Induction culture medium and induction method for differentiating umbilical stalk mesenchymal stem cells into neuron-like cells

A technology for inducing culture medium and stromal cells, which is applied in the field of induction medium for umbilical cord mesenchymal stem cells to differentiate into neural-like cells, which can solve the problems of limited sources and achieve the effect of short induction time.
CN107630003AActive Publication Date: 2018-01-26广州市天河诺亚生物工程有限公司 +1
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
广州市天河诺亚生物工程有限公司
Publication Date
2018-01-26

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Abstract

The invention belongs to the field of biotechnology, and specifically relates to an induction culture medium and an induction method for differentiating umbilical stalk mesenchymal stem cells into neuron-like cells. The invention provides the induction culture medium and induction method for differentiating umbilical stalk mesenchymal stem cells into neuron-like cells. The induction culture mediumcomprises piceatannol and a base culture medium, and the concentration of piceatannol in the induction culture medium is 62.5-250mu mol / L. According to the induction method, the umbilical stalk mesenchymal stem cells are cultivated in the induction culture medium and are differentiated directionally so as to obtain neuron-like cells. The induction method costs a short induction time, and can generate neuron-like cells with neurons and neuroglia through induction, thereby providing a new cell source for damage repairing of a central nervous system.
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Description

technical field

[0001] The invention belongs to the field of biotechnology, and in particular relates to an induction medium and an induction method for differentiating umbilical cord mesenchymal stem cells into nerve-like cells. Background technique

[0002] Nervous system diseases seriously threaten human health, such as the well-known Parkinson's disease and Alzheimer's disease, as well as hemorrhagic stroke, traumatic diseases and spinal cord injuries, all of which are due to the failure of differentiated and mature nerve cells to divide and proliferate to compensate caused by damaged and dead cells. At present, autologous nerve transplantation is mostly used to treat nervous system diseases, but the source of autologous nerve transplantation is limited, so finding cells from other sources is the key to cell transplantation and treatment of nervous system diseases.

[0003] Mesenchymal stem cells (mesenchymal stem cells, MSCs) are pluripotent stem cells with high self-r...

Claims

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