Composition for improving or treating radiation oropharyngeal mucositis, preparation method and application

Abstract

The invention belongs to the field of traditional Chinese medicines, and relates to a composition for improving or treating radioactive oropharyngeal mucositis and a preparation method and application thereof. The composition for improving or treating the radioactive oropharyngeal mucositis has the effects of improving or treating discomfortable symptoms of later period oropharyngeal mucositis such as dryness of oropharynx, hypogeusia, sticky pharyngeal sputum which is different to expectorate and the like caused by radioactive chemotherapy. The composition for improving or treating the radioactive oropharyngeal mucositis is characterized by being prepared from the following crude drugs in parts by weight: 12 to 18 parts of fructus hippophae, 8 to 12 parts of fructus mume, 18 to 24 parts of fructus mori, 12 to 18 parts of rhizoma polygonati odorati, 8 to 12 parts of fructus canarii, and 3 to 8 parts of auricularia polytricha or white fungus. The composition for improving or treating the radioactive oropharyngeal mucositis has the effects of nourishing Yin and generating body fluid, reducing phlegm, increasing appetite, greatly improving the discomfortable symptoms of the later period of the oropharyngeal mucositis such as the dryness of oropharynx, the hypogeusia, the sticky pharyngeal sputum which is different to expectorate and the like, and being suitable for patients with head and neck cancer in the late period of radiotherapy and chemotherapy to drink. In particular, the composition for improving or treating the radioactive oropharyngeal mucositis is prepared as a solid beverage of the traditional Chinese medicine, and has the advantages of being convenient to brew, good in taste and simple in production process.

Description

technical field [0001] The invention relates to a composition for improving or treating radiation-induced oropharyngeal mucositis, a preparation method and application thereof, which can improve or treat radiation-induced oropharyngeal mucous membranes such as dryness of the oropharynx, loss of taste, sticky phlegm in the pharynx, and difficulty in coughing up caused by radiation chemotherapy. The efficacy of the discomfort symptoms in the late stage of inflammation belongs to the field of traditional Chinese medicine. Background technique [0002] Radiotherapy is the first choice for the treatment of many head and neck malignancies, and the treatment effect is good. However, when radiation is used to treat tumors, it is easy to cause damage to its adjacent tissues and organs, resulting in a series of adverse reactions, among which radiation oropharyngeal mucositis is the most common and relatively difficult to deal with. Radiation ionizing radiation causes damage to the or...

AI Technical Summary

Problems solved by technology

[0003] For the treatment of radiation-induced oropharyngeal mucositis, Western medicine is mostly used at present: anti-inflammatory drugs, vitamins and mouthwash are used together, and the curative effect is often unsatisfactory, and the role of traditional Chinese medicine in this field has not been explored enough

One of the reasons is that most of the current methods of taking traditional Chinese medicines are made into decoctions for decoction. This method requires long-term decoction, which is time-consuming and laborious. The extraction is complete, resulting in the waste of traditional Chinese medicine