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A system and method for detecting the state of cerebral cortex in disorders of consciousness

A cerebral cortex and state detection technology, applied in the field of biomedical engineering, can solve problems such as narrow application range, high cost, and complicated operation, and achieve the effect of getting rid of the dependence on clinical conditions, low clinical requirements, and reduced computing costs

Active Publication Date: 2021-04-13
BEIJING NORMAL UNIVERSITY
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  • Claims
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AI Technical Summary

Problems solved by technology

However, patients with impaired consciousness generally have severe brain damage, and it is difficult to preserve the corresponding neural pathways. Therefore, the scope of application of this method in clinical practice is narrow.
Although functional magnetic resonance technology can give individualized judgments, it can only identify patients with particularly good cortical conditions based on the results, but cannot provide numerical indicators for doctors to refer to. Moreover, this method is complicated to operate and expensive, and cannot Popularized in clinical application
At present, foreign countries have reported that a method similar to the present invention is used to detect the cortical state of disturbance of consciousness, that is, the disturbance complexity index, but the algorithm is extremely complex and time-consuming, and it is difficult to promote it in clinical applications.

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  • A system and method for detecting the state of cerebral cortex in disorders of consciousness
  • A system and method for detecting the state of cerebral cortex in disorders of consciousness
  • A system and method for detecting the state of cerebral cortex in disorders of consciousness

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Embodiment Construction

[0020] The embodiments of the present invention are described in detail below, and the embodiments are only used to explain the present invention, and should not be construed as limiting the present invention.

[0021] Specific examples of the present invention are described below.

[0022] This technical solution uses transcranial magnetic stimulation to directly induce EEG responses in the cortex, and the cerebral cortex state detection algorithm is based on the evoked EEG calculations. The entire implementation process does not require the active participation of patients, and completely gets rid of the clinical conditions of the patient's peripheral nerve pathways. Dependence, so that it can provide cerebral cortex state detection for more patients, and has wider applicability. Since the design of this technical solution uses evoked EEG, it can provide individualized detection results compared with the resting state EEG algorithm, which is easy for clinical interpretation....

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Abstract

The invention discloses a cerebral cortex state detection system for disturbance of consciousness, which comprises a brain response signal synchronous acquisition module, a response signal noise processing module and a cerebral cortex state detection algorithm module. The response signal synchronous acquisition module includes transcranial magnetic stimulation and magnetically compatible EEG equipment; the EEG cap adopts a 64-channel high-density EEG cap; the transcranial magnetic stimulation coil adopts an 8-shaped coil. The magnetic field was placed in the left dorsolateral prefrontal cortex (the F3 electrode position in the 10‑20 EEG system) perpendicular to the direction of the scalp. The invention fills up the blank of the state detection system and method of the cerebral cortex of the disturbance of consciousness. Compared with the current clinical research method, the present invention has the advantages of economy, convenience, simple calculation, strong applicability, suitable for clinical promotion and the like.

Description

technical field [0001] The invention belongs to the field of biomedical engineering, and specifically relates to a method based on engineering and informatics, which is used for detecting the state characteristics of the cerebral cortex of patients with impaired consciousness. Background technique [0002] At present, there is basically no mature and reliable method for detecting the cortical state of disturbance of consciousness clinically. Individual cutting-edge medical research institutions have carried out the detection of cortical reactivity in disturbance of consciousness based on resting-state EEG, event-related potential and functional magnetic resonance technology. However, there are serious defects in the above methods, which restrict the application of these methods in clinical practice. The details are as follows: the existing detection methods based on resting-state EEG must be based on the statistical results of large samples, and cannot provide individualize...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/377A61B5/383A61B5/00
Inventor 李小俚王凯
Owner BEIJING NORMAL UNIVERSITY
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