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A neuron electronic pulse generation system and method

An electronic pulse and generation system technology, which is applied in electrotherapy, therapy, physical therapy, etc., can solve the problems of current pulse stimulation and the inability to provide set waveforms for neurons, and achieve the effect of meeting stimulation needs

Inactive Publication Date: 2021-04-13
AFFILIATED HOSPITAL CHINA ACADEMY OF MILITARY MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a neuron electronic pulse generation system and method to solve the problem that the existing electronic equipment cannot provide neurons with current pulse stimulation with a set waveform and set noise

Method used

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  • A neuron electronic pulse generation system and method
  • A neuron electronic pulse generation system and method
  • A neuron electronic pulse generation system and method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] In order to achieve the above object, the specific block diagram of the system of the present invention is as follows figure 1 Shown: a neuron electronic pulse generation system, the neuron electronic pulse generation system includes:

[0043] The central processing module presets waveform parameters and noise parameters, and generates noise digital signals according to the noise parameters. In the embodiment of the present invention, the central processing module adopts the embedded microcontroller of ARM Cortex-M3 architecture, the main frequency is 100MHz; the memory size is 2M; the NANDFLASH memory size is 128M; it is equipped with a real-time operating system to ensure the real-time performance and stability of the system, and is responsible for the entire system Input and output control, waveform processing. The central processing module is respectively connected to the waveform generation module and the noise digital-to-analog conversion module, and is used to s...

Embodiment 2

[0052] On the basis of Embodiment 1, the embodiment of the present invention can specifically adopt such as figure 2 The connection form shown, that is

[0053] In the embodiment of the present invention, the waveform generation module is a programmable waveform generator AD9833 as a waveform output source, and the schematic diagram of AD9833 is as follows image 3 As shown, according to the input parameters, set the waveform type output of the waveform generator to be a sine wave, a square wave or other waveforms. The analog stimulation signal is sent to the first amplifier after being filtered; the first amplifier is used for adjusting the amplitude of the analog stimulation signal. In the embodiment of the present invention, the first amplifier can adopt the programmable gain amplifier AD8320, and the schematic diagram of AD8320 is as follows Figure 4 shown.

[0054] In the embodiment of the present invention, the noise digital-to-analog conversion module takes the hig...

Embodiment 3

[0061] The present invention also provides a neuron electronic pulse generation method, comprising the following steps:

[0062] Set waveform parameters and noise parameters;

[0063] Generate pulse signals according to waveform parameters;

[0064] generate a noise signal according to noise parameters;

[0065] The pulse signal and the noise signal are superimposed and mixed to obtain an analog stimulation signal;

[0066] The analog stimulation signal is output through the stimulation electrode;

[0067] Analyze and monitor simulated stimulus signals.

[0068] The inventive method has the following advantages:

[0069] The invention can output current simulation stimulation signals that meet the requirements according to the set waveform parameters, and supports noise superposition at the same time, so as to meet the user's stimulation requirements for rat brain nerves.

[0070] The present invention can observe the current current output waveform in real time through t...

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Abstract

The invention discloses a neuron electronic pulse generation system and method, which are used to solve the problem that the existing electronic equipment cannot provide the neuron with a current pulse stimulation with a set waveform and a set noise. It includes: a central processing module, which presets waveform parameters and noise parameters, and generates noise digital signals according to the noise parameters. The waveform generating module generates an analog stimulus signal according to the waveform parameters. The noise digital-to-analog conversion module converts the noise digital signal into a noise analog signal. The integrated processing module is used for superimposing and mixing the analog stimulation signal and the noise analog signal, so that the mixed current analog signal is output through the stimulating electrodes. The output feedback analog-to-digital conversion module performs analog-to-digital conversion on the mixed current analog signal and feeds it back to the central processing module. The central processing module analyzes and monitors the feedback signal in real time and adjusts the output of the stimulation signal. The display module displays the output waveform, waveform parameters and noise parameters in real time.

Description

technical field [0001] The invention relates to the technical field of electronic pulse generation, in particular to a neuron electronic pulse generation system and method. Background technique [0002] In the process of studying the stochastic resonance characteristics and mechanism of dopamine neurons in the substantia nigra compacta of Parkinson's rats, it is necessary to stimulate the rat neurons with current pulses in order to give the rat brain deep nuclei substantia nigra compact nuclei The nucleus is stimulated with a low voltage of 3.5HZ to 10Hz, and the nerve nucleus is electrically stimulated through the nerve electrical stimulation needle. The research found that the noise carried in the signal may be an important reason for the onset of Parkinson's disease. Therefore, it should be necessary to properly add noise when applying current pulse stimulation to rat neurons. [0003] In order to achieve the above purpose, there is an urgent need for an electronic devi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N1/36
CPCA61N1/3605A61N1/36125
Inventor 薛伟宁
Owner AFFILIATED HOSPITAL CHINA ACADEMY OF MILITARY MEDICAL SCI