Detection method for determining two preservatives in air filter screen

Abstract

The invention provides a detection method for determining two preservatives in an air filter screen. The detection method is used for determining content of MIT (2-methyl-4-isothiazolin-3-one) and OIT(2-octyl-2H-isothiazol-3-one). With the adoption of ultrasonic extraction, C18-SPE (solid phase extraction) cartridge based purification and HPLC (high performance liquid chromatography) detection, the two preservatives in the filter screen can be subjected to qualitative and quantitative analysis rapidly and efficiently. The method has the advantages of being high in yield, good in repeatabilityand high in sensitivity and can be used for detecting MIT and OIT in the air filter screen rapidly and efficiently.

Description

technical field [0001] The invention belongs to the field of analytical chemistry, in particular to the simultaneous determination of 2-methyl-4-isothiazolin-3-ketone (MIT) and 2-n-octyl-4-isothiazolin-3-ketone (OIT ) detection method, more specifically the method for qualitative and quantitative determination of MIT and OIT content in the air filter by ultrasonic extraction, solid phase extraction column purification and high performance liquid chromatography (HPLC). Background technique [0002] 2-Methyl-4-isothiazolin-3-one (MIT) and 2-n-octyl-4-isothiazolin-3-one (OIT) are both a heterocyclic structure, and their bactericidal principle mainly depends on the heterocyclic structure. The active part of the loop destroys the DNA molecules inside the bacterial cell, rendering the bacteria inactive. As commonly used fungicides, MIT and OIT have strong inhibitory and killing effects on a variety of fungi and bacteria, and are widely used in coatings, paints, inks, lubricants, ...

AI Technical Summary

Problems solved by technology

But little is known about their analytical detection methods on material matrices, especially in air filters

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