Paste as well as preparation method and application thereof

A paste, zinc oxide technology, applied in the direction of dental preparations, pharmaceutical formulations, pharmaceutical science, etc., to achieve good biocompatibility, good stability, easy absorption effect

Inactive Publication Date: 2018-03-06
PEKING UNIV SCHOOL OF STOMATOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is still no ideal root ca

Method used

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  • Paste as well as preparation method and application thereof
  • Paste as well as preparation method and application thereof
  • Paste as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 prepares paste 1#

[0039] The weight percent of zinc oxide and clove oil chelate in the paste is 60wt%; the weight percent of iodoform is 38wt%; the rest is calcium hydroxide, and the weight percent sum of each component is 100wt%.

[0040] The specific preparation method is as follows: zinc oxide powder and clove oil (weight ratio is 3:1) are mixed on a sterilized glass plate until uniform, and the blending is repeated to be shiny, the adjusting knife can be pulled up and in a semi-fluid state, and then Add iodoform and calcium hydroxide in the above percentage by weight, and mix to form a paste, which can be used for root canal filling. The paste is labeled 1#.

Embodiment 2

[0041] Embodiment 2 prepares paste 2#

[0042] The weight percent of zinc oxide and clove oil chelate in the paste is 65wt%; the weight percent of iodoform is 33wt%; the rest is calcium hydroxide, and the weight percent sum of each component is 100wt%.

[0043] The specific preparation method is as follows: zinc oxide powder and clove oil (weight ratio is 3:1) are mixed on a sterilized glass plate until uniform, and the blending is repeated to be shiny, the adjusting knife can be pulled up and in a semi-fluid state, and then Add iodoform and calcium hydroxide in the above percentage by weight, and mix to form a paste, which can be used for root canal filling. The paste is labeled 2#.

Embodiment 3

[0044] Embodiment 3 prepares paste 3#

[0045] The weight percent of zinc oxide and clove oil chelate in the paste is 70wt%; the weight percent of iodoform is 28wt%; the rest is calcium hydroxide, and the weight percent sum of each component is 100wt%.

[0046] The specific preparation method is as follows: zinc oxide powder and clove oil (weight ratio is 3:1) are mixed on a sterilized glass plate until uniform, and the blending is repeated to be shiny, the adjusting knife can be pulled up and in a semi-fluid state, and then Add iodoform and calcium hydroxide to form a paste, which can be used for root canal filling. The paste is labeled 3#.

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PUM

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Abstract

The invention discloses paste which comprises the following components: zinc oxide and clove oil chelate, iodoform and calcium hydroxide. The paste provided by the invention is used for primary teethroot canal filling materials, has excellent stability and is easy to absorb, and the matched-degree of the degradation velocity and the physiological absorption speed of the tooth root is superior tothat of the conventional clinically used material Vitapex (containing iodoform and calcium hydroxide) and ZOE (Zinc Oxide-Eugenol); and the clinical and radiological success rate is not lower than that of the conventional material.

Description

technical field [0001] The application relates to a paste and its preparation method and application, belonging to the field of chemical materials. Background technique [0002] The current study found that the degradation rate of primary tooth root filling materials has an impact on the replacement of primary and permanent teeth. Root filling materials with a slow degradation rate may form large, hard clumps outside the apical foramen of deciduous teeth and affect the eruption of the underlying permanent teeth; if the degradation rate is too fast, the root canal reinfection of deciduous teeth cannot be effectively controlled. [0003] The ideal deciduous tooth root canal filling material should have the following characteristics: absorption rate similar to deciduous tooth root, harmless to the apical tissue, harmless to the developing inherited permanent tooth germ, easy to be absorbed beyond the apical foramen, good antibacterial Strong, easy to be filled into the root ca...

Claims

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Application Information

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IPC IPC(8): A61K6/04A61K6/02A61K6/00
CPCA61K6/54A61K6/80A61K6/84
Inventor 陈小贤刘星纲
Owner PEKING UNIV SCHOOL OF STOMATOLOGY
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