animalis subsp. lactis V9 agent and 2-7 parts of a lactobacillus plantarum P-8 agent with a low-temperature coating technology. According to the probiotic tablets prepared with the method, bacterium loss of probiotics in a tablet preparation process is avoided, after the tablets are stored for 5 months at the temperature of 37 DEG C, the total viable count of probiotics in the product keeps not lower than 5*10<9> CFU/g; furthermore, storage stability of the probiotics in the shelf life of the product is greatly improved, weight of each tablet is 0.7-0.9 g, the hardness reaches 7 N/cm<2> or higher, the surface is smooth, and the phenomenon of powder falling is avoided. Besides, the mixed probiotic tablets have excellent resistance to gastrointestinal digestive juice, improve capacity of intestinal microbial community structure of a human body and have a regulating function for body immunity.

Description

technical field [0001] The invention belongs to the field of probiotic tablets, in particular to a mixed probiotic tablet and a preparation method for low-temperature coating thereof. Background technique [0002] Probiotics are defined as "live microorganisms that, when ingested in sufficient quantities, provide a beneficial effect on the host". Probiotics have a variety of physiological functions, including improving human intestinal function, inhibiting the growth of harmful bacteria, reducing intestinal diseases, alleviating lactose intolerance, promoting the absorption of sugar, protein, calcium, magnesium and other nutrients, lowering cholesterol, and regulating immunity system, anti-tumor, cancer prevention, etc. However, in order to obtain probiotic effects, it is required that probiotics remain active and metabolically stable in both the product and the host, and reach a certain amount (usually considered to be no less than 10 per gram or milliliter of product). 7...

Claims

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Application Information

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IPC IPC(8): A23L33/135A23P10/28A23P20/10
CPCA23V2002/00A23V2400/125A23V2400/515A23V2400/113A23V2400/169A23V2200/3204A23V2200/32A23V2200/324A23V2200/3262A23V2200/328A23V2200/308A23V2200/30A23V2250/28A23V2250/51A23V2250/51084A23V2250/61
Inventor 高鹏飞杨慧娟
Owner BEIJING SCITOP BIO TECH CO LTD
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