Malus toringoides leaf extract tablet and preparation method thereof

An extract, russian technology, applied in the directions of pill delivery, pharmaceutical formulations, drug combinations, etc., can solve the problems of uncontrollable quality, single application form, restricting the development and application of russian, avoid sudden drop in blood sugar, and improve safety. Effect

Active Publication Date: 2018-02-23
炉霍雪域俄色有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, the application of esse is mostly in health care products, such as tea, but there are very few studies on its application in pharmaceutical preparations, and the application form is single and the quality is uncontrollable, which seriously limits the development and application of esse

Method used

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  • Malus toringoides leaf extract tablet and preparation method thereof
  • Malus toringoides leaf extract tablet and preparation method thereof

Examples

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Effect test

Embodiment 1

[0037] This example provides a kind of Russian color extract and its preparation method. This method uses Russian color fruit and Russian color fruit as raw materials at the same time, and adopts the method of microbial fermentation to extract the active ingredients in it. Macromolecular substances such as starch and polysaccharides are decomposed into small molecules that are easy to be absorbed, and new active ingredients are produced, that is, the extraction efficiency of the Russian color extract obtained by this extraction method is high and the properties are excellent. Specifically, the preparation method of the Russian extract provided in this embodiment includes the following steps:

[0038] Step 1: According to the mass ratio of 1:0.5, take fresh Russian leaves and Russian fruits, wash them separately, then add drinking water according to the ratio of material to liquid at 1:1, heat and boil for 30 minutes, remove and drain, and cool to room temperature, then mix the...

Embodiment 2

[0042]This example provides a kind of Russian color extract and its preparation method. This method uses Russian color fruit and Russian color fruit as raw materials at the same time, and adopts the method of microbial fermentation to extract the active ingredients in it. Macromolecular substances such as starch and polysaccharides are decomposed into small molecules that are easy to be absorbed, and new active ingredients are produced, that is, the extraction efficiency of the Russian color extract obtained by this extraction method is high and the properties are excellent. Specifically, the preparation method of the Russian extract provided in this embodiment includes the following steps:

[0043] Step 1: According to the mass ratio of 1:0.8, take fresh Russian leaves and Russian fruits, wash them separately, then add drinking water according to the ratio of material to liquid at 1:1, heat and boil for 30 minutes, remove and drain, and cool to room temperature, then mix the ...

Embodiment 3

[0047] This example provides a Russian-colored extract tablet and a preparation method thereof. The method prepares the Russian color extract into shaped tablets, so that it has quality controllability and improves the safety of its clinical application; the process is reasonable, simple and easy, and the prepared tablet has a slow-release function, which solves the problem of drug The problem of sudden release is scientific and reasonable. . Specifically, the preparation method of the Russian extract tablet provided in this embodiment includes the following steps:

[0048] Step 1: Weigh the Russian color extract, slow-release agent, microcrystalline cellulose and hypromellose according to the mass ratio of 4:2:1:1, then crush them respectively, and pass through a 100-mesh sieve for later use. Among them, the sustained-release agent has stearic acid and sodium hydroxymethyl cellulose in a mass ratio of 1:2.

[0049] Step 2: Put the sieved Russian color extract, sodium hydro...

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Abstract

The invention discloses a malus toringoides leaf extract tablet and a preparation method thereof, and relates to the field of pharmaceutical preparations. According to the present invention, the malustoringoides leaf extract tablet is prepared by using a malus toringoides leaf extract, a slow release agent, a filler and an adhesive as raw materials, wherein the malus toringoides leaf extract is prepared through microbial fermentation; the malus toringoides leaf extract has slow release property and blood glucose lowering effect; after the malus toringoides leaf extract is prepared into the molded tablet, the application range of the malus toringoides leaf is expanded, and the quality of the malus toringoides leaf can be controlled so as to improve the application safety; the slow releaseagent contains the corrosive and hydrophilic gelling slow-release framework materials, such that the suitable drug release rate can be achieved through the combination of the two materials; and the malus toringoides leaf extract tablet preparation method has advantages of reasonable process, simpleness and easy performing.

Description

technical field [0001] The invention relates to the field of pharmaceutical preparations, in particular to a Russian extract tablet and a preparation method thereof. Background technique [0002] The "three highs" refer to high blood pressure, high blood sugar (diabetes) and hyperlipidemia. They are the "diseases of wealth" derived from modern society. They may exist alone or may be related to each other. With the improvement of living standards and changes in the rhythm of life, the "three highs" have become like "the old swallows before Wang Xietang, flying into the homes of ordinary people", especially the common diseases of the middle-aged and elderly people over 50 years old, and they have recently become obvious. rejuvenation trend. The number of people who die from cardiovascular and cerebrovascular diseases is as high as 15 million every year in the world, ranking first among various causes of death. Cardiovascular and cerebrovascular diseases have become the "numb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K9/22A61K9/28A61K47/38A61K47/12A61P3/10A61P3/06A61P9/12A61K127/00A61K131/00
CPCA61K9/0002A61K9/2013A61K9/2054A61K9/2806A61K36/73A61K2236/19A61K2236/331
Inventor 谢雨蕉雷敏毛羽李敏
Owner 炉霍雪域俄色有限责任公司
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