Radiomics-based brain glioma grading prediction method

Abstract

The present invention provides a method for grading and predicting brain gliomas based on radiomics, comprising the following steps: step 1, collecting original medical images of brain gliomas by conventional magnetic resonance imaging methods, and performing image processing on the collected original medical images Format and size unification and data de-privacy processing, to obtain a glioma medical image sample group; step 2, select one of the glioma medical image samples, and manually segment the sensory information in the glioma medical image sample region of interest; step 3, extracting the features of glioma in the region of interest; step 4, performing dimensionality reduction on the features of glioma extracted in step 3, selecting effective features, and generating a target feature set; step 5, in the brain Sampling with replacement is performed in the glioma medical image sample group, and steps 2 to 4 are repeated to generate a training set; step 6, the prediction model is trained using the Cox regression model according to the training set to generate a prediction model.

Description

technical field [0001] The present invention relates to radiomics auxiliary diagnosis technology, in particular, relates to a radiomics-based glioma grade prediction method. Background technique [0002] The technology based on medical imaging has been applied to the diagnosis and staging of cancer. Due to the characteristics of continuous angiogenesis, tissue invasion and metastasis of glioma, the boundary between normal tissue and glioma tissue is not clear, and the location of metastasis is uncertain. Determining the factors leading to the prediction of the prognosis of glioma has become a severe challenge in clinical research. At present, in the clinical aspect of glioma imaging, radiologists mainly make subjective and qualitative judgments on the grading diagnosis of gliomas in the examination results based on personal knowledge and experience, and the results of the judgments also contain simple opinions. Quantitative information cannot fully describe tumor informatio...

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Problems solved by technology

[0002] The technology based on medical imaging has been applied to the diagnosis and staging of cancer. Due to the characteristics of continuous angiogenesis, tissue invasion and metastasis of glioma, the boundary between normal tissue and glioma tissue is not clear, and the location of metastasis is uncertain. Determining the factors leading to the prognosis prediction of glioma becomes a severe challenge in clinical research

At present, in the clinical aspect of glioma imaging, radiologists mainly make subjective and qualitative judgments on the grading diagnosis of gliomas in the examination results based on personal knowledge and experience, and the results of the judgments also contain simple opinions. Quantitative information cannot fully describe tumor information, which is not conducive to doctors to formulate treatment plans and grade to predict the grade of glioma

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