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Method for preparing lyophilized powder of composition with acne removal efficacy

A technology of composition and freeze-dried powder, which is applied in the field of preparation of freeze-dried powder, can solve the problems of weak anti-oxidation ability, unable to effectively prevent acne scars and acne scars, skin damage, and low extraction efficiency

Active Publication Date: 2018-03-23
广州领衔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the deficiencies of the prior art, the object of the present invention is to provide a composition with anti-acne effect and a preparation method of its freeze-dried powder, which can effectively solve the problem of extracting the active substances of plant fruits that are currently produced. Low efficiency, containing preservatives, hormones that damage the skin, make the skin resistant to drugs, and weak antioxidant capacity cannot effectively prevent the formation of acne scars and acne scars

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The composition with anti-acne effect includes the following components according to the weight fraction:

[0041] 10 parts of traditional Chinese medicine extracts, 3 parts of Aphrodisiac Sinensis extract, 3 parts of Luo Han Guo extract, 4 parts of Indigo fruit extract, 2 parts of Guangxi sweet tea fruit extract, 6 parts of mango extract, 6 parts of longan extract, apple 10 parts of extract, 0.5 parts of nano graphene, 0.01 part of fibroblast growth factor, 1 part of dextran, 0.05 part of polyglutamic acid, 2 parts of mannitol, 65 parts of deionized water; Its ingredients are: 5 parts of licorice extract, 5 parts of Danshen extract.

Embodiment 2

[0043] The composition with anti-acne effect includes the following components according to the weight fraction:

[0044] 13 parts of traditional Chinese medicine extracts, 4 parts of Aphrodisiac Sinensis extract, 4 parts of Luo Han Guo extract, 5 parts of Indigo fruit extract, 3 parts of Guangxi sweet tea fruit extract, 7 parts of mango extract, 7 parts of longan extract, apple 11 parts of extract, 0.5 parts of nano graphene, 0.01 part of fibroblast growth factor, 2 parts of dextran, 0.08 parts of polyglutamic acid, 3 parts of mannitol, 70 parts of deionized water; Its ingredients are: 5 parts of licorice extract, 5 parts of Danshen extract.

Embodiment 3

[0046] The composition with anti-acne effect includes the following components according to the weight fraction:

[0047] 15 parts of traditional Chinese medicine extracts, 5 parts of Aphrodisiac Sinensis extract, 5 parts of Luo Han Guo extract, 6 parts of Indigo fruit extract, 4 parts of Guangxi sweet tea fruit extract, 8 parts of mango extract, 8 parts of longan extract, apple 12 parts of extract, 0.5 parts of nano-graphene, 0.01 part of fibroblast growth factor, 2 parts of dextran, 0.1 part of polyglutamic acid, 4 parts of mannitol, 85 parts of deionized water; Its ingredients are: 5 parts of licorice extract, 5 parts of Danshen extract.

[0048] The raw material extraction method in each embodiment is as follows:

[0049]The preparation method of longan extract adopts pectinase and cellulase dual-enzyme simultaneous enzymatic hydrolysis extraction method, the specific preparation method is as follows: fresh longan is dried with hot air at 80°C, peeled and cored to obtain ...

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Abstract

The invention relates to a method for preparing lyophilized powder of a composition with an acne removal efficacy. The method includes: proportionally adding polyglutamic acid and deionized water intoa homogenizer, homogenizing for 10min at 78 DEG C, completely dissolving to obtain A, and naturally cooling A; when A is cooled to about 50 DEG C, proportionally adding mannitol and dextran, and wellmixing to obtain B; when B is cooled to about 30 DEG C, proportionally adding traditional Chinese medicine extract, ficus pumila extract, fructus momordicae extract, lonicera caerulea extract, rubussuavissimus extract, mango extract, longan extract, apple extract, nano graphene and fibroblast growth factors, well stirring to obtain C, freezing C for 20h at -25 DEG C, and discharging after qualification; filling the frozen C, adding into vacuum freeze drying equipment, and performing vacuum freeze drying for 35h under conditions of 7Pa in vacuum degree and -50 DEG C in temperature, so that the lyophilized powder of the composition with the acne removal efficacy is obtained.

Description

technical field [0001] The invention belongs to the technical field of preparation of daily skin care products, and in particular relates to a method for preparing freeze-dried powder of a composition with acne-removing effects. Background technique [0002] Acne has another name called acne, and the occurrence of acne is mainly closely related to factors such as excessive sebum secretion, pilosebaceous duct blockage, bacterial infection and inflammatory response. After entering puberty, the level of androgens in the human body, especially delphitonin, increases rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum. At the same time, abnormal keratinization of the pilosebaceous duct causes duct blockage, sebum discharge obstruction, and the formation of keratin plugs, that is, micropowder thorns. A variety of microorganisms in hair follicles, especially Propionibacterium acnes, multiply in large numbers. The lipase produced by Prop...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/19A61K8/64A61K8/02A61Q19/00A61Q19/08A61Q17/00A61P17/10A61P31/02A61P31/04A61P29/00
CPCA61K8/022A61K8/19A61K8/64A61K8/97A61K2800/413A61K2800/524A61K2800/592A61K2800/5922A61K2800/782A61K2800/805A61K2800/82A61K2800/84A61Q17/005A61Q19/00A61Q19/08
Inventor 李人普
Owner 广州领衔生物科技有限公司
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