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Aqueous patch containing glucose amine compounds

A technology of glucosamine and compounds, which is applied in the field of a novel intake method of glucosamine compounds, which can solve the problems of limited absorption effect and achieve the effect of eliminating side effects caused by internal organs

Inactive Publication Date: 2018-01-19
廖钰贤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the dose applied to the skin each time is very small, the amount that can be absorbed is even less, and the effect of its absorption is also very limited.

Method used

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  • Aqueous patch containing glucose amine compounds
  • Aqueous patch containing glucose amine compounds
  • Aqueous patch containing glucose amine compounds

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The water-soluble pressure-sensitive adhesive was prepared by using the steps of Preparation Example 15 in the specification of Taiwan Invention Patent Application No. 102136412.

[0036] 6 parts by weight of 2-ethylhexyl acrylate (2-Ethylhexyl acrylate, 2-EHA), 13 parts by weight of (2-Hydroxyethyl acrylate, 2-HEA), 67 parts by weight of methacrylic acid omega-methylpenta Ethylene glycol ether ester (ω-Methyl pentaethyleneglycol methacrylate, PEMGA) acrylic monomer, and 9 parts by weight of PEG (MW = 900), 1.7 parts by weight of MAA, 3 parts by weight of 1,2-propylene glycol (propylene glycol), 0.3 parts by weight of natto extract mixture (NDE) (this extract mixture is to dilute the natto fermented product 3 times with water, filter out the particles of natto, and the gained aqueous solution is concentrated back to the original concentration and get), placed in a 1-liter reaction tank system with nitrogen reflux and temperature regulation, in which 120% by weight of de...

Embodiment 2

[0040] Mix 1.5 grams of menthol, 0.6 grams of camphor oil, 0.8 grams of eastern green oil, 0.7 grams of bergamot essential oil, 1.0 grams of castor oil polyethylene glycol emulsifier and 3.5 grams of water, and then vigorously stir to obtain a plant aromatic essential oil emulsion.

[0041] Add this plant aromatic essential oil emulsion to the coating composition used to form the aqueous coating composition containing the active ingredient layer in Example 1, and roll and stir for 10 minutes to obtain a water-soluble pressure sensitive oil containing glucosamine hydrochloride and emulsified essential oil. Adhesive composition. Repeat the coating steps of Example 1 and the steps of covering with non-woven cloth to obtain the water-based patch of the present invention.

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Abstract

The invention provides an aqueous patch containing glucose amine compounds., comprising base cloth, an aqueous adhesive layer containing effective ingredients on the surface of the base cloth or a separation type paper or a separation type file which can be adhered to the aqueous adhesive layer containing the effective ingredients, wherein the aqueous adhesive layer containing the effective ingredient comprises the glucose amine compounds includes the glucose amine compounds and a water-soluble pressure-sensing adhesive. The aqueous path containing the glucose amine compound has advantages ofa liniment and the absorption of the aqueous patch does not go through internal guts for digestion and delivery, so that the considerations that the absorption process could be compromised by gastricacid and side effects could impact on the internal guts can be eliminated. Furthermore, the aqueous adhesive layer containing the effective ingredients has a certain thickness, the glucose amine compounds are water-soluble , the quantity of the glucose amine compounds which can freely move in the aqueous adhesive layer is big and the aqueous patch can stay long on the skin, so that the absorptiondoes by the human body is enough.

Description

technical field [0001] The present invention relates to a novel intake mode of glucosamine compounds, in particular to a percutaneous absorption intake mode using a water-based patch as a carrier. Background technique [0002] At present, most of the intake methods of glucosamine compounds are oral intake made into lozenges or drinks, and a small part are made into ointment-like liniments for external use. In oral intake, more than 80%-90% of glucosamine compounds may be broken down by strong acids in the digestive system. Coupled with the fact that the hand or foot joints are far away from the digestive system, the remaining glucosamine compounds can be delivered to the joints that really need to be used. That is to say, it takes a long time to feel the effects of oral intake by swallowing or drinking. In addition, there may be concerns about side effects for patients with internal organ diseases such as kidneys or cardiovascular diseases. [0003] If you use external li...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K31/7008A61K31/726A61P19/02
Inventor 廖钰贤廖子瑛廖子瑄
Owner 廖钰贤
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