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Application of bacillus coagulans in preparation of preparations for preventing or treating Parkinson's disease

A technology for Bacillus coagulans and Parkinson's disease, which is applied in the field of Bacillus coagulans in the preparation of preparations for preventing or treating Parkinson's disease, and can solve the problems of limited use, different sources of medicinal materials, and difficult to control symptoms.

Inactive Publication Date: 2017-06-13
QINGDAO EASTSEA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

With the prolongation of the time of patients receiving western medicine therapy, their symptoms are gradually difficult to control, and even aggravate the condition
The disadvantages of traditional Chinese medicine are that it is based on experience, there is no fixed prescription and dosage, and there are large differences between patients, doctors have uneven clinical experience, different sources of medicinal materials, and limited use, so it is difficult to produce good clinical effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0033] Preparation Example 1 The preparation of bacillus coagulans powder

[0034] 1 Preparation of bacteria powder and identification of strains

[0035] Take samples of human feces, soil, haystack substrate, etc., and then put the samples in a sterilized bottle, take 2 grams of the sample and add it to 18mL of sterilized diluent, mix well, and carry out 10 -1 、10 -2 、10 -3 、10 -4 , 10 -5 , 10 -6 , 10 -7 Gradient dilution, take 10 -5 , 10 -6 , 10 -7Three dilution gradients, spread on the solid medium for selective single colony isolation of Bacillus coagulans, place in an incubator, culture at 37°C for 48 hours, select a single colony with good growth and inoculate it into the liquid expansion medium of Bacillus coagulans , expanded at 37°C for 48 hours. After the obtained culture solution is centrifuged (12000rpm) to separate the thalline, the thalline is freeze-dried in vacuum to prepare dry bacterial powder, and the number of viable bacteria is 1×10 9 CFU / g or ...

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PUM

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Abstract

The invention discloses application of bacillus coagulans in preparation of preparations for preventing or treating Parkinson's disease. The application specifically comprises the steps of preventing or treating the Parkinson's disease and reducing symptoms of the Parkinson's disease by using bacillus coagulans.

Description

technical field [0001] The invention relates to the application of bacillus coagulans in preparing preparations for preventing or treating Parkinson's disease, in particular to using bacillus coagulans to prevent or treat Parkinson's disease and reduce the symptoms of Parkinson's disease. Background technique [0002] Parkinson's disease (PD), or paralysis agitans, is a common degenerative disease of the central nervous system among middle-aged and elderly people, and it is also the second most common neurodegenerative disease after Alzheimer's disease. Parkinson's disease is clinically characterized by resting tremor, muscle rigidity, bradykinesia, and abnormal posture and gait, often accompanied by autonomic nervous system involvement and cognitive decline. The disease has a slow onset and gradual development, and the initial symptoms are often not noticed by people. In the later stage, severe muscle rigidity accompanied by general stiffness often occurs, and eventually le...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/742A61K35/745A61P25/16A23L33/135
CPCA23V2002/00A61K35/742A61K35/745A61K2300/00A23V2200/322
Inventor 崔云龙赵婀姿李洪福
Owner QINGDAO EASTSEA PHARMA