Micro-fluidic chip bonding method and micro-fluidic chip

A microfluidic chip and bonding technology, which is applied in the field of bioscience micro-analysis system, can solve the problems of not being able to package the microfluidic chip firmly, and achieve the effect of reasonable structure, obvious bonding effect and guaranteed stability

Active Publication Date: 2018-03-09
成都微康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0009] The technical problem to be solved by the present invention is that the bonding method of the microfluidic chip in the prior art cannot not only firmly package the microfluidic chip, but also not have a physical or chemical impact on the final microstructure of the plastic microfluidic chip , p...

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  • Micro-fluidic chip bonding method and micro-fluidic chip

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Embodiment

[0032] A microfluidic chip bonding method for bonding a substrate 4 with a microchannel structure 1 on the surface and a cover sheet together to form a microfluidic chip with a preset cavity structure, including:

[0033] Step 1, providing a microfluidic chip substrate 4, the upper surface of the substrate 4 is provided with a microchannel structure 1;

[0034] Step 2, setting ultrasonic bonding energy directors 2 at the periphery of the microchannel structure 1 on the upper surface of the substrate 4, the width and thickness of the ultrasonic bonding energy directors 2 are both 100-500 μm, more optimally, 200 μm is selected; the ultrasonic bonding energy director 2 cannot directly contact the edge of the microchannel structure 1, and is 100 μm-2 mm away from the edge of the microchannel structure 1, and more optimally, 200 μm is selected;

[0035] Step 3, paste double-sided adhesive tape 3 on the upper surface of the substrate 4, and bond the cover sheet to the substrate 4. T...

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Abstract

The invention relates to the technical field of bioscience micro-total analysis systems, in particular to a micro-fluidic chip bonding method and a micro-fluidic chip. The method includes: providing amicro-fluidic chip substrate, wherein the upper surface of the substrate is provided with a microchannel structure; arranging ultrasonic bonding energy conducting ribs at the edge around the microchannel structure of the upper surface of the substrate or around a position, corresponding to the microchannel structure of the substrate, of a cover plate; adhering a surface pasting double-side adhesive tape on the substrate or the cover plate to glue the cover plate with the substrate; performing ultrasonic bonding on the substrate and the cover plate to enable first-step bonding; applying pressure to fix the chip or hot-pressing the same to enable the substrate and the cover plate which are pasted by the double-side adhesive tape to be firmly bonded. By the method, bonding stability of the micro-fluid chip can be ensured, and own physiochemical properties of the micro-fluidic chip can be avoided being affected, so that detection results are not interfered.

Description

technical field [0001] The invention relates to the technical field of bioscience micro-total analysis systems, in particular to a microfluidic chip bonding method and a microfluidic chip. Background technique [0002] The bonding link of the microfluidic chip is one of the key links in the preparation of the microfluidic chip, and the quality of the bonding directly affects the practical application of the microfluidic chip. At present, the main issues that need to be paid attention to in the bonding process of microfluidic chips include: [0003] 1. It is required that the chip can be connected, and the microchannel has airtightness, and has sufficient mechanical strength after bonding to avoid cracking and liquid leakage. [0004] 2. Avoid deformation, blockage or other influences on the microchannel during the bonding process. [0005] 3. When using organic matter for bonding, it is necessary to avoid changes in the physical and chemical properties of the surface. [...

Claims

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Application Information

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IPC IPC(8): B29C65/08B29C65/48B01L3/00
CPCB01L3/5027B01L2200/10B01L2300/0861B01L2300/0887B01L2300/12B29C65/08B29C65/48
Inventor 唐勇
Owner 成都微康生物科技有限公司
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