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Combination Of At Least One Protease Inhibitor And At Least One Active Principle For Use In The Prevention And/Or Treatment Of Skin Lesions

A technology of protease inhibitors and active ingredients, applied to peptide/protein ingredients, organic active ingredients, inorganic active ingredients, etc.

Active Publication Date: 2018-02-09
EURODRUG LAB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0025] However, when all the above-mentioned ingredients are used alone, only the clinical manifestations of diaper rash can be relieved

Method used

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  • Combination Of At Least One Protease Inhibitor And At Least One Active Principle For Use In The Prevention And/Or Treatment Of Skin Lesions
  • Combination Of At Least One Protease Inhibitor And At Least One Active Principle For Use In The Prevention And/Or Treatment Of Skin Lesions
  • Combination Of At Least One Protease Inhibitor And At Least One Active Principle For Use In The Prevention And/Or Treatment Of Skin Lesions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076]

Embodiment 2

[0078]

[0079]

Embodiment 3

[0081]

[0082]

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PUM

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Abstract

The invention relates to a combination comprising at least one protease inhibitor, which can be of different origins, such as plants, fruits, rice bran, cowpea seeds, soybean or potato and at least one additional active principle, selected from zinc oxide, dexpanthenol, panthenol, benzalkonium chloride, cetrimide, clotrimazole, nystatin, dimethicone, aloe vera, or calendula and to its use in the prevention and / or treatment of skin damages caused by urine and / or faeces and as adjuvant in skin repair. The invention further relates to said combination in association with a further active principles and to its use in prevention and / or treatment of skin damages caused by proteases in the faeces and as adjuvant in skin repair.

Description

Background technique [0001] Diaper rash is a common form of inflamed skin (dermatitis) that appears as a patchwork of bright red skin on the buttocks of infants and also in adults with urinary and / or fecal incontinence, incontinence Perianal dermatitis in elderly patients, long-term hospitalized patients, and bedridden patients with ulcers. [0002] Diaper rash is usually associated with persistently wet or infrequently changed diapers, diarrhea and the use of plastic pants to cover diapers. After introducing solid foods to an infant's diet, when a breastfeeding mother eats for a given week, when an infant changes from breast milk to formula, when changing from one type of formula to another, at birth Diaper rash can also occur during teething, or when the infant is taking antibiotics (1). [0003] Diaper rash is characterized by [0004] • Skin signs: The hallmark of diaper rash is red, swollen and fragile-looking skin in the diaper area (buttocks, thighs and genitals), wh...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K31/695A61K36/28A61K36/81A61K31/164A61K38/56A61K31/7048A61K33/30A61K36/48A61K36/896A61K36/886A61K31/14A61K31/4174A61P17/00
CPCA61K31/14A61K31/164A61K31/4174A61K31/695A61K31/7048A61K33/30A61K36/28A61K36/48A61K36/81A61K36/886A61K36/896A61K38/56A61K45/06A61K2300/00A61K9/0014A61K9/06A61P17/00
Inventor A·阿桑德里
Owner EURODRUG LAB
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