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Composition for improving or treating acute radioactive oropharyngeal mucositis and preparation method and application thereof

A radioactive and mucositis technology, applied in the field of traditional Chinese medicine, can solve the problems of incomplete extraction of active ingredients, time-consuming and laborious, inconvenient administration, etc.

Active Publication Date: 2017-08-04
四川仙鹤生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In recent years, traditional Chinese medicine has been more and more accepted by everyone for its advantages of treating both symptoms and root causes and having less toxic and side effects. However, most of the current methods of taking traditional Chinese medicine are made into decoctions for decoction. This method requires long-term decoction, which is time-consuming and laborious. It is inconvenient to take, and the taste is not good; and the active ingredients in the traditional Chinese medicine cannot be completely extracted by decoction, resulting in the waste of traditional Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Embodiment 1: weigh 150g of fresh reed root, 100g of honeysuckle, 150g of Luo Han Guo, 100g of peppermint, 20g of gallinaceous gold, 50g of fungus, the raw materials are selected without mold and insects, and the fungus is boiled and then dried and pulverized into fine powder. Grind gallinacea into the finest powder, add 6 times the amount of water to the remaining raw materials and decoct for 1.5 hours, filter, add 5 times the amount of water to the filter residue, cook for 1.2 hours, filter, add 5 times the amount of water to decoct for 1 hour, filter; The filtrates are combined, concentrated, spray-dried, and then added with the finest powder of gallinaceous gold, fine powder of Auricularia auricula and maltodextrin to prepare, mixed evenly, granulated and dried to obtain the product.

[0106] How to use: Brew and drink, take it three times a day in the morning, afternoon and evening. The daily dose is based on crude drug 57g.

[0107] Clinical research on the impro...

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PUM

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Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a composition for improving or treating acute radioactive oropharyngeal mucositis and a preparation method and application thereof. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of improving or treating discomfortable symptoms of acute stage reaction of the oropharyngeal mucositis such as dryness and pain of oropharynx, red and swelling, erosion, ulcer and the like caused by radiation chemotherapy. The composition for improving or treating the acute radioactive oropharyngeal mucositis is characterized by being prepared from the following crude drugs by weight proportion: 12-18 parts of rhizoma phragmitis, 8-12 parts of flos lonicerae, 12 to 18 parts of fructus momordicae, 7 to 12 parts of herba menthae, 1 to 3 parts of endothelium corneum gigeriae galli, and 3 to 8 parts of auricularia polytricha or white fungus. The composition for improving or treating the acute radioactive oropharyngeal mucositis has the effects of nourishing Yin and generating body fluid, diminishing inflammation, reducing phlegm, increasing appetite, greatly improving the discomfortable symptoms of the acute stage reaction of the oropharyngeal mucositis such as the dryness and pain of oropharynx, the red and swelling and the like, and being suitable for patients with head and neck cancer in the period of radiotherapy and chemotherapy to drink. In particular, the composition for improving or treating the acute radioactive oropharyngeal mucositis is prepared as a solid beverage of the traditional Chinese medicine, and has the advantages of being convenient to brew, good in taste and simple in production process.

Description

technical field [0001] The present invention relates to a composition for improving or treating acute radiation-induced oropharyngeal mucositis, its preparation method and use, which can improve or treat the acute phase of oropharyngeal mucositis caused by acute radiation chemotherapy, such as dry pain, swelling, erosion, and ulcers. The effect of reflecting discomfort symptoms belongs to the field of traditional Chinese medicine. Background technique [0002] With the gradual increase in the occurrence and detection rate of malignant tumors, the promotion of radiotherapy and the popularity of intracavitary irradiation, in order to improve the long-term survival rate of patients with malignant tumors, radiotherapy has gradually become an important method for the treatment of malignant tumors combined with chemotherapy. At the same time, after many malignant tumors of the head and neck receive radiation therapy, the incidence of the accompanying complication "radiation oropha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P1/02A61K35/57
CPCA61K9/0095A61K9/1652A61K35/57A61K36/07A61K36/355A61K36/42A61K36/534A61K36/899A61K2236/331A61K2236/51A61K2300/00
Inventor 罗霞张智敏余梦瑶谢刚许晓燕龙鑫李芳滕昊岐江南章淼魏巍贺黎铭
Owner 四川仙鹤生物技术有限公司
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