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Traditional Chinese medicine composition for acute exacerbation of chronic obstructive pulmonary disease

A technology for chronic obstructive pulmonary disease and acute exacerbation, applied in drug combinations, respiratory diseases, pharmaceutical formulations, etc., can solve the problems of repeated disease, progressive aggravation, lack of treatment methods for the cause, etc., and achieve the effect of definite curative effect

Inactive Publication Date: 2018-01-12
SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of AECOPD is mainly based on western medicine, the main purpose is to relieve clinical symptoms such as cough and wheezing. However, due to the lack of treatment methods for the cause, patients often have relapses during the treatment process, and the trend is progressive.

Method used

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  • Traditional Chinese medicine composition for acute exacerbation of chronic obstructive pulmonary disease
  • Traditional Chinese medicine composition for acute exacerbation of chronic obstructive pulmonary disease
  • Traditional Chinese medicine composition for acute exacerbation of chronic obstructive pulmonary disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1 clinical experiment

[0020] 1. Materials and methods

[0021] (1) Inclusion and exclusion criteria

[0022] Inclusion criteria: (1) Patients who were diagnosed as COPD with phlegm-heat obstructing the lungs according to "Differential Diagnosis of TCM Syndrome" and "Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Diseases in Traditional Chinese Medicine (2011 Edition)"; 8th edition) in patients with AECOPD diagnostic criteria.

[0023] Exclusion criteria: (1) Patients with other diseases that may affect the treatment results; (2) Patients with special populations such as pregnant women, breastfeeding, and mental disorders; (3) Liver and kidney insufficiency, which may affect drug metabolism and excretion of patients.

[0024] (2) The research subjects selected 72 patients (including 48 males and 48 females) who were diagnosed with acute exacerbation of chronic obstructive pulmonary disease with phlegm-heat obstructing the lung...

Embodiment 2

[0048] Embodiment 2 outpatient treatment experiment

[0049] From 2017, 30 patients (18 males and 12 females) with acute exacerbation of chronic obstructive pulmonary disease (including 18 males and 12 females) with phlegm-heat blocking the lungs were selected in the outpatient clinic according to the standard of Example 1, and were treated with Xingxia Qutan Decoction. Xingxia Qutan Decoction The composition of phlegm soup is: Dannanxing 16-20g, Pinellia 16-20g, Trichosanthes 13-17g, Citrus aurantium 10-14g, Campanulaceae 10-14g, Scutellaria baicalensis 10-14g, Coptis 10-14g, Gardenia 10-14g, Yu Liren 10-14g, Morus alba 10-14g, Houttuynia cordata 10-14g, Atractylodes macrocephala 8-10g, Bergamot 8-10g, Curcuma 8-10g, Poria cocos 8-10g, Atractylodes 8-10g, thick Pu 5-7g, gypsum 5-7g, roasted licorice 2-4g. The component comparison is adjusted according to the condition of the disease. Take 1 dose per day after decoction. Continuous treatment for 28 days. Follow-up visits o...

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Abstract

At present, western medicines are mainly adopted to treat acute exacerbation of chronic obstructive pulmonary diseases, but because of the lack of etiological treatment means, a patient has disease reoccurrence frequently in the treatment process and has the trend of progressive aggravation. Through theoretical exploration and experiment research, the inventor discloses a traditional Chinese medicine composition used in acute exacerbation of chronic obstructive pulmonary diseases. The traditional Chinese medicine composition comprises traditional Chinese medicines such as arisaema cum bile, rhizoma pinellinae praeparata and complete dried trichosanthes kirilowii maxim. The traditional Chinese medicine composition disclosed by the invention aims to etiological treatment and is reasonable incomponent matching. Clinical tests show that a definite treatment effect can be achieved, and a remarkable effect can be achieved when being compared with that of a control group.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for acute exacerbation of chronic obstructive pulmonary disease. Background technique [0002] Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by incompletely reversible airflow limitation. COPD will become the third leading cause of death in the world after ischemic heart disease and cerebrovascular disease, posing a great threat to people's life and health. The clinical course of COPD is generally divided into stable phase and acute exacerbation phase (AECOPD). Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) refers to the process of sudden acute onset of patients on maintenance drug therapy due to infection and other reasons in the stable stage. Treatment options. [0003] Currently, Western medicine is the main treatment for AECOPD. The main p...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P11/00A61K33/06
Inventor 胡亚洁赵晓锦刘巍宋小莉
Owner SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE
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