Traditional Chinese medicine composition for preventing and treating colorectal adenoma as well as preparation method and application of traditional Chinese medicine composition

A technology of colorectal and composition, applied in the field of traditional Chinese medicine composition for the prevention and treatment of colorectal adenoma, which can solve the problems of ineffective cure and increased suffering of patients

Inactive Publication Date: 2018-04-06
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Searching the literature in recent years, there is no drug for the prevention and treatment of colorectal adenoma. Western medicine mostly uses colonoscopy for surgical removal, which can not be cured effectively and increases the suffering of patients

Method used

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  • Traditional Chinese medicine composition for preventing and treating colorectal adenoma as well as preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The traditional Chinese medicine composition for preventing and treating colorectal adenoma is made of the following traditional Chinese medicine raw materials in the following weight ratio: black plum: silkworm = 1:1.

[0015] Preparation and dosage: firstly pulverize the traditional Chinese medicine raw materials in the weight ratio with a pulverizer, and take the whole powder to make big honeyed pills, and the daily dosage is 36g according to the whole powder.

Embodiment 2

[0017] The traditional Chinese medicine compound composition for preventing and treating colorectal adenomatous polyps and hyperplastic polyps is made of the following traditional Chinese medicine raw materials in the following weight ratio: black plum: silkworm = 1:0.5.

[0018] Preparation and dosage: firstly mix the raw materials in the weight ratio, add 10 times the mass of pure water, decoct for 40 minutes, take the juice and take it warmly twice, and the daily dose is 50g based on the composition.

Embodiment 3

[0020] The traditional Chinese medicine recurrence prevention and treatment composition for colorectal adenomatous polyps and hyperplastic polyps is made of the following traditional Chinese medicine raw materials in the following weight ratio: black plum: silkworm = 1:2.

[0021] Preparation and dosage: first mix the raw materials in the weight ratio, add 8 times the mass of 30% ethanol solution, heat and reflux for extraction for 60 minutes, concentrate the extract under reduced pressure until it has no alcohol smell, and dissolve it in 200ml of hot water , taken warmly twice, and the daily dose is 54g in terms of composition.

[0022] The beneficial effects of the Chinese medicine compound preparation of the present invention are set forth below through test examples, including animal pharmacodynamic tests and clinical efficacy tests.

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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly relates to a traditional Chinese medicine composition for preventing and treating colorectal adenoma as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the raw material drugs including smoked plums and bombyxbatryticatus in a weight ratio of 1 to (0.2-3). The preparation method comprises the steps of directly crushing smoked plums and bombyx batryticatus, and directly utilizing crushed smoked plums and bombyx batryticatus as drugs; or extracting smoked plums and bombyx batryticatus by virtue of a solvent, and utilizing extracts as drugs. The invention simultaneously provides application of the traditional Chinese medicine composition in the preparation of drugs for preventing and treating colorectal adenoma and preventing the relapse of colorectal adenoma.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for preventing and treating colorectal adenoma, its preparation method and application. Background technique [0002] Colorectal adenoma is now recognized as the most common precancerous lesion of colorectal cancer, and more than 80% of colorectal cancers evolve from adenoma. Colorectal adenoma has an insidious onset and almost no obvious clinical symptoms. A few manifest as changes in bowel habits, blood and mucus in the stool, loose stools, increased frequency, and abdominal discomfort to varying degrees. symptom. The principle of treatment for colorectal adenomas is to remove them as soon as they are discovered. Complete resection of adenomas can reduce the incidence of cancer, but the annual recurrence rate is as high as 10% to 15%, which makes the patients suffer physically and mentally. Therefore, it is of great signif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P35/00A61K35/64
CPCA61K35/63A61K36/736A61K2300/00
Inventor 付晓伶李琦王亚丛冯媛媛潘亚敏
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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